Wellbutrin Side Effects

Wellbutrin (Bupropion) is an antidepressant of the aminoketone class marketed by GlaxoSmithKline. Zyban, also marketed by GlaxoSmithKline, has the same chemical properties but is marketed as a smoking cessation aid. These drugs are dopamine reuptake inhibitors and norepinephrine reuptake inhibitors. Bupropion has also been used or is being studied to treat other disorders, including bipolar disorder, ADHD, restless legs syndrome, and obesity.

Wellbutrin XL is the extended release formulation and is taken orally once per day. Wellbutrin SR is a sustained-release formula and is taken twice per day.

This space is provided for you to share your side effects (or lack thereof) and experiences with Wellbutrin by posting a comment below.

Filed under Drug Side Effects, GlaxoSmithKline

Comments (475) | Leave a comment

The Wellbutrin XL is stabilizing in my system at 300 mg per day so that's good, however I have developed panic disorder -- independently of the Wellbutrin -- and it has really made my life hell. I guess I will find out if the Wellbutrin and exercising will cure the anxiety, but in the meantime I will talk to my psychiatrist about it. Experiencing panic attacks several times a day will surely lower your quality of life.

Posted by Adrian on October 3, 2006 11:34 PM | Permalink | Reply


Posted by Anonymous on March 24, 2012 12:06 PM | Permalink | Reply

very well said..its all about money in this country and world.

Posted by Anonymous on April 26, 2012 2:02 PM | Permalink | Reply

In response to those that feel these drugs are poison or ineffective and simply used for monetary gain - Hellooo! Asprin can be ineffective! Tylenol can be poison! Guess what? Drugs are manufactured for monetary gain. Period. There is no one magical pill that can affect every single person in the world in a positive manner. And mental health disorders are the most incorrectly diagnosed and elusive! What a surprise! Because the medical community can not simply do a blood test or cut into a part of the brain it can be very difficult to come to a correct diagnosis. Then a professional has to try and narrow down which drug will best deal with the disorder AND how your body will react to the drug. I have been personally going through this system for 20 years now with migranes, foggy thinking, depression, bi-polar depressive, anxiety, and agitation. It is really hard to have to wait and see what happens next. Whenever you have any type of question regarding your medicine and how it is affecting you PLEASE ask your medical professional! I know that they sometimes are hard to reach or even just blow you off. Sometimes they just don't realize how much something is affecting you or what your over the counter medications are. It can be very frustrating and discussions such as these are supportive. Not only do I do this for myself but I also have a child that I am working through this with. That is a lot of medical professionals to keep track of and a pretty good sized list of medications currently being taken and taken in the past. Point being: 1. There is no magic pill; 2. Ask opinions of others that are going through what you are experiencing; 3. Don't make any changes to your medicines until you have talked to a medical professional. The possible side effects of changes can be just as life altering as the effects of starting a new medicine.

Posted by Rose on June 5, 2012 6:13 PM | Permalink | Reply

shut up cant you just say something nice to people and not ramble on negatively? life is hard enough without being upset by others' words.

Posted by Anonymous on July 3, 2012 9:18 PM | Permalink | Reply

The reality is that it takes time, trial and error, to repair moods and disorders. That is not being negative....reality is the truth, and better to seek truth than empty promises. Thank you for sharing your experience. My staff of professionals agree that it takes 3-8 yrs to get the med right, as each individual responds differently. My dad improved in lexapro, my sister was too giddy on that. My mood was improved by wellbutrin...but stopping it, I am now overly hot, tingly, antisocial, and moody....may need to restart again....guess it helped more than I felt it did. It is common to believe we should be 100% repaired, but that is not reality either.

Posted by weezy8150 on July 14, 2012 10:25 AM | Permalink | Reply

The reality is that it takes time, trial and error, to repair moods and disorders. That is not being negative....reality is the truth, and better to seek truth than empty promises. Thank you for sharing your experience. My staff of professionals agree that it takes 3-8 yrs to get the med right, as each individual responds differently. My dad improved in lexapro, my sister was too giddy on that. My mood was improved by wellbutrin...but stopping it, I am now overly hot, tingly, antisocial, and moody....may need to restart again....guess it helped more than I felt it did. It is common to believe we should be 100% repaired, but that is not reality either.

Posted by weezy8150 on July 14, 2012 10:27 AM | Permalink | Reply

It does take trial and error sometimes for a long time to find the right medicine my husband has been trying everything under the sun to beat his dark depression for 6 months and is still searching. He was on wellbutrin for 1 week and now he hears a swooshing sound when he walks and moves it sucks, but when i had post-partem depression after i had my son i was practically suicide and my dr put me on Celexa and it was like a miracle pill within a week i was dancing around the house and starting to put together my sons nursery...sometimes it takes time. I have seen the effects of antidepressants work and fail, it certainly is trial and error. Hopefully we will find the right one for my husband, he is trying ambilify now i will keep posted.

Posted by candi on July 19, 2012 10:28 PM | Permalink | Reply

Hello? Wow you might want to think again as to why you have had all those symtoms for so many years. I too have been on different types of perscriptions for over 20 + years! And low and behold, come to find out that these meds that were suppose to assist in a short term amount I was kept on all these years and has caused my anxiety and other side effects. There are healthier ways to handle depression, anxiety, etc that need to as important or more so then taking a pill. As we all know exercise, activity, yoga, meditation, quite time and diet can all contribute to ones well being. so consider what they have said that it is true that each time a persciption is written...someone gets paid. The quality of life can be changed by implementing healthier way of life other than just pills.

Posted by Sandy on July 11, 2012 9:07 AM | Permalink | Reply

I have had alot of trouble with depression my whole life- I am now 45. I have tried all the things mentioned- yoga, meditation, diet, excercise. While they were really important things in my life, they did not stop my depression. Unfortunately. My friends, who are all health freaks, and do all the mentioned above, implored me to take meds for my health. While I do agree that money is a big factor in creating these meds, there are benefits to medicine. Let us remember that many people in the health industry are trying to help people- not just make a buck! So, I have tried several anti-depressants and was amazed at how well they worked, but dismayed by the side effects. I am on wellbutrin now and it seems to be great. But, I will work hard to get off of it in the next few months.

Posted by Alana Kyle on February 9, 2013 9:29 AM | Permalink | Reply

just because activities work for you, does not mean it works for everyone. please get yourself educated before commenting with ignorance

Posted by Anonymous on April 10, 2013 1:32 AM | Permalink | Reply

no, pharmasists dont get paid by perscription, they get paid hourly, and doctors are salary. so no im pretty sure its not for the money

Posted by Anonymous on April 10, 2013 1:37 AM | Permalink | Reply

Ive tried everything. Nothing works. I cant be fixed. Just want to be normalp

Posted by Anonymous on July 25, 2012 5:58 PM | Permalink | Reply

Then do that you are doing nothing more than trying to incite negative emotions in people against a drug. If it doesn't work for you so be it, don't take such a vile tone on a site where people are trying to gain understanding and relief.

Posted by Anonymous on July 29, 2012 4:39 PM | Permalink | Reply

i know the feeling. I have heard good things about Lithium

Posted by Anonymous on July 31, 2012 12:09 PM | Permalink | Reply

Hi. I've been there, and sometimes I still go there. I feel for you. I think I'll be on antidepressants for the rest of my life. I can tell you what I'm on; maybe it's something you can talk about with your doctor/therapist/psychiatrist. I started with Paxil, many years ago. Eventually, we added Wellbutrin and Lamictal. I'm on all three now. It's a good combination for me. Best of luck.

Posted by Nancy on January 11, 2013 7:45 PM | Permalink | Reply

Please do not comment on a topic you do not understand - if pharma manufacturers were in this for money, why is their whole business GOAL involve trying to help people? They could easily make more money with other professions - no BUSINESS should be ashamed of making a profit. Pharma stockholders are not anymore profitable than anyone else. Just remember - pharma employees wake up and go to work every day with the intent of making someone's quality of life better. I am a proud pharma worker as you will find most any pharma worker is. We spend our waking hours trying to help others. Can you say the same?

Posted by Julie on December 28, 2012 4:42 PM | Permalink | Reply

How do you know it isn't the Wellbutrin??!!! It is widely known to cause panic attacks in some patients. Have you talked to your doctor about this? If so and the doc sees no correlation, I would get a second opinion.

Posted by Anonymous on December 18, 2012 8:36 AM | Permalink | Reply

I have been taking Wellbutrin SR 150 for apprx 5 months with up & down results and heavy side effects. Dr upped the dosage to 300 - 2 pills a day. I went downhill very
fast. Went back to the Dr and felt like he was just concerned about pushing the drugs and $$'s. I decided I want to stop and deal with life on my own. I stoped excercise and therapy and will start back up. My question and/or concern is the correct way to stop. Cannot ask the DR cause I am not going to tell him, just stop seeing him. Can someone adivse, if I stop cold turkey, what can I expect? Thanx You

Posted by Steve on October 6, 2006 2:01 PM | Permalink | Reply

i had no side effects stopping cold turkey but i think its very important you get on something else right away, go see another dr, welbutrin is a strong drug so obviously soemthing is wrong with you if you were prescribed it idk what your symptoms are but zoloft is a good one with little side effects also buspar or ask for a ssri example celexa the first two are for depression and anxiety the second one also for that and other things get online and look up drugs for your symptoms sometimes you can tell the dr what you want to try

Posted by rachael on March 22, 2012 1:36 PM | Permalink | Reply

I would not stop cold turkey. Go down to one pill a day for a while and see how you do, and yes in the meantime find another doctor.

I feel for you, I do, and I will be praying for you. I had a doc who put me on Lexapro, but the more I took it the more depressed I got. He upped it once but that only made it worse. He kept saying, just take it, just keep taking it. Things got really bad. I went back down to one pill and eventually just quit after giving my body time to adjust. I found a new doctor and she was so much better! She really worked with me and more importantly, she LISTENED to me and my concerns!

Posted by Anonymous on June 9, 2012 2:33 PM | Permalink | Reply

I was taking Wellbutrin for about a month,,my doctor said its going to take a few weeks to kick in,,and boy did it KICK! I had to stop cold turkey,the anxiety was so bad and is still so bad I don't know the right words for it. Repetitive thoughts, over whelming sensation of I don't even know what of! I always hear on commercials ,,one of the side affects is "suicide thoughts" and I would always think,," that's so wired, I dont understand that" wweeellllll now I know ! I can't believe this little white f@&$!?g pill could cause such havoc !!! Paranoid, feeling of cant being alone,,the list goes on,just want it to stop!!! I'd rather have a broken limb than this! I just hope I haven't opened the flood gates and now that I have tapped my toe in hell ,,I can get it out without any reminents. Can any one relate???????

Posted by Anonymous on August 18, 2012 2:36 PM | Permalink | Reply

I too had the same experience on Welbutrin. I felt great for weeks then one day at the grocery store I felt very suspiscious of people and felt as if they looked evil. I am a nurse and knew that this was not normal. I decided to give it one more day and the same thing happened the next day when I was out. I called the dr and got off of it immediatly. If you read into this drug, there are a lot of people who it has helped and a lot of people who have had horrible scary side effects. Unfortunently all of these drugs have the same issues. What works for one might be a nightmare to another. So to anyone who feels as if they are going crazy while on the Welbutrin, stop taking it and the feelings should subside within a day or two thank god it has a short half life. Good luck to all!

Posted by TJ on September 19, 2012 6:03 PM | Permalink | Reply

All the old posts are gone, so I can't research back on this side effect of W XL.

I have been crying at about everything that is the least sentimental since I've been on Wellbutrin XL and ended my dose of cymbalta in mid-April.

Upped dose of XL to 450 mg 3 mo ago. Depression is better other than a relapse when sciatica from bulging disc started about 2 mo ago and pain continues and I was at wit's end from the pain and was heading into black depression again.

Cymbalta was absolutely wonderful in that I didn't cry about anything.

Anyone else going through the crying jags with W XL?

I know I need to call my Dr who had told me to wait a couple of months after upping dose to 450mg, but I was wondering if anyone takes W XL and another anti-depressant for crying?

Posted by Cheryl on October 13, 2006 10:15 PM | Permalink | Reply

I have the crying fits too. I was on Zoloft for years and couldnt cry at all. Now whenever Istart feeling highly OPTIMISTIC I cry . Im worried about church. I stopped going a while back because I could tell I was making some folks uncomfortable.
I want to go back . I wonder if not taking it that day wil help. ( I should have spipped it this morning but my depression has been frightening me of late)

Posted by True Dave on April 7, 2012 7:18 AM | Permalink | Reply

I have been having serious crying jags since starting Wellbutrin -- never had anything similar with Zoloft (which seems to have stopped working for me). I'm not taking it anymore -- can't see replacing low-energy depression with nonstop tears....

Posted by APW on April 11, 2012 4:03 PM | Permalink | Reply

Cheryl, here's the link to the old site: http://www.healthdiaries.com/blogs/pilgrim/archives/2005/10/wellbutrin_xl.html

Posted by hellothere on October 13, 2006 10:44 PM | Permalink | Reply

Hi I myself have been on zoloft and prestiq and couldn't cry for anything. I also felt no emotions what so ever. Now on wellbutrin when first starting up felt extremely emotional. I am now on wb for almost 3 weeks and that has subsided. Now I am just dizzy all the time. I am on 150 xl once a day. I haven't as of yet felt like quitting smoking and am still eating out of plavce. Can't wait until these symptoms are gone. Good luck to you.

Posted by sue souder on April 25, 2012 4:25 AM | Permalink | Reply


Thank you for the reply. I opted for cold turkey and it hasn't been to bad. I (personally) am afraid - no, terified to go through the intial phase again and deal with the thoughts and mood swings that go along with it. I just can't, at least for now. Thanx again.

Posted by Steve on October 17, 2006 2:22 PM | Permalink | Reply

Steve - I really don't think cold turkey is the best idea. I tapered off, with my psychiatrist's approval, and for a while it seemed like I was doing fine. Then suddenly one day, I went downhill. First symptom was anxiety, then came extreme depression, and then my first panic attack ever, which was one of the scariest things I've experienced, not knowing what was happening to me at the time. I started taking Wellbutrin XL again, 150mg the first week and then 300 since, but it took 2 months for it to start working again. I'm still not where I want to be, but it's worth the wait.

If you really are feeling better off it, then you may not need it anymore. But if you suddenly start to go down again, then you will need to act accordingly.

Go run daily, thats what I do every evening. It enhances the positive effects of the medication, and it's good for you anyways.

Posted by Adrian on October 19, 2006 12:17 AM | Permalink | Reply

I have read every single post and I feel like I know the regulars.

I have just started taking WBXL 5 days ago. I started on 150mg day one, and day two took 300 mg and have been since then.

My psychiatrist said the first two weeks take 150mg and then the next two weeks take 300mg and then the fifth week I have a check in appt. But I;m impulsive, and wanted to start feeling like a person again, fast...so I did the 300mg.

I feel bad bc I respect my doctor, but I;m doing "okay."

Besides the common side effects (dry mouth is really bad for me, and I haven't been eating like I normally do...hardly an appetite if any on some days, and If I want I could stay awake all night, but falling asleep is a piece of cake) I can feel it being released in my body.

It freaks me out because it is so overwhelming, I cannot control myself in any aspect.

I'm disorinted, lose focus and intrest, I;m like a vegetable until I start crying uncontrolably for the next 15 minutes.

Today(day five), I started writing down everything that I felt. I took 300mg at 645am felt my body react at 10:15am, and it seemed to go on about every three hours I have noticed. We will see if it happens around the 7-8pm hours...I am betting it will.

Like Adrian, I am also a student. I have found that when I can't be in class because of my anxiety and overwhelming feelings of saddness, I just try to focus on what I am doing at the moment.

I have had to leave two times, once today. I went to the bathroom, calmed myself down, and went back to class. I still had the feelings of the drug getting released, but it does go away after about 30-45minutes.

I know this is long, but I was freaked out (and still am) that I have to be on medication to make myself feel better and to handle my crazy life more effciently and effectivly. I had to write it, and I am glad I found this posting sight.

I have a really great support system, too. My boyfriend, mom, brother, and best friend help me out a lot. I am a very lucky girl in that aspect.

I can't wait for these four weeks to pass and for these "episodes" or "hills and valleys" to concede.

I hope that sharing my experiences --short lived so far-- will relate to someone out there like some posts have related and made me feel better about being on WBXL.

I will be checking daily.

Posted by Miranda on October 30, 2006 4:44 PM | Permalink | Reply

It is not too late for you to go back on 150mg. I was on WBXL and really liked it but I was one of the few that it made itch!! Start at a lower dose and you will see a difference with the lower dose and then up the dose when ready. The side effects are a buger when you start too high! I am now on Zoloft and I cut my dose in 1/2 and working my way up.

Posted by maria on October 31, 2006 1:56 PM | Permalink | Reply

I have tried to take WEllbutrin at least three times in the past. Last week I tried again per my physician's encouragement to counter act drowsinesss with the 30mg of cymablta I take. I took the 150XL in the am and withtin two hours I am very groggy and yawning all the time. I go from feeling very hungry to not hungry at all. My mouth is VERY dry and my heart races. I only made it four days. Has anyone else felt this strange combination of both tired and heart racing at the same time with Wellbutrin? Did it go away? Thanks

Posted by frustrated on November 9, 2006 7:36 AM | Permalink | Reply

I have to say that I have been on Wellbutrin for about 3 weeks and experience the same dryness of the mouth and my heart also races along with my mind. I have lost my appetite and have experienced bad dreams, paranoia and hallucinations. My doctor says that the meds shouldnt have that effect, but I am convinced that they are driving me crazy. I have also had episodes of deppressions and wanting to cry. I hear noises that nobody can and its making me think that I am mad. It has inculcated a horrible fear in me and I am petrified of being alone. Previous to this my doc had me on mertazapine and that made me eat non stop and I put on 7kg in 2 weeks.I have had sleepless nights and now the compounded effect of sleep deprivation is taking its toll on me. If I had known that this was the price I would have to pay, I would never have started taking them. My doc didnt even advise me on what the meds were for. The first thing she did was put me on meds and I feel that my condiditon could have been resolved in a less severe way. It has definitely changed my quality of life and has left me feeling worse than ever. I would never recommend this drug to anyone and wish that doctors would advise their patients upfront of the effects of it instead of just dispensing meds and believing that it wilol solve the problem.

Posted by Anonymous on July 13, 2012 3:49 AM | Permalink | Reply

I am on my 7th day Buprion (Zyban) my was prescribed for anxiety. I have experienced face and hand tingling and dizziness. Loss of appetite yesterday. Anyone feel these effects?

Posted by Jennifer on October 1, 2012 7:18 AM | Permalink | Reply

i feel my heart racing causing anxiety and im soooooo seepy. i feel frustrated and angry too. i take 150SR twice a day. wen i took it once a day it wasn't having those side effects but it was only helping some.

Posted by ali on October 30, 2012 7:31 PM | Permalink | Reply

I have atrial fibrillation (afib) that is normally controlled by medication. I was on cymbalta and having afib quite a lot. But, when I started 150mg of wellbutrin XL, I began to have more episodes of afib. Tried other meds that didn't work. Then, Dr and I decided to go back to wellbutrin xl and take 1/4 of a tablet for a week to see how things went. I added 1/4 of 150mg weekly all the way up to a 450mg dose and things are fine. I was able to get off of cymbalta, which the Dr and I decided could have been causing the afib episodes since I rarely have afib any longer. I do miss the lack of tearfulness with the cymbalta!

As for drowsiness, I have that at night as the amount of W xl is reducing in my body, but not in the morning. I do have dry mouth and throat, but never put 2 and 2 together that it was caused by the wellbutrin. Thought I was just not drinking enough fluids.

I had a few days on 150mg that my appetite was reduced. Dr said a study found the W XL at 450mg was the most effective in helping with weight loss. I don't have an amphetamine type loss of appetite, but if I am trying to not eat, the W XL helps.

Good luck to you.


Posted by Cheryl on November 9, 2006 10:50 AM | Permalink | Reply

I have a question about tearfulness with Wellbutrin XL.

When on cymbalta, I did not cry and found that to be wonderful after years of crying at everything. But, the cymbalta was not helping with my depression.

So, my question is if anyone is more prone to tearfulness at everything while on wellbutrin?

If so, has anyone added another anti-depressant to stop the tearfulness?

Thanks for any info you can share.


Posted by Cheryl on November 9, 2006 10:54 AM | Permalink | Reply


Thank you for posting your side effects with WB XL. I've been taking 300mg for almost 3 weeks now. I'm very concerned about the feeling of something in my throat. It feels as though I unable to clear my throat. Is this the same type of side effect you had and does it eventually go away?


Posted by Concerned on November 13, 2006 9:14 AM | Permalink | Reply

Hi Concerned,
I've been on Wellbutrin since April.

I'm not sure when the dry "cotton" mouth started, but I had noticed it getting worse lately. It feels like the tissues at rear of my throat are completely dry while the teeth area of mouth is not dry.

I found that a breath mint or gum would relieve the dryness temporarily. And, I keep a bottle of water with me at all times.

Since Fri, I have been taking a new nerve relaxer medication, lyrica, for spasming/irritated nerve in my back. I have noticed that the dryness in my throat has lessened a bit this weekend. I know lyrica says it is used to treat anxiety, too, so maybe that is helping to calm nerves in throat and back as well as decrease some anxiety.

I'm willing to put up with the dry mouth from wellbutrin, because it is not as intolerble as the deep dark depression was. Tradeoffs in everything in life, I guess. :-)

Good luck with the wellbutrin. Give it some time and maybe things will improve. Hope the dry mouth will get better.

It is the time of post nasal drip from allergies, so maybe the feeling of not being able to clear your throat is related to some allergy that you are not aware you have. I know my aunt says she feels like that w/her seasonal allergies, and I've heard her trying and trying to clear her throat.

Hang in there for the 6wks and see if things improve.
Keep a record of side effects that are bothersome and talk to your Dr at next appt.


Posted by Cheryl on November 13, 2006 11:52 AM | Permalink | Reply

Dry mouth is one of the top side effects with Wb... However some of the Wb generics are not as bad as the name brand. My experience is that most generics are pretty much the same as the NB but not with Wb - the way the drug is distributed in your system is still under patent and so some generics use a different system that does not make your mouth dry. I have issues with my sinuses when my mouth dries out because so do my sinuses.

Posted by Anonymous on July 4, 2012 5:35 AM | Permalink | Reply

It's interesting to listen to all these comments. I've been on Wellbutrin for 5 weeks now and the high anxiety has calmed down, but I don't feel much relief of the hopeless feelings. I've been wondering if it works, but maybe 5 weeks still isn't long enough. A few years ago I was on Prozac and that worked well as an SSRI, this, I'm still not convinced. Has anyone out there had to wait past 4 - 5 weeks for W to really kick in? I'm also really loosing sleep. I'm taking Immovane to put myself to sleep, and too many of them, but I'm reading that I shouldn't be taking Wellbutrin at night, as it may be stimulating me to stay awake. It was severe sleep deprivation for a full week that made me crash in the first place. I've had one dr. tell me, perhaps W isn't the best to be taking if I'm having serious sleep problems. Any thoughts?

Posted by Rick on November 13, 2006 1:37 PM | Permalink | Reply

Hi Rick,
You didn't mention your dose of Wb? It might need to be increased. Ask your Dr on your next visit or make an appt to discuss now.

As I said above, my WB XL dose is up to the maximum safe dose of 450mg. It took from April til late July to reach 450mg and then took a while for it to give me the needed relief. I have found one has to be patient with these drugs.

SR and XL in WB seem to be different for people, so not sure which one of those you are on, either. WB XL is taken once a day in the morning. SR is taken 2 or 3 times a day.

WB XL might be a better fit for the sleeping problem. Ask your Dr about it if you are not already on XL.

Good luck and keep us posted. I know how lack of sleep makes things a lot worse when depressed, too.


Posted by Cheryl on November 13, 2006 3:07 PM | Permalink | Reply


I'm glad I read your message. I was just on WB for several months. I noticed quite soon my energy go up and after a couple of weeks from the beginning of treatment my anxiousness go down. Actually, I never realized I WAS anxious till I realized how "calm" people are supposed to be (assuming this is normal). It had been causing a lots of problems in life, but I never realized I was different, so to speak. I wasn't sure if it was my imagination or if it was really the WB that calmed me down, but now I think that the WB actually helped the anxiousness.

But, even after months, the hopelessness and disinterest in life still remained, so the doctor has just prescribed Prozac instead. I'm a little scared, if I have to choose between feeling better in terms of mood and feeling better in terms of the anxiousness, but we'll see. Did you (or anyone) notice decreased anxiousness with Prozac as well?

In any case, I was only on 150mg WB, but the doctor didn't think increasing the dosage would help enough.

As for sleeping, I took WB early in morning to help sleep. The sleeping problems disappeared before 2 months were up, don't remember when. I took sleeping pills for about 2 weeks before weaning them off, and sleeping was better by then.

Good luck..


Posted by Don on November 19, 2006 4:36 AM | Permalink | Reply

I have Bipolar disorder with Panic Disorder, Generalized Anxiety, fear of death and agorophobia.

I'm...about 10 days in. So far my anxiety has completely gone away. My chest no longer hurts, when I breathe it feels like I'm actually getting enough oxygen. I hope this remains

In response to a poster, I have been on almost every antidepressant there is. None of them were calming, and none dealt with my anxiety. So far Wellbutrin is. So much I feel like I have taken a tranquilizer

My obsessive thoughts seem to have gone too, for the most part.

I have a "manic" edge to me. I have an indescribable feeling of excitement/need for adventure. I am having difficulty thinking clearly and remembering. Especially the negative thoughts, strangely. I just lost my cat recently, and I am able to space-out and forget about it, which is giving me relief.

Side effects are prominent. I feel pretty stoned/sleepy eyes and my senses are strange. Hard to describe. I get periods of extreme irritability/rage/agitation that is totally irrational. It comes and goes. I am constantly running my tongue around my mouth, which is sensitive inside. I am clenching and opening my teeth frequently. I have really bad shakes/tremors. I am grimacing occasionally. Don't want to eat/sleep. High energy compared to my norm. My sense of sight/hearing/smell have improved so much that I am putting things at half volume, which I wouldn't ordinarily be able to hear.

So far I am liking the drug, but looking forward to the "high" going away. So many side effects, but worth it for the peace of mind. The anger is scary though, super childish and I say really mean things. Definitely a manic edge to me, but far better than anxiety and major depression

Posted by lady on May 4, 2012 12:16 AM | Permalink | Reply

If the manic effects do not subside make sure you let your doctor know! The anger is always scary but it is definately a manic effect. While you may crave the 'high' you don't want the manic highs.

Posted by Rose on June 5, 2012 6:25 PM | Permalink | Reply

It sounds like you are manic. Maybe you should report these occurrences to your doctor.

Posted by Leslie on June 29, 2012 7:53 AM | Permalink | Reply

It took going up to 450mg of WB XL to get my mood to adjust. So, if the prozac doesn't work, perhaps you can ask your Dr to put you back on a higher dose of WB XL, starting at 150mg, of course, and working up.


Posted by Cheryl on November 19, 2006 7:36 AM | Permalink | Reply

ive been on Wellbutrin xl 300mg for four months. ive gained all kinds of weight and have a weight problem anyway. i have been constipated all my life and even more so now. i want to quite cold turkey. i have just been laid off and have no insurance and cant afford all the mgs. it would take to taper. HELP??

Posted by theresa on November 20, 2006 10:44 PM | Permalink | Reply

You really should talk to your Dr about the issues you are having with WB XL 300mg. Perhaps 150mg might work better. Or, the Dr can assess if you should change meds.

If you choose not to go to the Dr and to cut your dose, then you should cut to 150mg for a week before cutting completely out. (can cut the 300mg tablet in half, but the XL affect is lost when the tablet is cut)

Most Drs have lots of samples and will give to you, esp if you don't have the means to buy them now. And, the drug co will work with you to provide the meds, too, if you cannot buy them.

Good luck on finding a med that will work for you.

Posted by Cheryl on November 21, 2006 12:25 AM | Permalink | Reply

I don't know what to do.
I forgot to take my pill (WBXL) this morning and I left my pill container in my boyfriends car...I won't see him for the next twelve hours...

I'm freaking out, don't know what to do. My Dr. stressed heavily that I CANNOT miss a day.


Should I call my boyfriends job and say its an emergency or will I be alright???????

Posted by Miranda on November 21, 2006 8:20 AM | Permalink | Reply

I guess your Dr was wanting to ensure that the med works the best for you by saying you should never miss a dose.

My experience is that when I was concerned about the interaction of dyes used with CT and MRI scans with WB, my Dr said skipping the night and next morning dose would not hurt my depression and would have it out of my system enough so that is would not cause a problem with the dyes. I had to skip a dose last week cause of messing up my times for taking WB and I had no problems from skipping the dose.

But, I'm not telling you it is okay without you talking to your Dr and understanding why he was so concerned about you missing a dose. Maybe he meant he wanted it to get into your system and get to a theraputic level and missing doses would be a negative affect because it would not stay at a theraputic level.

If you think you do not want to miss the dose, then call your BF and arrange to get the med at lunchtime. But then, don't take the next dose for 12 hours.

You won't start having withdrawals symptoms or anything like that.


Posted by Cheryl on November 21, 2006 9:24 AM | Permalink | Reply


I was freaking out about it...

I didn't want to go back to how I was before WBXL just by missing one dose.

I'm going to skip today and just resume my usual 300mg tomarrow morning

(I do have a headache and I feel quite drowsy, but I'd take that over constant tears and anxiety any day)

Thank you again for your help, reassurance, and support.


Posted by Miranda on November 21, 2006 10:48 AM | Permalink | Reply


I'm a little surprised too that the doctor was so insistent that you never miss a dose. It even says in the information to just wait until the following day before continuing. That, and when switching meds, they sometimes recommend up to 2 weeks without anything to have it clear your body. I can't see one day affecting too much.

Well, I see this is 2 days later and a little late, but I guess by now you've seen that it's OK..


Posted by Don on November 23, 2006 4:00 AM | Permalink | Reply

Getting off WB...

(As mentioned before) I was on WB150 for 4 months, and the doctor switched me to Prozac because I was still so down. I stopped it a week ago, and I've never felt better! The WB lowered my anxiety, but my mood was really down. Starting the WB coincided with life problems (unrelated to why I took it), so I figured it was that. But now, suddenly, I feel happy and fine after STOPPING the WB. It could be my life issues getting better, but nothing has happened lately to affect it so much, I don't think. I feel so good I'm not sure I want to start the Prozac.

Anyone else out there have their mood get BETTER when they stopped taking the WB?


Posted by Don on November 23, 2006 4:05 AM | Permalink | Reply

its been since monday that i have taken wellbutrin and i feel great. monday i tried half a capsule and was freaking. since then i have taken nothing and have no side effects, yet, and feel great. mood good and elevated to what i would say normal levels. slowing down on running to the bathroom and taking exlax to get it all out of my system because it constipated me on top of being cronically constipated anyway. no headaches, nervousness or anything. its great.

Posted by theresa on November 23, 2006 6:24 AM | Permalink | Reply

I don't know about anyone else, but I took Wellbutrin for about 2 months. I had the WORST either...panic attack or something like that one night. I don't know what it was, but it was the worst thing I've ever felt in my life. In the past I've had my troubles with certain stimulant drugs and I'll tell you all that Wellbutrin is just a pill form of it. It may seem good to you at first, but it won't last. If it works for you then go for it, but I just want to warn you all that you gotta be careful. Make sure you don't take too much of this medicine. I hear 450 mg is the highest you should have in a day. I had a 300 mg XL tab I had to take every day and it did that to me. I don't know why and I don't care. I'm just staying as far from that pill as I can. Anyways, I just wanted to fill you in. The symptoms I had was EXTREME paranoia (like thinking I was about to die or have a stroke or heart attack), a loud ringing in my ears, a strong burning feeling in my neck, a torturous headache in my forehead, and extreme restlessness. So just be careful and good luck with this stuff if you stick with it. Just be careful.

Posted by Anon 101 on December 15, 2006 1:05 AM | Permalink | Reply

Questions! Questions! Questions!....My doctor switched me from cymbalta to wellbutrin xl 150mg about a month ago. I had horrible side effects...electric shock sensations, blurting out mean things, isolation, not feeling like myself. I read that some of you mentioned your symptoms went away, but I haven't seen these kind of symptoms anywhwere. My doct said stay on it. I called the doct (on call) on xmas eve because I felt sooo terrible & I didn't want to treat my family that way. That doc said stop taking it. After that, My doct nurse didn't return 2 of my phone calls! I want to start back, but I am scared. Has anyone else experineced these type of symptoms? I have exp these symptoms when coming off of antidep too fast.
Also, I have bad anxiety, what do your docts do for this?
Last, I requested wb for several reasons, but recently I have been on drinking binges, has WB helped anyone with cravings?
Thanks! carla

Posted by Carla on January 11, 2007 7:13 AM | Permalink | Reply

i have taken wellbutrin sr and sometimes xl when i can afford it....now since ther is a generic form of xl i was put on it...i took it this morning with my lamictal and bout an hour afterwords i felt very dizzy and couldnt concentrate and loosing my balance...i use to take the med at nite...since i have sleepin pills it doesnt keep me awake..if i took the xl at nite would it be totaly in full force by morning without the dizzness and such...and how long does the xl stay in your system? thanks for any help..email me at whymelord70@aol.com .........

Posted by James on January 20, 2007 1:45 PM | Permalink | Reply

Carla and James,

I believe you both need to talk to your Dr.

Sorry I have no advice or experience to share about your problems. I'm responding cause I didn't want you to think you are being ignored.


Posted by Cheryl on January 20, 2007 4:00 PM | Permalink | Reply

I just started on Wellbutrin about two weeks ago. The first week I felt really good. I had more energy, clearer thinking and felt like anything bad that happened in my life I could handle. On the second week I was supposed to up the dosage to two pills a day (total of 300 mg). I'm not feeling quite as good. I was very irritable yesterday and made everyone in the house miserable too. I also developed an itching but only in my hands. There aren't any bumps or redness but just severe itching. Is this something I should tolerate and it will go away? Should I reduce my dosage back to one pill a day? It's Sunday so I don't think I'll be able to contact my doctor. I do plan to talk with my pharmacist though. I wanted to know if anyone else has had this problem; how did you handle it (I should buy stock in Aveeno)? and did it eventually go away.

Posted by Jackie on February 4, 2007 6:03 AM | Permalink | Reply

I too am on week two. First week was at 150mg and then went up to 300 in week two. The side effects after going to 300 have been bad. My ears are ringing, I am dizzy all the time and have had a headache for a week. Also felt like I've had the flu (real run-down and just feel like crap overall). Deceided the possible good is not worth the bad, so I'm going back to the 150mg dose until I can talk with my Dr.

Posted by Russ on February 4, 2007 6:19 AM | Permalink | Reply

Thanks for the reply. I'm sorry you're feeling the way I am but at the same time I'm glad I'm not the only one. The headache just started this morning. I noticed yesterday that there were a few times that I stumbled but I thought it was because I was tired. You would think that upping the dosage would only make you feel that much better. I feel like laying down and crying and that's what I was taking the medicine for, to not feel that way.
I'm only going to take the one pill today and talk to the doctor tomorrow. I don't want her to say I've been impatient and have to start the two a day all over again.

Posted by Jackie on February 4, 2007 6:24 AM | Permalink | Reply

Hi Jackie-

I have been on wellbutrin for about 3 months now and I had similar reactions to what you may be feeling (you could probaly look up and find my posting on my beginning symptoms...i was freaked out when I first began too). Anyway, you need to stick it out. It will eventually get better...hopefully. I take 450mg a day because 150 and 300 were not quite enough to get me to where I wanted to be. However, if after another 2 weeks you are still irritable and have other emotional symptoms, I would definatly call your doctor.
The itching is a different story. If one is allergic to Wellbutrin; itching is what occurs. I would see if you can hold it out to about wednesday or thursday. If the itching is still there, you are allergic to wellbutrin. But this only started occuring with taking the 300mg...you may just need to lower your dose back down to 150mg to get back to normal.
Good Luck!

Posted by Miranda on February 4, 2007 6:27 AM | Permalink | Reply

Late October until middle of November (2006) I was taking Wellbutrin. I was feeling depressed and took all of my pills than didn't get a refill (quit cold turkey). I might have over-dosed, I experienced hullinations and trembling. All those things finally went away (around Christmas) but for about 3 days now Ive experienced panic attacks. Im also seeing an ear doctor for ear discomfort (any connection ?) The panic attacks are horrible, they make me feel like Im going insane and generally just give me fear in everyday life (a living hell) Does anyone know when the attacks will go away ? Or how long Wellbutrin stays in your system ? Other than the attacks my life has been great. Im no longer suffering from depression but learning to live with these Panic attacks is something impossible to handle, Ive never been so scared in my life.

Posted by Felicia on February 11, 2007 9:51 AM | Permalink | Reply

Hi everyone,
I have been on Wellbutrin XL for about five weeks now. Have tried a million other antidepressants in the past and am hoping this is THE ONE. Am currently on 300 mg a day. My biggest issue is feeling more emotional. I think it was Cheryl who mentioned that she felt like crying over everything. I find I am more easily moved to cry but also to get angry. Does anyone have any experience with this? Cheryl, did it go away? I just started a new unbelievable relationship and I don't want to be a moody cry baby (especially b/c it is so close to just being depressed). I am pretty concerned about this...I really want to be in control of my emotions, not have them control me. Should I be worried?

Would love some help.

Posted by Nicole on March 19, 2007 9:17 AM | Permalink | Reply

Nicole, that happened to me too at first -- probably for like a month if not a bit longer! Just hang in there, cuz it went away for me. In fact I was just thinking the other day that this very well may be the longest I have gone with out crying at all!

Posted by Stacy on March 19, 2007 11:59 AM | Permalink | Reply

thanks so much Stacy. It makes life so much easier to know that I am not alone. I just wasn't sure if itmeant the meds weren't working at all and I was back to crying because of depression!

Posted by Nicole on March 19, 2007 4:25 PM | Permalink | Reply

knowing i'm not alone in this has helped my peace of mind a great deal. thank you, everyone, for your comments here.

i was on well xl 150mg for 3 weeks before bumping up to the generic 300mg last week. it messed with my menstrual cycle, which made my pms totally off the charts bad. i attributed the constant crying and extreme irritability to the pms, but it's gone on too long.

i'm going to hold out for these symptoms to abate, but it's hard. i didn't feel quite this hopeless before taking the drug.

Posted by crash on March 25, 2007 11:02 AM | Permalink | Reply

Just a note to those experiencing strange side effects with Wellbutrin XL. I ended up in the ER last night because of side effects (crying, uncontrable shaking, severe anxiety, hostility and what some call brain shivers).
I was told that I had a severe allergic reaction to this drug and was told to stop taking it. Anyone else experiencing these kind of side effects should really consider the fact that they are allergic to it.

Posted by Laurie on March 26, 2007 11:14 AM | Permalink | Reply

I switched from Zoloft to Wellbutrin (tapered off Z and onto W last week, felt fine). 4 days ago I stopped Zoloft and went up to Wellbutrin XL 300 mg, as instructed by my doctor. I feel really out of it, dizzy at times, naseous and then hungry, tired and headachy. It's really hard to be at work right now. Any one have an idea of how long this will last?

Posted by rachel on March 27, 2007 11:51 AM | Permalink | Reply

Hi new posters,

Stacey - have not noticed any increased yawning and definitely not to the extent that you have it. Yawning supposedly means you are not getting enough oxygen, so you might want to have Dr check oxygen level during a yawning session.

Nicole - My crying at anything and everything has not stopped and I think I've been on W XL (not max dose)for close to a year. But, I am still having back pain and life is full of frustrations (with my physical health, trying to lose weight, and still dealing with losing both parents within 18 mo of each other and the estate stuff that follows, etc) that I feel like the crying is those pent up emotions coming out, albeit at inappropriate times. I keep delaying talking to the Dr again about another med cause I am sick of medications and want to see if I have better control after the pain is fixed.

Laurie - I have been having chills to point my teeth chatter and Dr can find no reason for that other than it could be part of menopause (better than a hot flash I suppose). So, was wondering what the brain shivers are? Hope the side effects of suddenly stopping XL will not be bad. Probably can't be too much worse than the symptoms that sent you to the ER.
Good luck to you in finding another med that will help.

Crash and those others on generic - I didn't even know the generic version was available since Drs have not mentioned it. Are you all saying that switching from W XL to generic causes the same side effects as when first starting XL? Or in your case, Crash, would the 300mg in XL have given you the same side effects as the generic?

Posted by Cheryl on March 27, 2007 12:21 PM | Permalink | Reply

I just wanted to warn you that my sister was taking Wellbutrin to stop smoking and is now in the hospital with psychosis. She was beginning to get paranoid and manic on it and she stopped taking it cold turkey. That is what sent her over the edge. It is beyond my ability to describe all that is going on with her and how devastating this is but she could easily have killed herself or someone else. She is having horrifying hallucinations and she still is not coming out of it despite antipsychotic drugs,antianxiety drugs, sleeping pills and a shot of something when she tried to escape the hospital. And still she would not sleep for the 5th day. Please talk to you doctor and SLOWLY ween yourself off of this horrible thing. She only wanted to stop smoking! She has never been crazy before and her little girl wants her mama. It is poison. We will be suing that company and may they all rot in hell.

Posted by Anonymous on March 28, 2007 5:48 AM | Permalink | Reply

Hellooo! It is called a side effect. A severe allergy. A rare one but it is known to happen. There are possible severe allergies to antibiotics, aspirin, etc. Peanuts too! It was a very bad side effect and we feel that no one should have to go through that. But we live in a lawsuit happy world, even though the possibility of the side effect was known.

Posted by Rose on June 5, 2012 6:32 PM | Permalink | Reply

Rose, do you work for the pharmaceutical company that makes Wellbutrin? You obviously have no idea what this family is going through.

Posted by Anonymous on June 11, 2012 9:56 PM | Permalink | Reply

Hi everyone,

I was on Lexapro, which is a SSRI, Seritonin something Reuptake inhibitor. It worked extremely well for four years. I requested something from my doctor because I was having extreme asthma attacks from stress and anxiety.

My then-husband walked out on me, we started divorce proceedings...it got bloody...very bloody. My pastor decided to leave the church and move on, my job was looking at closing their doors and I knew I had to move because I couldn't afford the house for my girls and I. Yes, so I was depressed, anxious and extremely stressed.

Anyway, I was on Lexapro for four years and then it slowly stopped working for me. I went to my doctor and he upped my prescription from 10 mg to 20 mg. I felt great again, then slowly it stopped working again.

I have just been put on Welbutrin and I am hearing horror stories.

I am nervous and worried about Welbutrin. I have the generic version, I don't even know whether it is XL or SR.

But I just started it yesterday. Within a half an hour of taking the Welbutrin, my mouth became cottony, I started yawning a lot and started feeling different than myself. This worries me!

Comments? My brother and his wife were both on Welbutrin for a little while and they complained of migraines, severe debilitating nausea, sleepiness during the day, etc.

Not sure I want to be on this med and don't think I want to be on Cymbalta either. Heard horror stories worse than from Welbutrin.

Comments? Advice?

Posted by Sabrina on March 28, 2007 4:03 PM | Permalink | Reply

I believe you need to talk to your Dr, who I hope is a psychiatrist who specializes in knowing the meds.

Too many differences of how W XL affects each of us. And, new info that the generic didn't go well for someone.

I do know that dry mouth is a side effect. It gets somewhat better, but have to stay hydrated. And, there's a trick to create more saliva in mouth..run tongue across top of mouth, across bottom of mouth in a circular motion around the mouth and it will create more saliva.

Good luck with the Dr.

Posted by Cheryl on March 28, 2007 4:32 PM | Permalink | Reply

Hi there,
I just started W XL at 150mg a few days agao, and am on day 3 today. The first day I had the super energized feeling but nothing too major. However, Day 2 and 3 have been unbelievable exhaustion, foggy brain and sometimes just a light tingling sensation. I would love nothing more than to lay my head down and sleep here at my work desk. Even typing this feels tiring. The minute I got home last night, I just curled up on the couch and passed out.

It seems like the majority of people experience the energized part, but I'm curious if anyone else has had this extreme fatigue? If so, did it fade? I'm willing to stick with the medication if the these side effects diminish. However, I started it to treat my depression because I was already so unproductive... this is ten times worse :P

I'm just a bit nervous as I had a horrible experience with Zoloft previously and finally got around to trying a medication again. Anyone else have similar effects or any thoughts?

Posted by elizabeth on March 29, 2007 10:33 AM | Permalink | Reply

Hi Elizabeth

My answer is not always this, although it may seem to be... but have you called your Dr and told him how the med is making you feel?

I cannot remember back to beginning of XL to know if it made me tired versus the depression still making me tired. I only got the surge of energy when I first started the med the first time around and it didn't last.

There are lots of other alternatives other than the SSRI and W XL drugs. A psychiatrist will better know all the alternatives than an internist.

Keep us posted. I'd stick it out a little longer, but I'd also call my Dr.

Posted by Cheryl on March 29, 2007 2:26 PM | Permalink | Reply

Rebecca and other generic users:

From my reading, the generic is not the same as XL as far as having extended life capabilities.

Yes, XL includes generic drug, but something about XL makes it extended life.

Generic would be more like the SR so would have a different dosing schedule rather than once a day like the XL?
Is this what your Drs are telling you?

Is that what is making a difference in how you generic users are feeling?

I'm interested cause my Rx coverage for non-generic drugs is already met in 3 mo and I can't really afford the $900+ a quarter for XL.

So, what are the Drs saying about dosing of generic and differences you might experience with generic?

Posted by Cheryl on April 1, 2007 8:17 AM | Permalink | Reply

I was just started on Wellbutrin SR, the generic form, 6 days ago. I have had really odd side effects, lethargy, light headedness, a feeling like there is a cloud/fog in my head, less ability to concentrate/focus, getting frustrated easily, crying fits, and I smoke about 1/2 a pack a day. There has been no reduction in the amount I smoke. Also, just today I started getting a head ache, which has cleared up, but right now I feel slight pressure in my head and an inability to focus, and there is a slight hearing drop. I currently take 75 mg twice a day. Any advice?

Posted by Aimee on April 2, 2007 6:29 PM | Permalink | Reply

So I wanted to say that in addition to the post that I put up about 3 hours ago, I managed to thoroughly organize all of my documents for class into separete sections. My room has been a mess for several weeks now, just paperwork from several classes piling up. Now it is pleasant to walk into. I categorized all of the paperwork by class sections, misc., reciepts, etc. I feel organized. My headache has lessened, and I just finished a reading assignment. I also realized that there has been a change in smoking. When I went to light a cigarette, I realized that I now have 13 left. Two days ago I smoked about 15. (I'd vary between 1/2-3/4, and a full pack if drunk.) Smoking 7 cigarettes today is far better than 15. Perhaps it will just lessen up. Also, that headache is gone, I feel tension on my neck and in the front of my head, but not any pain. Thanks for your help Cheryl. I'm not sure that the generic is actually different than the brand name. I believe they are exactly the same thing, or else it would have to be a different prescription drug. I guess I'm just impatient and want immediate results. I have a follow up visit on Thursday. Also, how long did it take you to feel a change?

Posted by Aimee on April 2, 2007 8:22 PM | Permalink | Reply

I have been on Wellbutrin XL for 3 years. I just switched to the generic 4 weeks ago and have gained 15 lbs in that time. Has anyone else had this? I've also been really tired and nauseous at times (no, not pregnant, got that checked). Has anyone else had this? I'm really getting concerned! Also, over the years I get paranoid at times, should I consider something for that? Besides that (and whatever is happening now), it's been working great for me.

Posted by Jenn on April 8, 2007 4:36 PM | Permalink | Reply

I started Wellbutrin SR about a month ago..last week I had severe hives..im not really even sure that's what caused the hives..but my doc seems to think so..also, I would day dream..u know like just staring off..weird...other than those ..i felt really great on the W combined with Lex...my house has never been cleaner..smoking less..and all was well. I'm trying it again in a few weeks. hopefully no hives.

Posted by sharon on April 9, 2007 4:55 PM | Permalink | Reply

I forgot to mention after a few days onWSR I was dizzy off and on for a couple days as well..but it stopped

Posted by Anonymous on April 9, 2007 5:02 PM | Permalink | Reply


I found the info on Wikipedia is very helpful regarding available dosing of each drug.

I was very surprised that bupropion comes in XL formula since it was just approved by FDA in 2003. I'd have thought Glaxco would have a patent on the re-formulation for 20 yrs, but apparently it didn't happen with this drug.

I take XL 450mg, so I can't switch to buprpion XL since there is only a 300mg dose.

Thanks everyone for sharing the info. You will note on this page that some of the mood swings are common with wellbutrin as well as placebos!

Posted by Cheryl on April 9, 2007 6:36 PM | Permalink | Reply

I started on Wellburtin Xl 150 7 weeks ago, and the doctor upped it to 300, I had the worst anixety attack ever, even the xanax wouldn't stop it. I am going back to 150, more isn't always better. My system cannot handle that dose at all. I think I will wait a while, I really just felt the welbutrin starting to work, it takes a bit longer then most, actually it is the first AD I have been on and it is for anixety, which my Doctor said it will help that also, So I am just going to wait a little longer. It may need to be the only dose I need.

Posted by Barbara on April 15, 2007 11:16 AM | Permalink | Reply

Wellbutrin works well if you are really wanting to quit smoking. I know this first hand years ago when my doctor prescribed it to me. Although I was able to quit smoking for approx. 6 months, I failed to stay on the medication due to the side affects and ended quiting the medication cold turkey and started up on the smoking again. I lost a ton of weight while on the Wellbutrin and even had co workers, friends asking me how I lost so much weight so quickly (I was taking the 150mg), but I also started experiencing heart palpitations so badly I almost got into a car accident one morning while heading into work, anxiety, panic attacks, severe ringing in the ear that I still suffer to this day. I also experienced a bout of Vertigo shortly after quiting the drug and it was not a pleasant thing to deal with for 3 days straight I had to lay in bed with my head propped and vomitted alot due to feeling severe dizziness each time I tried to stand. My blood pressure also sky rocketed at one point whileat work that I had to get dismissed immediately to go to the ER for fear I would have a heart attack, and so forth and never linked it to the Wellbutrin until now. I now take more medications to treat the side affects I suffered as a result of quiting the Wellbutrin. I've thought of going back on it again to help me quit smoking but now realize it's not worth going through all that stuff again. I just have to have the will power to try and quit smoking without drugs. Again, the drug works well when trying to quit smoking, but don't get any ideas of getting off right away after a couple of months of quiting and you'll be in some trouble. So I do beleive it's a drug you need to stay on for a long time even after you've quit smoking. Good luck to those using the drug but just be carefull. No one told me anyone this years ago when I was first given the medication, not even my doctor!!! Ask questions!! I learned my lesson. Now I monitor every medication I take and whenever I get sick which is rare I usually go take the alternative method such as vitamins, herbs, supplements, eating better.

Posted by Jeannie on April 15, 2007 3:05 PM | Permalink | Reply

I was on 300mg WBSL for 2 years and it really helped me when everything else failed. i had really bad reactions to every other type of antidepressant and i have been on them all. about a year ago i stopped taking the medication. i was feeling fine but then a lot of stress has hit me this year and my depression is very very bad. i went back on wb 3 weeks ago and my mood is really improving. i am however experiencing some strange side affects, which i do not remember from 3 years ago. nausea (i knew that would happen), restlessness (really hard to stay still), loss of appetite (not too bad i guess) but the strangest one is the fact that almost everything i drink tastes really sweet. i do not remember this at all from before. its not bad, i would much rather deal with this that the black pit that is my depressed state, but has anyone else experienced this?
Also, i went off the medication because i felt fine, but also because i moved to scotland and cannot get the doctors to give it to me for depression. they only use it for smoking cessasion. i am now having to get my mother to send my my medication and have to pay for it without insurance. Does anyone know if the UK is going to change their policy on the drug, I heard rumors and i hope it is, but i am not sure.

Posted by sarah on April 17, 2007 6:31 AM | Permalink | Reply

I've been on generic WB xl 300 mg. for about 4 months and at the same time tapering off Paxil. (I made the switch because Paxil aggravated another medical condition I have.) I took my last sliver of Paxil on 4/1. While I was tapering off, I had some mild withdrawal symptoms, but nothing severe. Now I've been off Paxil for 3 weeks, and starting about 10 days ago I have nausea, muscle aches, dry mouth, hot flashes, insomnia and no energy. These are all symptoms of Paxil withdrawal, but they are also side effects of WB. After 4 months of taking WB I would expect the side effects to be gone! I tried increasing the WB to 450 mg. several days ago and felt much worse the next day, which made me think it might be the WB. To make things worse, I'm leaving on a trip-of-a-lifetime cruise in 2 days and I feel lousy! Has anyone else had WB side effects be masked by another drug, or worsen after 4 months of using it? I would appreciate any comments that might help me know what to try next....

Posted by Sue Cram on April 17, 2007 8:15 AM | Permalink | Reply

This is to Jenn, who is experiencing weight gain and ineffectiveness on the generic XL...I have taken XL off and on for three years as well. it worked splendidly, no side effects at all. In January, my insurance co switched me to the generic. After 6 weeks of weight gain (also 15 pounds), crying, nausea, nightmares and suicidal thoughts, I made the the connection, but kept trying for a bit longer-this is not reverse placebo effect, I never doubted the generic would work. I switched back at my expense last week-the binge eating has stopped, and I am starting to feel more like myself, though not where I was. My advice, toss the generic crap in the trash.

Posted by Belva on April 17, 2007 11:44 AM | Permalink | Reply

This is to Jenn, who is experiencing weight gain and ineffectiveness on the generic XL...I have taken XL off and on for three years as well. it worked splendidly, no side effects at all. In January, my insurance co switched me to the generic. After 6 weeks of weight gain (also 15 pounds), crying, nausea, nightmares and suicidal thoughts, I made the the connection, but kept trying for a bit longer-this is not reverse placebo effect, I never doubted the generic would work. I switched back at my expense last week-the binge eating has stopped, and I am starting to feel more like myself, though not where I was. My advice, toss the generic crap in the trash.

Posted by Belva on April 17, 2007 11:44 AM | Permalink | Reply

I love this drug. I have taken Wellbutrin XL 300mg for over a year for bipolar II. Years ago I tried an earlier form of Wellbutrin for depression. I have had no noticeable side effects on Wellbutrin XL. Recently I had to stop it for two months because of clerical/paperwork problems so I couldn't get my 3 month supply sent. I immediately fell into a deep, deep depression even though I also take topamax and prozac. I was forced to withdraw from my courses this semester at school because I couldn't get out of bed or stop crying. I finally got things straightened out and received my Wellbutrin this week. I have only taken it for a few days, but already I am starting to feel a little bit alive again. I thank God for this drug. It has worked better than any of the 12 antidepressants I have tried in the past 11 years.

Posted by Heidi on April 19, 2007 5:27 PM | Permalink | Reply

Cheryl, try taking zoloft. I'm on that with wb sr. Also, I find if I'm not on birth control, I get awful pms, emotional only, no physical symptoms. Do you notice it at specific times? If so you may need some hormone therapy.

Posted by Char on April 20, 2007 7:07 PM | Permalink | Reply

I'm taking Buproprion 100mg 2x's a day. Is that the generic version of Wellbutrin? I've been taking it for 4 days. I felt the need to try out an anti-depr bcause i've been suffering from PMDD (pre-menstral disphoric disorder or severe PMS)which has been preventing me from staying on an exercise program, thus depressing me bcause I have to loose weight. Also my husband is a workoholic. He's home physically, but he's "not home". After 15yrs of trying to deal with this and be patient and understanding, I realize that its taking its toll. I'm down in the dumps.I've never taken an Anti-depr before. I'd have to say my biggest complaint is the feeling like somthing is stuck in my throat, which scares me and turns into panic. I'm a little foggy, and get a flush feeling. I don't understand, if I'm feeling down and prescribed a anti-depr, why does it have to make you feel even worse. I'm also taking Tenuate for help loosing weight. The doctor that prescribed the Buproprion also prescribed the Tenuate. I hope he's checked for drug interactions. I know a good counseling session would help us, and then I wouldn't need to take the medicine. But he's like most men, doesn't think we need it. And that the business issues will pass. I don't mean to ramble about personal issues. I know this is a posting about the Welbutrin. The throat thing definately bothers me.

Posted by Trish on April 22, 2007 6:46 AM | Permalink | Reply

Thanks Char for the heads up on estrogen effects on emotions. I'm peri-menopausal, so that could be the culprit instead of the WB. However, antidepressants are usually given to stop the emotional roller coaster of menopause.

Hi Trish,
Did your Dr or pharmacy fully explain side effects of tenuate? See http://www.drugs.com/tenuate.html
Concern is that tenuate is addictive like amphetamines and the increased heart rate/high BP can be very detrimental in the long run. Trust me, you do not want a heart arrhythmia, so be careful. And, over time the high BP can cause enomous damage to all the organs and blood vessels in your body.

I'd say it is next to impossible to know which drug is causing which side effect or if the combo of the drugs could be causing some of your symptoms.

Cotton mouth (that dryness at beginning of throat) is a common side effect of WB and for some, it goes away. You can drink more fluids which helps somewhat and you can rub your tongue around in a circle inside of mouth to create more saliva. Also, if I have to be somewhere that I cannot drink water, I use a cough drop which is a temporary fix for the cotton mouth. In my case, the cotton mouth has not gone away. But, the WB has helped me way too much to give it up for that side effect. I just live with it.

You will note by reading the above posts that people seem to have more negative and different side effects on bupropion (generic WB).

Hate to continue to say this to people, but you need to talk to your Dr about the side effects to see which med is causing what and decide if you want to pay the higher cost of WB than the generic.

As for the marital issues, I'd say you could go for counseling (psychologist or psychiatrist) without your husband and perhaps learn to accept or how to deal with his indifference to the problems.

Good luck. Keep us posted.

Posted by anonymous on April 22, 2007 8:04 AM | Permalink | Reply

hi. i've been taken wellbutrin for about 3 weeks now. i noticed a funny sensation after about 4 days.

i thought it was dizziness at first, but it's not really... it is sort of a tingling, or a surge through my nerves or something.

it happens when i turn my head, stand up or sit down and a sensation sort of starts in my chest and rises up into my head-- like dizziness, but without the loss of balance and then it goes away very quickly. occasionally it extends out into my arms.

it is not painful, not particularly pleasurable, just weird.

anyone else have this sensation? does anyone know what it is?

Posted by michelle on April 23, 2007 4:21 AM | Permalink | Reply


You said you take Tenuate for weight loss...has the drug helped at all?? I'm wondering because I have to see my doctor this week and am going to mention if he can prescribe a weight loss medication as I suffer from obesity and no diets have worked....Any info would help. Do you have to be a certain weight in order to get it??? Thanks Again!

Posted by Anonymous on April 24, 2007 10:57 AM | Permalink | Reply

On my 6th day of W XL 150. Never taken any other antidepressant. I do not feel anything. I feel inanimate, worthless and like a zombie. My speach is impaired by it, my tongue feels heavy, and like it does not respond right when I speak. How much longer until this "helps" me? Do I really need to go through this hell for a month to tell if it will help me?

Posted by Rickm on April 24, 2007 11:26 AM | Permalink | Reply

Thank You Tolipa. It is encouraging that someone with the same symptoms/issues has had success with this drug. I am just very down that I finally went for help, and it has made me feel worse (hopefully short term) and very much not myself. I will try and hang in there for one month before I decide. Did it help you when you went from 150 1x to 2x? if so how long was it before started taking it twice a day?

Posted by rickm on April 24, 2007 8:00 PM | Permalink | Reply

I was on 300 Wellbutrin for several months- had cloudy head, dry mouth, some headaches - that helped me get up and going but not helped emotionally. Dropped to 150 and went on 50 Zoloft and for 2 months now that mix seems to do it for me.

While side effects mostly tapered (I too am bummed about the appetite supression gone) I do notice increased YAWNING! It isn't as much as Stacey describes but a marked difference that was enough to cause me to check it out! So if there are any other yawners out there- at least you know there are others.

Posted by Ally on April 25, 2007 5:51 PM | Permalink | Reply

I have been on WXL 350mg for about a year now. I have lost about 20 lbs and have felt wonderful. I was always so tired--but after a week of starting it--I had so much energy and stopped all of the napping, and being so stressed out from having 9 year old twins and being in nursing school. About 3 months ago, I started on the generic, my heart has been racing over 100 BPM's (which a normal HR should be between 60 & 100). I just felt like my heart was beating out of my chest and just did not feel right. I called my Dr. last week to see if she would call in WXL 150mg so that I could decrease my dose to see if that was the problem. It has been a week now and the racing heart has stopped and I feel better, although I do feel a little bit drowsier. My Dr. wanted to see me after 3 weeks of the decreased dose--so I will see her in 2 weeks. Hopefully, she will have some insight on the generic and these horrible side effects that I was experiencing. I can't decide if I want to go back to the namebrand 300mg or just stay at the 150mg. I guess I will make my decision when I see her in 3 weeks. I will post again after I see her to let you know what she says about generic vs. name brand.

Posted by Robin on April 25, 2007 8:58 PM | Permalink | Reply

I JUST STARTED taking WB xl 150mg on Tuesday. My Dr. gave me enough samples for 14 days but told me of the generic form and that is what she prescribed. I have not had a chance to pick up the Generic RX yet but I am not ??ing if I should get the generic after reading the above comments?
Side note: I took Effexor XR for 13 months and gained 20lbs while on it,one of the reasons I am starting WBXL is becasue I hear weight GAIN is not a side effect.
I am concerned.

Posted by Just Started on April 26, 2007 5:37 PM | Permalink | Reply

to day is my 1st day taking wellbutrin sr 100 mg i'm currently on 2 different types of depression meds the other one is effexor anyway i just took the wellbutrin sr 1 hour ago and i'm feeling really tired and just want to go to bed and sleep i was wondering if anyone else felt this way befor and if it is a side effect and how long did it last ..

Posted by JANET on April 29, 2007 1:49 PM | Permalink | Reply

I am on day 5 with Wellbutrin XL. I am trying it for treatment of Adult ADHD - a new diagnosis and epiphany for me. I also take 20mg of Prozac for mild depression and an obsessive personality. The first day Wellbutrin was like a miracle! 20 minutes after I took it, my brain woke up and I felt truly alert and relaxed for the first time in my life and it lasted all day!! I can sleep just fine although only seem to need about 7 hours of rest - normally I could sleep 10 hours, nap and still get to sleep at night which is why my P-Doc thought I could use a dopamine boost and wanted to try this before stimulants.

The second day was also good but the third was a little weird. On and off my body felt like it was buzzing and I was very distracted. At 6pm I must have gotten my last "hit" from the XL tablet because my side effects worsened rapidly and I am amazed I made it home OK. I thought a couple of times about pulling over and calling my husband to pick me up because I was concerned I might have an accident, but I held it together OK.

I decided to just work from home yesterday (I am a sales rep and usually drive about 1000 miles/week) in case things got worse but I was OK - just mild/moderate brain buzz. Today I planned to be home before 6pm when my last rush comes. I was OK and felt pretty good during the day (a little of the brain/body buzz this morning) but out of the blue around 6pm (I didn't even notice the time until after) I had a massive panic attack. Good thing I hadn't been driving! Lucky for me (I guess) I have panic disorder also (although essentially recovered from that) so panic attacks are not a big deal for me and my P-Doc had warned me that I might have some while adjusting to Wellbutrin.

All in all, this has not been too bad. It is undoubtedly worth it if down the road I will ever feel anywhere close to how I felt the first day! I thought it was strange that the side effects started on the third day, but I suppose it would make sense if the drug is building up in your system. I took Prozac previously for panic disorder/obsessiveness many years ago and the depersonalization was pretty brutal for the first week compared to this. Hopefully things will not get worse. I am SUPPOSED to go up to 300mg this Sat, but I am thinking of staying at 150mg until the side effects go away and I can see whether I think an increase is necessary. After all, I have lived my whole life this way so any improvement in attention - even small - is fine by me for the time being. I will call my P-Doc and see what he thinks. I don't want to go up too quickly and be unable to drive for days....

Anonymous - nausea is a very common side effect with Wellbutrin although not one that bothers me. I have read other posts in various places from Wellbutrin users that mentioned actual stomach pain as a side effect. Does your daughter take it with food? That may help. My understanding is that side effects can last anywhere from a couple of days to a few weeks. Hopefully your daughter and I both will experience the former!

Take care all.


Posted by Amanda on May 2, 2007 7:34 PM | Permalink | Reply

I don't think that the generic XL works. I'm into my 2nd month of the generic and all of those old depressing feelings are starting to creep back in. I take 300mgs but my doctor wants to up me to 450. I'm concerned about going that high. Has anyone noticed a positive difference going from 300 to 450? And yes, I will absolutely be going back to the name brand version.

Posted by Lucy on May 3, 2007 2:27 PM | Permalink | Reply

To Anonymous.
Read the important information provided from the pharmacist. Wellbutrin should NOT be given to children under 18.

Posted by Joe on May 3, 2007 7:47 PM | Permalink | Reply

I have just started taking WB extended release roughly two weeks ago. I am currently taking 200 mg once daily. I have noticed that the past two weeks I have been taking WB, I have not been sleeping much...I am wide awake at two in the morning almost every night and usually get to sleep about three-three thirty, only to have to wake up and start my day at five thirty...I am assuming it is a side effect of WB..how long does it last though?

Posted by Kaity on May 6, 2007 1:51 AM | Permalink | Reply

I've been on Wellbutrin for about weeks; my MD started me 300mg XL...I also am taking lamictal 100mg...I am nauseated all the time with episodes of vomitting...my mouth dry a lot also...need some feed back ...thanks

Posted by Criss Winskowski on May 6, 2007 4:22 PM | Permalink | Reply

re: previous statement...I've been taking Wellbutrin 300mg XL for 3 weeks

Posted by Criss Winskowski on May 6, 2007 4:24 PM | Permalink | Reply

I was just going to post my side effect, but as I was reading down the page I noticed michelle's post (79). Michelle, be very careful. These feelings you are describing could the precursor to a seizure. These feelings can gradually get more intense and preclude a seizure. If you feel this while driving, pull over. As to my side effect, I have noticed crying listed frequently. I have had numerous tear-ups of the sentimental variety, mostly during movies or reading novels. As often as not these are "happy" tears. I have been on several anti-depressants in the past, and my 300mg XL is the best so far. Others have made me tired and emotionally "flat". I think that the extra sentimentality is a result of feeling more of everything. There is no hint of returning depression. I have been on the Wellbutrin for 4 or 5 months. The crying (I use the term crying loosely, rarely will a tear roll down) could be potentially embarrassing, but so far I have been alright. I can clamp down in public. Until this drug, I have never had happy tears before. The experience is novel and pleasant. Is anyone else experiencing this, or have the other mentions of crying been of the sad, weepy variety?

Posted by Brent on May 7, 2007 9:49 PM | Permalink | Reply

I'm glad I found this site.

My 10 year relationship ended about 18 months ago and I'm still depressed and crying everyday. I'm not the happy, easy to get along with, social person I once was. I appreciate everyone sharing their experiences with antidepressants. This is a very difficult choice.

I did a year of therapy, stopped about 5 months ago and now have returned. I posed the "Should I consider antidepressants?" question to my therapist since therpy and exercise still haven't gotten me through this. I'm afraid of the side effects and can't imagine feeling worse than I feel now as I adjust to medication. I just don't know if I can risk the emotional and physical downsides of antidepressants while hoping for a boost weeks or months down the road.

Posted by Julie on May 8, 2007 11:14 PM | Permalink | Reply

I have been on wellbutrin 150mg
for 2 weeks now and i went out and had some drinks, it made me feel like i was beyond wasted. is that normal. I bartend and told my dr. that i drink on a regular basis. Is this night out related to my medication or was it something else?

Posted by katy on May 9, 2007 7:30 AM | Permalink | Reply

My pharmacy switched my 300 XL to generic in December; I began feeling awful, but could pin-point the change to the switch to generic. I eventually just quit taking it. (Prior to the generic, the drug worked very well for me) I began taking the actual Wellbutrin XL 300mg again today. Has anyone stopped & then began taking the drug again? I am wondering if it will be effective the 2nd time around.

Posted by Anonymous on May 9, 2007 8:24 AM | Permalink | Reply

Hey anyone...

I just got a prescription for Nicotrol since the Wellbutrin gave terrible side affects. Has anyone or does anyone know of someone who has taken Nicotrol Inhaler and succeeded or either used it without any problems??? Just curious.

Posted by Annonymous on May 9, 2007 1:03 PM | Permalink | Reply

iam currently taking wb and have been for about 3 months, i was on prozac but i gained 30 lbs in about 5 months and that just made me even more depressed, iv heard that weight gain is not a side affect of wb and that you may accualy lose weight..? is this true? my dr is upping my dose from 150 to 300 and im wondering if i'll have all the side effects again that i had in the begining like a very fast heart beat, very anxious, and feeling very lost at times. if anyone knows anymore that has been on it awhile let me know .
thanx, jen.

Posted by jen on May 9, 2007 9:31 PM | Permalink | Reply

I have been back on the regular wellbutrin (300 xl) for a week now and it has been worth every penny. The way I felt taking the generic and the way I feel now are as different as night and day. I don't care what the FDA says... not all generics are created equal.

Posted by Lucy on May 10, 2007 8:23 PM | Permalink | Reply

I started taking Wellbutrin XL last fall when i started college. I had seasonal affective 2 winters ago, and i had it again this winter. Wellbutrin worked decently for most of the winter, but now that the weather is starting to get better, i have progressively started to feel worse. I have a feeling of hopelessness and most of the time i realize that i am barely breathing, or just not breathing all the way out. I take 150 mg in the morning, 150 in the evening. I didn't take one in the evening today, and at around 6 o'clock i started to feel good. Now i feel great, so i am a little confused and may go see the doc tomorow.

Posted by wayne on May 10, 2007 10:11 PM | Permalink | Reply

2 yrs ago a doctor gave me wellbutrin knowing that I was borderline epileptic with breakthrouhg seizures. I also was being diagnosed with a eating disorder. Wellbutrin made me feel really bad physically and numbed my senses. After being on it for 2 mos. I instantly passed out one morning without warning, had 2 grandmal seizures and a heart attack. Come to find out, the drug should have never been prescribed to me because of my breakthrough seizures and eating disorder. i am now disabled, live in a fog all the time and i'm not the same mentally or physically. If anyone has a chance of having borderline epilepsy or an eating disorder, please check with your doctor. This medication threw me over my seizure threshold and I crashed, thanks to the neglect of the physician and Wellbutren my life has changed forever.

Posted by Donna on May 10, 2007 10:53 PM | Permalink | Reply

I see that many people have had bad experiences with the generic form of Wellbutrin XL. Has anyone had poor experiences with the generic form of Wellbutrin SR? I just started taking it and would like to know if I should pay the extra $ for the name brand vs. the generic before I send away for my 90 day supply. Thanks!

Posted by Rachel on May 12, 2007 4:09 PM | Permalink | Reply

I saw a Psychiatrist about ADD. He prescribed me Wellbutrin because he was concerned about incidental depression which I also have. Making the switch from 150 to 300mg I have noticed myself getting hostile and edgy in most personal interactions as well having periods of more intense depression. Anybody else experience this?

Posted by John on May 13, 2007 10:51 AM | Permalink | Reply

Hi All,
So glad I found this site - I'm trying to figure out if I'm having a delayed allergic response to generic WB SR.
About 2 weeks after starting, I felt emotionally better. A couple days after that, I came down with a severe allergic reaction of horrible itchy hives over my entire body, a swollen, disfigured face, and swollen hands and feet. When my throat swelled I went to the ER. There is nothing new I've been exposed to or eaten. The only thing remotely new is the WB, but even that is 2 1/2 weeks old. I have had a similar (though not nearly as severe) allergic reaction once before, a year ago, and we never found the cause, which I hear is often how it goes with allergic responses. Has anyone experienced a delayed allergic response to WB? I have read about delayed hypersensitivity to WB, but it was described as more of a serum-sickness with fever, joint pain, etc. I didn't have either of those. The ER doc told me to discontinue the WB, just in case, but I really don't want to on such a slim chance it's the WB. help!

Posted by Laurie on May 14, 2007 7:21 PM | Permalink | Reply

Does anyone know how to contact the owner of this website?

I have emailed to editor@healthdiaries.com and to support@healthdiaries.com to no avail.

One day, after my first email 3 weeks ago, I received a response from the editor who promised to take care of a problem I had with my previous posts, but she has yet to take that action and is not responding to emails further asking for the action to be taken.

So, I am looking for the owner of the website if it is someone other than the editor.

Thanks if you can help.

Posted by Anonymous on May 16, 2007 1:32 PM | Permalink | Reply

Hi Annonymous:

If you don't mind me asking, what is your problem? maybe we here on this post can help or at least give some feedback if you're not getting the correct response? I know it does get frustrating when you really need help. I've been in that situation before.

Posted by Anonymous on May 16, 2007 1:43 PM | Permalink | Reply

I was on the maximum dose of wellbutrin for the depression that occurred because of bipolar disorder and being obese. With the meds I was able to lose 70 pounds although it didn't help me stop smoking. I tapered off some and now am not taking it at all seeing as how the reason for my massive depression also was derived from my massive weight. I'm fine so far and things are going well but that may be because of the mood stabilzer I am on as well. The only problems that I've had was hair loss and it started not too long after I started the wellbutrin. Anybody else have this problem? Please let me know because I'm anxious to find out and, if possible, fix it without hair replacement surgery. Thought it might be my other meds but none of the meds I'm taking, or have taken, have that listed as a side effect. Again, please let me know if you experience this as well so that I know what to tell the doctor at my next visit. Thanks

Posted by Julia on May 16, 2007 3:31 PM | Permalink | Reply

I was on Wellbutrin for a while to help with my smoking, although it did help with the smoking and the weight loss it didn't cause my hair to fall out. However it seems like you've been on wellbutrin for quite sometime or was. I was only on the wellbutrin for a little over 7 months and then quit when I was able to completely stop smoking. I do however have some hair loss now, since I've been on Toprol XL and Welchol. I am not sure which one is actually causin the hair loss but know for sure after reading side affects from both of them that one of them does have a side affect of "Reversible Hair Loss"....I'll have to check the meds again. It's one of the two. I think it might have been the Welchol since I recently stopped taking it and have noticed the hair loss is not as bad. I hope you are able to find the source and if not definately bring it up with your doc. It's bad enough men have to be bald but for a woman to be bald or balding!!! we just can't and won't have any of that!

Posted by Annonymous on May 16, 2007 3:54 PM | Permalink | Reply

I recv'd an email from the editor, and she has fixed the issue with my post... it was unrelated to the discussion of wellbutrin. Thanks for the offer, though.

Posted by Anonymous on May 17, 2007 4:09 AM | Permalink | Reply

You're welcome Annonymous. I'm glad someone was able to get you the help! :)

Posted by Anonymous on May 17, 2007 4:36 AM | Permalink | Reply

Have been on 300mg Wellbutrin for 2yrs but finally stopped last week due to thinning hair. My doctor said going "cold turkey" off the Wellbutrin would be okay since I'm on 10 mg of Lexapro. Am feeling awfully symptomatic for someone who is supposed to be okay.
Has anyone else experienced hair loss?

Posted by Caryl on May 20, 2007 1:41 PM | Permalink | Reply

I have been on WB for a month now. I started with the generic and after a few days felt that awful feeling that alot of you are talking about. My doctor switched me to XL (the generic one)3 days ago. I have been feeling really sleepy and weak since. My depression seems better, but I still have that hopeless feeling with no motivation for even my favorites activities. Will the WB help with the hopeless and motivation? PS: I get waves of well being that last a few minutes and go away.

Posted by Jim J on May 20, 2007 7:45 PM | Permalink | Reply

Michelle, I am also experiencing the 'zapping' feelings along with agitation, irritability and anxiety. I have been taking the Buprion 150mg XR twice daily for two weeks. These side effects are worsening day by day. I experienced similar effects when I took myself off Effexor XR after taking them for five years. I will be calling my physician in the morning to inform her that I will be discontinuing this med. My Major Depressive Disorder needs to be treated with a medication that is not cause more negative symptomology than suicidal ideation and attempts. As an epileptic, the ‘zapping’ feelings do feel a bit like a complex partial seizure episode, I hope you have contacted your physician by this time.

Posted by Jody on May 20, 2007 9:30 PM | Permalink | Reply

I have thinning hair, but mine could be attributed to peri menopause, inheritance,
beta blocker meds, so hard to say if it is the WB XL.

I started taking B-50 vitamin for hair and maybe see tiniest of improvement. One lady told me her Dr recommended biotin (sp). My vitamin had the biotin, but not at strength her Dr had recommended.

Let us know if you get any answers from the Dr on the hair loss.

To anyone:
Anyone think you are gaining weight on WB XL instead of losing as stated to be side effect?

Posted by Anonymous on May 21, 2007 11:48 AM | Permalink | Reply

I just want to say that I am so happy I found this website. I was formerly taking Paxil and wanted to try something new to see if maybe it could work alittle better. I weaned off paxil slowly b/c of certain side effects like that brain twingy feeling. (I've experienced it before when I missed a dosage of paxil and did not know what it was until I realized what I had done differently). And even my dr., who is my OB/GYN, told me I can just stop taking paxil and right away start taking wellbutrin and that I should feel fine, never once mentioning one side effect. My husband takes wellbutrin xl 150mg. and has never experienced any side effects so I just assumed that I wouldn't either. Boy, was I wrong. At first I was convinced it was Paxil withdrawal and I was not even aware that there were side effects when starting the meds. When I first started to take paxil I never experienced anything like what I have been going through. 2 days after starting Wellbutrin XL 150 mg I felt this dizziness and twitch-like feeling in my head, nausea, loss of appetite, and this wave of depression came over me. Then the non-stop crying started and feelings of just wanted to isolate myself from family and friends, which is very hard to do being a stay-at-home mom of a beautiful 12 month old girl, who all she wants is her mothers attention. At first I didn't know what the heck was going on but all I wanted to do was lay in bed and stare at the tv, waiting for the day to end, hoping to wake up to a new day and miraculously feel great and these feeling to be gone. Finally on day 5, which was last night, and starting to have doubts of this still being paxil withdrawal, I decided to research wellbutrin and that is when I found this site and I just started reading all the posts. I literally broke into tears, which doesn't take much these days, when I saw that others were experiencing the same exact feelings and side effects that I was having. I called my pharmacist first thing this morning and told her what I was going thru and I have decided, along with my dr., to stop wellbutrin and go back to paxil. Basically if it isn't broke, then don't try to fix it is how I can summarize this experience. About 3 weeks after my daughter was born I had post-partum depression and went on paxil. Within just a few days I noticed that I wasn't crying all the time. After a few weeks I felt like a new person and I could finally start to enjoy my baby and my life again. I really regret going off and switching to wellbutrin. Isn't it weird that for some people it has worked so well and some, like my husband, didn't experience not one of the side effects that I had. I don't know how some of you had the same things happening to you and stil managed to go to work. I could barely make it out of my bed, let alone my house. I really wanted to get this off my chest and say thank-you to everyone for sharing their experiences b/c it has helped me so much. I felt like I had no one to talk to that could really understand what I was going through. My husband is trying to be supportive but he doesn't understand and seems to be losing patience with me. (As I am typing this he just walked by and asked if I was feeling better b/c I just took my first dosage of Paxil, literally about 20 minutes ago and he thinks that I will miraculously feel better. He doesn't understand how antidepressants work and thinks that I should just snap out of it. I wish it was that easy!) I am really hoping that going back to paxil will work for me. I know this is a long post but I just wanted to add that just b/c wellbutrin didn't work for me doesn't mean that it won't work for someone else. That's why there are so many different antidepressants available.

Thanks again.

Posted by Elissa on May 21, 2007 1:34 PM | Permalink | Reply

I began taking Wellbutrin XL 150 mg. approximately 1 week ago. I have not noticed any effectiveness or side effects so far. Does it take awhile for this medication to get into your system? When should I notice a difference?

Posted by Frannie on May 22, 2007 8:24 AM | Permalink | Reply

Started Wellbutrin XL 300 about a week ago.1 pill per day. Had to stop immediately, broke out in terrible hives, whole body was itchy everywhere.....it was terrible!!! Have never had a reaction like this to any medication I have ever been on.Pharmacist said it will take about 7 - 8 days for it to be out of my system. Can't wait for that day to get here.

Posted by Bonnie on May 23, 2007 9:10 AM | Permalink | Reply

I've been taking WB SR for about a month now. 75mg twice a day for a total of 150mg.

I've never felt worse in my life. I started it for depression related to general unhappiness. I started to feel better - calmer - for a couple of weeks. Now, the past few days, all I want to do is cry. I feel hopeless. Like my life is meaningless. I have nobody to talk to, my doctor couldn't care less, and I have no idea what to do.

Posted by Samantha on May 24, 2007 12:11 PM | Permalink | Reply

Just got off the Wellbutrin after only 2 weeks of being on it. Developed an allergic reaction. Hands and bottom of my feet itched severly. Doctor had to call in 2 types of histimines. Thank goodness the itching stopped about an hour after I took them. I was to the point of being so miserable, I cried. Doctor told me to stop taking it after I told her what I had read on this website. So many negative comments, I'm glad I'm not taking it anymore. I went back to Prozac.

Posted by dian on May 24, 2007 12:11 PM | Permalink | Reply

Hi, I've been on Wellbutrin SR for about 5-6 weeks now and the only side effects I have experienced is a total lack of appetite/cravings (YAY!!), and feeling a tad more weepy at various times (like when Jordin won American Idol etc.). Its not bad enough for me to stop taking the meds though. My mood seems to be somehwat better too. Hopefully I won't encounter any of the side effects other people on here have experienced.

For the person who had written about going off Paxil and starting on Wellbutrin right after: the side effects you are having may, in fact be from the Paxil withdrawlas. A friend of mine had been on Paxil for a couple of years and when she started to go off it she had a terrible time, with really weird brain twinges and the like. I think it took her a good couple of months to feel better.

Also, for the person on here that mentioned having terrible pain from a bulging disc problem: I had herniated a couple discs in my neck and was in terrible, un-ending pain for about 4 months. I was ready to toss in the towel when I decided to research nerve damage. The docs all thought I had a pulled muscle but I knew it felt like nerve pain. Anyway, I found a medical site that mentioned how a lot of people with nerve pain have a lot of help from low doses of Elavil (20-50mg). I went on Elavil and it was a Godsend! The pain was totally helped. I ended up having neck fusion surgery. The Elavil was VERY sedating for me so I switched to Nortriptyline instead. It works nearly as well, but it doesn't have the sedating effect. I still have to take 20 mg of Nortriptyline at night for pain. There is a medication warning with combing the Wellbutrin with the Elavil, but at low doses its fine. I hope that helps someone.

Posted by Vicky on May 24, 2007 8:14 PM | Permalink | Reply

Anyone have any experience with WB and alcohol (moderate or excessive)? Any uncontrollable bouts of inappropriate anger? I've been on WBXL 300 for about 4 weeks now. SSRI's are NOT helpful for me and the Wellbutrin seems to help but I'm wondering how long it takes before I can be sure I've adjusted to it completely - can it take up to 2 months? My loss of appetite, anxiety and insomnia have calmed down... but I'm wondering how much of the relief from those symptoms is due to the Xanax (.5 mg) that my doc prescribed to help with those side effects.

Posted by Kelly on May 27, 2007 2:44 PM | Permalink | Reply

What a difference it makes to switch from the generic Wellbutrin to the name brand. I had been taking the generic for a couple of months and I literally thought I was losing my mind. I was feeling paranoid and one day I woke up thinking today was the day I was going to die. Not suicide, just that today was the day. I wanted to go home and write my daughter a letter and tell her everything she would need to know growing up without me. When I look back on those days, I don't really remember much else, just feeling really bad. I feel so much better since I started taking the name brand. I don't think I will ever take a generic prescription again. Anyone else been this bad or is it just me?

Posted by anonymous on May 28, 2007 5:06 PM | Permalink | Reply

Yeah I have just read through most of the comments and there is great variation from person to person. I just started taking WB XL 150mg two days ago and so far no side effects really or unless I'm missing them. I'm pretty young and kinda scared of this. I mean this will generally make you better right? Do the side effects eventually go away? I guess I'm just unsure since I've never been placed on medication. Thanks.

Posted by Vic on June 1, 2007 5:36 PM | Permalink | Reply

Hi Liz,

Yes those side effects in the beginning are normal and you should feel normal within a week. Give the meds a chance to work, I have been on wellbutrin sr 100 mg in the morning and 20 mg of prozac in the afternoon. This combination has been great for me. Just hang in for a bit longer!

Posted by Cathy on June 3, 2007 1:38 PM | Permalink | Reply

I have been taking WB XL 150's for a few months but had to switch to generic SR 150's because of insurance, I also discontinued using my Cymbalta (it just didn't seem to be doing anything...) and now I am so dizzy that I can barely function. I know that the withdraw from Cymbalta can be pretty nasty but according to my therapist I should be over the majority of it, could the dizziness be from the switch in the wellbutrin's?? Has anyone else had horrible dizziness from generic Wellbutrin SR 150? I feel like I am at my wits end, I can barely see straight and I know that I shouldn't be driving, it feels like I am perpetually drunk. HELP PLEASE!!

Posted by amy on June 4, 2007 12:12 PM | Permalink | Reply

oh and did i forgot
same question goes for alcohol but only used in appropriate means(socially,never going over board)

and then really is it worth it through all these side effects?? im 5-6 weeks in, and ive had a haedache for a weak and am light headed\sensitive to bright light

Posted by Riley on June 4, 2007 8:32 PM | Permalink | Reply

I just started WB XL again after going off of it in 2006. I don't even remember exactly why I went off of it then, but I have been having some side effects that I don't see mentioned much on this forum. I have suddenly gained about 6-7 lbs since Saturday evening, about 3 days ago. I hadn't really eaten more than I regularly do, but I can't figure out how this could happen so quickly! I'm relatively average-small in size, and it is a big shocker because some of my clothes are seeming tighter. Two other side effects I'm experiencing are constipation and dizzyness. I even feel like it takes me longer to focus on things. The constipation thing is very bad, even laxatives seem to not be working to well. My head is spinning and I can't go to the bathroom! Did anyone else experience these symptoms??? Especially the weight gain one? And does anyone have any advice on how much longer this is supposed to last?

Posted by Eileen on June 6, 2007 1:51 AM | Permalink | Reply

I'm so glad that I found you all.. I am using WB XL/450mg for 8 months -the max dose- the problem is that I recently started to experience the same things right before I started to take this medicine; drastic mood swings, feeling tired, lower back pain, hopelessness, desire of crying (all the time) So I checked w/my dr and found out that sometimes your body can become immune to the effects of the medicine. So basically even though I’m taking it every morning it is not doing anything to me. Dr. can't increase the dose because I'm already maxed out and at the beginning it was very difficult to get over the side effects so I don't think I can handle a similar case. So please tell me if anyone experienced something like this? And what was the solution to that if there was any?

Posted by nesli on June 6, 2007 12:12 PM | Permalink | Reply

taking cymbalta 60mg and 399of wellbutrinxl for smoking noticed problem in my balance falling down is it safe to take both together started with 150xl and was ok is the dose too high or dangerous together

Posted by tony on June 6, 2007 6:05 PM | Permalink | Reply

I just started taking Wellbutrin XL 150 mg 3 days ago. I am now officially scared to death. I have read all the posts and I am 2nd guessing my decision to start. I have felt a little "groggy today, but should I prepare for worse?? Help!!

Posted by Kristy on June 8, 2007 9:50 PM | Permalink | Reply

I stopped taking wellbutrin after four days. I was on the generic 150mg. I felt like crap all the time. My panic attacks were getting worse. I called my doc and he said to stop taking it and we would try something else. When I went in to see him he switched me to Effexor . I am four days into it and dont feel any of the side effects that i did from wellbutrin. its a much better drug for me

Posted by liz on June 10, 2007 6:08 PM | Permalink | Reply

I have experienced some nausea while taking WB XL, but has anyone experienced a more sensitive gag reflex? I have noticed that I'll be very hungry but can't eat because I feel like I'm gagging. Please help I've been on many medications and this one works best for me and I don't want to have to quit because I can't eat. Thanks

Posted by Ashley on June 14, 2007 7:57 PM | Permalink | Reply

Hi all,

I have terrible side effects with the wellbutrin. I am on 200 mg per day. It has helped the anxiety and depression and my energy level enormously but I have the dry mouth, sleep only two hours per night, constant racing heart, blurred vision, inability to remember things and learn new information. So.. I have been on it for four months now and the side effects are the same. I cut the dose in half and went down hill really fast so I started taking it again and I am back to the same awful side effects again. Help! My doctor doesn't know what to give me so she just says to keep taking it and it will get better but she's not the one living with all these side effects. EEEEK.

Posted by Didi on June 15, 2007 7:28 AM | Permalink | Reply

All these side effects sound very similar to what I"m going through right now with Lexapro withdrawal. The worst are brain buzz, fatique and nausea. I am still able to do my job everyday, but by the time my 8 hrs are over, all I want to do is crawl into bed. Getting a good night's rest is out of the question. My dr told me there would be no side effects from coming off this drug, and in fact, she asked me why I would want to stop taking them at all. I thought that was very irresponsible of her.

Posted by Lynne on June 15, 2007 10:53 AM | Permalink | Reply

Hi folks--I had been taking Paxil for several years but for reasons I won't go into stopped taking it recently...I stepped down gradually, however, but soon after going without it completely my old depression, anxiety, and the works came flooding back. Frustrated and frightened, I found a new doctor who prescribed Wellbutrin XL instead of placing me back on a SSRI. Since first taking it two weeks ago today, this is the first day that every waking moment hasn't felt like living hell (though I don't feel greatly improved today). The worst of it has been an overwhelming sense of gloom and doom, a super-charged anxious sensation that disaster would strike any moment. I've been crying a lot, too--I never do that. Meanwhile, my appetite has disappeared and I have to force myself to eat solid food. I've always been a champion sleeper but this drug has me wired at night, not energetic but just unable to go to sleep easily (and waking a lot when I finally do fall asleep). So far the only positive effect, assuming of course it is not a coincidence, is that I suddenly have a strong urge to read (which I once had, though it disappeared years ago), and I've been tearing through books. Anyhow, that's my tale...I sure hope it gets better!

Posted by Alan B. on June 19, 2007 2:35 PM | Permalink | Reply

I have started on Wellbutrin 150, twice a day and it has been difficult. Hand Tremmers the first week , nausea about 50% of the time for the first 6 weeks, I have been short tempered and not as kind to people as I need to be. I am determined to wait it out and make it work. I finally lost 5 pounds by the 7th week. I am in my 8 th week and still not quite right. Still a bit depressed. I was on lexapro for 4 years and it changed my life. I was only sick for 3 days and when it kiked in I was a different person. I could live with the night sweats and lack of libido because I knew why. I could not live with becoming obese, 40 pounds in 4 years. 10 months ago I started swimming a 45 min mile, 3 times a week and still gained 5 pounds! This wellbutrin has got to work and I won't give up easily.

Posted by Sandy on June 30, 2007 10:15 AM | Permalink | Reply

After 7 months on WLB xr 150, I stopped cold Turkey....I feel so much better!!! My Dr. put me on for anxiety, I felt like a vegetable, could not focus, cried easily, dizzy, could not sleep without sleeping pills, wore people out with my energy, had to force myself to eat....to some that's great... it's been 8 days since I stoppped, I am waiting for the "Big Crash" so far I feel MUCH better....I told My Dr. I wanted to stop he said NO, your doing good...well I took it into my own hands, and feel so much better, I am focused again, getting things done, I really was just watching grass grow!!!!!


Posted by Vivian on June 30, 2007 7:33 PM | Permalink | Reply

I'm new to the board...just found this site today. I am on my 3rd round of Wellbutrin. I was diagnosed with PCOS also known as Insulin Resistance- so I also take Metformin. I am actually taking the generic form bupropion which works best for me. I did have alot of the side effects mentioned- but I also noticed when I stopped "cold turkey" or stopped taking the meds at all- I gained all my weight back, my acne came back and so did all the mood swings. *Which is why I am on the meds again* I will be checking out the site often... Thanks!

Posted by Mandy on July 3, 2007 8:53 AM | Permalink | Reply

I was only on Wellbutrin (XL?) 150mg for four days to treat my depression... unfortunately, that was enough to give me one of the worst experiences of my life.

Literally the day after I started it, I began having uncontrollable crying episodes. I'd cry several times a day, usually suddenly and without much (if any) reason. I became much more deeply depressed than before, and was bombared with suicidal thoughts by day 3 or so. I thought I was going completely insane.

Needless to say, I stopped taking it. I've tried three SSRI's in the last few weeks, and none have worked - but this has been the worst for me.

Posted by Jenn on July 5, 2007 11:40 PM | Permalink | Reply

I have taken Wellbutron for 2 weeks now and I have had some nightmares and I dont normally have those (about my boyfriend getting in a motorcycle accident and it was so real.) Has anyone else had these while taking Wellburtrin?

Posted by Amber on July 6, 2007 8:39 AM | Permalink | Reply

I started taking wb 4 years ago after the birth of my daughter and I loved it from the get go. I had the dry mouth which I can live with. But what I really loved was the weight that I lost and how normal and good I felt. I stopped taking it when I got pregnant again but went back on after I finished breastfeeding and once again I had great results. Then I got pregnant a third time and for a third time after breastfeeding I started taking the wb (I am currently perscriped sr 200 twice a day I have also tried the xl which did not do the trick). This time it is just not working. I told my doctor I thought they must have changed the recipe or something. I not only gained weight I seem to be resistant to losing it despite everything I try (i.e. diet and excerise) and the nausea is lay on the floor and don't move for fear of puking bad! I don't know if this is my body getting to used to the wb for it to work or if it is the generic (from watson labs) my doctor had no advice whatsoever. But I just wanted anyone who felt similiar reactions to know they are not alone. The nausea was so bad I had to quit I have three little ones and cannot be incapacitated that way. To those for whom the drug still works congradulations for a while this drug was awesome.

Posted by Julie on July 6, 2007 9:18 AM | Permalink | Reply

I have been taking generic wellbutrin for 2 months with no bad side effects....except that last month my period was a week late and now I think that its more than a week early (or 2 weeks if you consider that it was late last month!). HAs anyone else had problems with their period???

Posted by Roxy on July 8, 2007 3:09 PM | Permalink | Reply

When I read Cheryl's post #14 about feeling something in her throat it relieved my fears of something lethal being wrong with me. My biggest problem, though, has been length of time to focus combined with an inability to remember details. My therapist says this is because the WB has reduced my "hyper-vigilance" which is part of my anxiety issue. Maybe I am not loosing my memory, just relaxing so I forget little things like my keys, or my glasses? Is this going to worsen? I have been taking WB XL 150mg for almost 3 months, for depression.

Posted by Annie on July 8, 2007 8:31 PM | Permalink | Reply


I have been on 300 mgs of Budeprion for about 6 weeks now. Started with the brand name for first 2 weeks and followed through with the Budeprion. and feel like i am in a constant fog, have no appetite, lost about 6 pounds, (not necessarily a bad thing there)and my moods have been very erratic. I feel great as long as no one upsets me then I lose it.-My coping mechanism is nil. Energy level is elevated but not overly so. Have had some thoughts of suicide, which has not ever been and issue for me. Kind of scary. As if I do not have any control of my thoughts. My ability to focus is diminished. I have been crying A Lot and have been very reactionary to everything. I was out in the sun for about 4 hours with my friends and husband the other day and when I got home I felt like crap. I felt sick to my stomach and lightheaded. I noticed that within 24 hours I developed insanely itchy skin, mostly on my back, chest, legs and arms. It is so maddening! It literally feels like there are maggots crawling under my skin and nothing seems to help, literally the itch I cannot scratch...tried the benadryl pills and itch cream..and it doesn't work. I am more photo-sensitive, headachey, and I cannot sleep what so ever. I have noticed a big difference in my mood for the better, but my husband is losing patience with me and we are currently seeing a marriage counselor. This may be very well the last resort for our relationship. I don't want to lose him and am really hoping this is it drug-wise. I was on Zoloft during my pregnancy in 2003 and continued on it until about a month ago, which is when I switched to Budeprion. Zoloft lost it's effectiveness over time and caused some nasty side effects for me,(bloating, sleeplessness,extreme weight gain- about 30 pounds!) but not near as bad as Budeprion! I am shocked to read all of these posts and the negative comments. I am kind of discouraged by it and wonder just how safe it is. I have suffered depression most of my 34 years and wonder if I should keep up with Budeprion, switch to the Wellbutrin XL brand name, or get off it and start something new. I am very concerned and really don't want to be a guinea pig anymore with all these different drugs. Any advice? Anyone else notice that A rash occurred after being in the sun for prolonged periods of time? I am now on day 2 of this itchiness and rash. I cannot stand much more of this and will be contacting my doctor immediately, now that I have read that others have had the same experience. I thought I had sun poisoning, but now I'm not too sure. I feel so alone and helpless. Please, anyone offer me some advice, as doctors don't care.

Posted by Chris G on July 9, 2007 9:49 PM | Permalink | Reply

Hi everyone!

I just wanted to add a positive. All the side effects people are describing were things I was experiencing BEFORE I went to the doctor and was diagnosed with depression. I love this drug!

I have been taking the generic WB sr 100 mg twice daily. The only side effects I had were the occasional headache which I realized was due to dehydration or lack of food because my appetite was lacking. This was a good thing since I was an emotional eater and had a weight issue. Now I feel great!

Maybe all of you have symptoms because the drug hasn't completely kicked in yet curing your depression or maybe you need to eat or drink more. I would seriously watch your hydration levels as this drug tended to dehydrate me a little but I needed to get in the habit of drinking water more anyways.

Everyone is different and reacts differently but I wouldn't discredit this drug right away without giving it a good chance.

My brother has been on this medication for 6 mths and has lost almost 30 lbs. We were both emotional eaters. I have lost 5 so far but it has only been 5 weeks. I feel MUCH better and like myself.

I know lots more positive cases but I'm sure they aren't reporting them because they have no need to complain. I wouldn't freak out from all the negatives. Again everyone is different but a small portion of people do have negative side effects. Its on the label. Maybe this forum is from the small portion.

My husband is a dentist and he said this drug is VERY common among patients so it can't be as terrible as this forum makes it out to be.

Just make sure you are in good health before you take it. And as it says on the label don't mix it with alcohol. Happy WBing!

PS There is also a big difference between the XL and the sr. I have heard a lot of negative things about the XL as far as more serious side effects, so if you are on it consider the sr. And I can't see a difference between generic and brand name. I would go with what fits your budget.

Posted by Julia on July 10, 2007 4:58 PM | Permalink | Reply

Has anyone noticed any diminution in mental acuity? I sense that I am not as sharp and verbally dexterous as I was before going on Wellbutrin and this concerns me.

Posted by David on July 13, 2007 12:51 PM | Permalink | Reply

I have the same problem after just 2 weeks. Feels like I am getting early dementia. It is awful. I also feel like I don't know who I am any more.

Posted by Anonymous on July 2, 2012 7:57 PM | Permalink | Reply

Hey, i have been taking cymbalta 60mg for almost a year now, when i started it was great, i am supposed to be on it only a while loonger, but i have noticed that i have like electric shock effects if i miss like one day, i don't know what this is, i was on welbutrin xl before this and it just made me feel detached from myself. is anyone else able to tell me that i am not crazy and this is normal or is it something more????

Posted by CASEY on July 15, 2007 4:39 PM | Permalink | Reply


I was quite relieved when I read some of your posts pertaining to the negative side effects of this drug.

I've been on XL for about a month and it has been horrible for me. I can relate to the excessive yawning. Everytime I get in my car, I feel like I am going to fall asleep and my eyes water.

However, the most disturbing side effect is the extreme anger and irrational behavior I have been experiencing. I have been yelling alot and flying off the handle. I have been getting so angry and that is very out of character for me. I feel worse off than I was without the drug.

I was simply depressed after my husband's death and this has made me feel crazy. I really can't afford to wait it out because I am the mother of a toddler. I can't continue this behavior as it is affecting my son. Has anyone else experienced this kind of adverse behavioral reaction???

Posted by Stephani on July 16, 2007 8:24 PM | Permalink | Reply

I am back on Cymbalta after a bad trial with Wellbutrin and I don't know what you mean by electric shock. However, I feel my heart beating really weird and it effects my vision at the same time. Kind of like I am going to just short out or my heart is going to stop beating!! It is a strange feeling but, all of my EKG's have come out fine. It only happens when I miss a day or two. Hope that helps.

Posted by Stephani on July 16, 2007 8:40 PM | Permalink | Reply

I have just finished switching from Effexor to Wellbutrin which was intended to increase my energy. I definitely feel more energetic, but I am extremely agitated and panicky. I have been experiencing a total loss of interest and a distaste for many things that I previously enjoyed. I seem to be triggered by everything, which is very different from my usual calm demeanor. I have read that people experience these types of symptoms for the first few months and then they settle down. Has anyone felt the way I am, and found that they felt better after sticking with it for a while? I didn't like Effexor that much, but it was a hell of a lot better then Wellbutrin is right now.

Any comments would be greatly appreciated.

Posted by abby Saltzberg on July 19, 2007 5:05 PM | Permalink | Reply

A friend of mine took this for a while. She had problems with nightmares, too. It got to the point where she prolonged going to bed at night. They reduced her dosage and the nightmares subsided slightly, but continued. They finally stopped when she switched to a different medication.

Posted by Ryan Thompson on July 22, 2007 8:05 PM | Permalink | Reply

RE: Menses (periods)

I too noticed that my menses was early this month. I was expecting it the last week of the month, and instead I got it last week (unfortunately, that's the same time my inceased libido. What timing...). I didn't think anything of it, because the point of my visit had been to replace my birth control method, and the Depo was getting out of my system. Also, I've never been dead-on regular more than a few months.
I am on the generic Wellbutrin XL. I started at 150 for 3 days, and now have been taking 2 150s for 16 days.

Posted by Lena on July 24, 2007 1:26 AM | Permalink | Reply

Hi, I am on wellbutrin 150mg/day. It has been about 4weeks now and i have just really started to feel the side effects.. I felt the dizzness in the begining but now its a whole bunch of things such as severe dry mouth, major inc urination, dizziness, diahreah and constipation...etc....As for how its been working for me....I take it for ADD unlike most of you who posted here..It has defenantly helped with my anger outbursts, i am able to focus a bit more but i think that it will take more time on it to really help me focus more..

Posted by Tami on July 24, 2007 7:10 PM | Permalink | Reply

Hi, I just stumbled upon this site and am pretty relieved. Much like any medicine there are those who react really well, really badly, or not at all to it. I'm sorry to hear about all those who've had negative experienced with Wellbutrin. I myself have been on Lexapro and Zoloft in the past. I had some small reaction with Zoloft but it seemed to go away quite quickly.
I've now been on Wellbutrin XL 150MG for just slightly over 3 weeks now, and I am PRAYING that this stuff continues having these results. Within the first week I was noticing a difference in my motivation and mood, and within 2-3 weeks I couldn't believe how different I was feeling. I wasn't anxious, I started my class again and was motivated and able to concentrate amazingly well on text reading that normally puts me to sleep(literally), and have actually been working out and just feeling much better in general. So far I haven't had any negative reactions, I hope it stays that way! My doctor and I have decided to keep on the 150MG, I'm so hoping I finally found meds that actually work and will continue to work for me.

Posted by Tina on July 24, 2007 11:47 PM | Permalink | Reply

I started taking Wellbutrin over 10 years ago, right after the birth of my twins. That pregnancy, unknowingly, caused me to develop hypothyroidism. I was entirely depressed and cried often, probably due to major post-partum as well as the change in my thyroid. I started on thyroid meds and tried several antidepressants. When I finally tried Wellbutrin, it was almost immediately as though a weight was lifted off my shoulders and the world was in color again. I know it should take a couple of weeks to take affect, but it promptly let me breathe a sigh of relief.
I'm sure that I've had many side effects over the years that I haven't attributed to the Wellbutrin, but I praised its ability to give me relief. I've tried various forms...tried both the XL and the SR, tried different dosages, tried name brand and generic. I can't say that the XL and SR made noticeable differences in the two, but the generic quickly showed its stuff by not working nearly as well. I went that route because of insurance coverage, but went right back to the name brand regardless of the cost. Unfortunately, the insurance companies compare all generics with generic antibiotics and think that any and everyone should be able to take them as though they are some broad-spectrum drug, and charge you accordingly if you dare use the name brand. Soap box...sorry. Anyway, I've gotten to the point to where I think...at what point should you try to determine if you even need antidepressants in your life any longer? When do you try to wean off of them, or do you? Well, I've bitten the bullet and have reduced my dose for a couple of weeks now. I can't say that I’ve noticed any changes in much of anything other than being oddly drained and can’t get out of bed in the morning. We’ll see…

Posted by Darlene on July 25, 2007 10:15 AM | Permalink | Reply

I have been on WBXL for four months. I haven't had problems until a week ago. The symptoms are my throat feels like its closing and like there is something in it even though I know there isn't. I feel like I have someone putting pressure on my chest. I keep thinking I'm going to have a freaking heartattack. I take something for my thyroid also. That and Wellbutrin combined shouldn't cause these problems. Only about three weeks ago the doctor put me on 450mg a day. I am wondering if I would just be better off taking 300mg. I had a urinary track infection this past weekend and had to take a antibiotic and pain meds. I am wondering if all of the medicines mixed is causing my heart to feel this weight on it and my throat closing up. I don't know but I feel like I'm going to freaking have a heartattack. I'm only 26years old. I have been annoyed easily lately and I am like a zombie at home. I don't talk to my kids, I don't play with them, I don't want to do anything or see anyone. I started taking this medicine to get rid of my depression and now I feel worse so much more worse. I have lost 15lbs but it's not worth feeling like this and being a crazy woman to my children. I haven't see many of you get any answers back from anyone. Just lots of people asking questions. I really hope someone could help me with this. I like to loose weight but I don't want to loose my mine. I need someone to write me back and help me. My doctor seems to think I have freakin' acid reflux....that ain't it. I have no burning in my chest and I've never had it before. He now has me takin' meds for my headaches, meds for my urinary track infections, meds for acid reflux, thyroid pills and the Wellbutrin. I never had these problems except for the thyroid in my whole dang life. I can't believe I even started to take the medicine. I was depressed but now it's worse. HELP ME.

Posted by Nikki on July 25, 2007 8:28 PM | Permalink | Reply

Nikki, it sounds like you should get a second opinion, or ask if you can be worked off the meds to prove to your current doctor that it is the meds as you suspect.

Posted by Tina on July 26, 2007 7:26 PM | Permalink | Reply

I have been taking Wellbutrin SR 150mgs twice a day for almost 9 months. I am bipolar 2 and borderline. I quit smoking,even quit using cocaine (which have read it helps with that too) and lost a ton of weight. I was doing well with the spending and the reckless behavior. Sleeping like a normal person and not babbling about nothing. Now over the past 2 months Im a bit manic again. Im not depressed at all and Im thrilled about it. Im not smoking or using , im binge eating now and again. but the biggest issue is the irritability. Well, it's downright MEAN and RAGE. I'm getting waves of rage rushing through me and i snap at people very easily and i feel physically uneasy. My boyfriend calls me "mean mari in the morning" for upon waking up, it truly is the worst. Im usually a sweet, kind and gentle girl, so that's why I'm thinking it's a wellbutrin thing. any ideas?

Posted by mari on July 27, 2007 11:08 AM | Permalink | Reply

Glad to see this post, and all the comments, with the exeception of a few, scare me. Have been on WB XL for one week for OCD/anxiety (prescribed by MD, who I am not sure understands) no effect yet, but diarrhea and urge to bowsel movement increasing. Any comments on this side effect. A bit embarrasing. Also, what is with this crying? Perhaps I have not been on it long enough. Help me out. I started WB because I can no longer go on with OCD/anxiety ruining my personal and social life. I though Hypnosis might help, but MD dismissed. Comments on the above?

Posted by John on July 29, 2007 4:02 PM | Permalink | Reply

Wow, I too am so glad to have found this forum and to know that some of my side effects are normal! I have been on WBXL 300 (non-generic) for about 4 months now and have had some frustrating side effects. I had my thyroid removed about a year ago and am taking synthroid. I have been losing weight by intensly exercising (60 minutes of running/walking or fast biking 6 days a week plus weights 5 days a week, plus aquafit 2 days a week and other random things). I was over 300 lbs and am currently in the low-mid 200s. I went through a really bad breakup four months ago, got tested and diagnosed with depression and was put on Wellbutrin. Suddenly my weight loss has STOPPED DEAD. It is so frustrating as I exercise like CRAZY and I stay the same no matter what I do. At first I thought it was just a plateau, but it has lasted 4 months now and I have done all kinds of things to vary my routine, so I'm starting to suspect it's the Wellbutrin, even though I know most people lose weight on it (it feels a bit unfair actually...). I wonder how much I would have gained if I didn't work out the way I do.

I have also found that I am incredibly consitpated and sweat profusely. At first I had literal hot flashes about an hour after I took the pill. Those have stopped, but I notice I sweat 3 to 4 times as much as I used to (I am SOAKED by the end of my workouts, which I never was before). I have started taking bisacodyl for the constipation, but worry about becomming "dependent" on it. Like others, I also had a lot of breakthrough bleeding a week before my period, which I also have never had before.

What's more concerning is my terrible insomnia and fatigue. I am exhausted in the evening when I get home from work and tend to be groggy during the day, but even if I manage to stay up and not fall asleep in the early evening, suddenly I can't sleep at night when I DO go to bed. I have been falling asleep around 3 am and it's really screwing up my life (almost more than the depression was in my humble opinion). If I do fall asleep when I get home, I wake up around 11 and don't usually fall asleep again until 4 or 5 am. After reading your posts, I am starting to think this may all be due to the Wellbutrin, but I've only been on for 4 months and I know my doctor wants me on for at least 6. I guess I don't really have any questions, but I'm sure the venting will make me feel a BIT better! :)

Posted by Kim on July 30, 2007 12:46 AM | Permalink | Reply

Hi all,
I was wondering if anyone knows WHY people say not to prescribe to someone who has an eating disorder? what does it do? I have previously had an eating disorder (6 years ago) and was wondering what the concern is about that... any ideas?

ps i also feel like crap... nausea, headaches, dizziness, sweating and sleeping issues, but am willing to give it a go and stick it out for 6 weeks or so. (am at end of week 2 - 150mg WXL in addition to 100mg Zoloft, which i have been taking for 12 years now)

Posted by c on August 6, 2007 4:27 PM | Permalink | Reply



Posted by Karla on August 10, 2007 12:24 AM | Permalink | Reply


Posted by Anonymous on August 12, 2007 4:00 PM | Permalink | Reply


Posted by Anonymous on August 12, 2007 4:00 PM | Permalink | Reply


Posted by Anonymous on August 12, 2007 4:00 PM | Permalink | Reply

I stopped taking Wellbutrin 300 mg a couple of weeks ago. I had weened myself off of them in the month or so previous. What I am wondering is can the quitting effect my menstrual cycle? I am usually never late but now find myself over a week late. I have had a tubal ligtation so pregnancy should be very unlikely. I was just curious if anyone else had ever had similar problems after they stopped taking Wellbutring.

Posted by anne on August 12, 2007 5:58 PM | Permalink | Reply

As a note to one of the other posters about eating disorders - specifically I think they mean bulimics. Wellbutrin can have a bad heart side effect with bulimics so they don't give it to known bulimics.

Posted by Anonymous on August 12, 2007 6:04 PM | Permalink | Reply

Oh...one more thing. The WORST month of my life was the month I took the generic for my WBXL 300. I won't make that mistake again!

Posted by Dixie on August 15, 2007 4:53 PM | Permalink | Reply

Hi All,

I have been taking wxl 450mg for about 8 weeks now. I was wondering if anyone else has this side effect:
Clintching teeth? During the day when I am concentrating on something, I realize that I am bearing down really hard on my teeth. Sometimes it is to the point of my jaws hurting. Has anyone else had this to occur?

Posted by Curious on August 18, 2007 10:08 PM | Permalink | Reply


I have been taking generic wellbutrin for 10 days and still have these awfull side effects. I feel like I am in a cloud and dizzy. I feel sad and irritable. I know side effects can last a couple of weeks but shouldn't I feel them diminish by now?

Posted by Karin on August 21, 2007 9:11 AM | Permalink | Reply

Hey folks-

Curious, i know exactly what you're talking about. WB XL has given me ridiculous driving anxiety & while sitting at a red light, i'll often realize that i've been clenching/gritting my teeth. the same thing happens at night from time to time & my jaw hurts.

here's my issue: i *was* on WB XL 300 mg for about 6 months starting in Jan. Lamictal was added in Feb. i had very few side effects the first time i was on it - some anxiety (weird b/c i'm never anxious), some tremors, insomnia, etc - but that all went away. i stopped taking WB b/c i still felt meh. i was able to get out of bed, but i still hated life.

my doc put me back on WB XL (150mg then 300mg) 3 weeks ago b/c Lamictal alone wasn't doing too great. now i'm having terrible side effects: uncontrollable shaking, insomnia, horrendous anxiety, random crying fits. i sometimes cry so much & so hard i feel like i'm hyperventilating. i don't know if i can handle this much longer. has anyone ever gone off of it & started back up? how was it for you?

whew, that was long. i think i need a nap. thanks!

Posted by Serenity on August 21, 2007 2:20 PM | Permalink | Reply

Hi everybody,

I have been taking 150mg Wb on the first week and then I get to 300mg. I have to stop it because I noticed that I was pregnant. I leave the pills without getting down the dose and I dont get any troubles by doing that, but I continue my visit to the dr. A month ago I lost my baby and I get in a really bad state, so the dr. decide to start again with the first week on 150mg and then to 300mg but for the XL. Now Im having troubles, but Im not sure if this have to do with the Wb. Im constipated, a headache that stay for hours,the feeling to have a heart stroke. Those are the worst of all. Im note sure if thishave to be because now i have the XL Wb which the dr. say it's stronger, or if are because of the pills that im taking for natal control wich is named jazmin. I need to know to see how I should proceed? pLEASE I will be very gratefull.

Posted by Dali on August 21, 2007 8:52 PM | Permalink | Reply

I am wondering if anyone has any advice for me, I posted a question on August 10th, 2007 it was # 186. I had to switch from the brand name to the generic form of Wellbutrin SR 400mg because of insurance and cost factors. My doctor said there would be no diference in the Wellbutrin SR 400mg vs. the 450mg of the XL if I wanted to switch. He said they only came out with the extended release formula because thay were running out of the patent on the SR formula. My fears are that I don't want any weight gain as I have experienced before with antidepressants. I seem so anxious at times during the day, like over stupid things. I need to relax. Can anyone relate? While I am feeling better, I don't feel calm ,as i should. I also would like to go to sleep at a decent hour. 5- 6 hours of sleep in 2 days isnt good on anyones body. Please any advice????

Posted by Concerned Karla on August 25, 2007 12:15 AM | Permalink | Reply

It's been interesting reading all the comments and Wellbutrin and Cymbalta. I was on Wellbutrin for 4 years with wonderful results and no side effects...it was prescribed because I was diagnosed with major depression. Recently it just stopped working...over a period of weeks I could just feel all the old symptoms returning. First trip to the doctor, he upped it from 300mg to the full 450mg...did nothing for me after 2.5 months. Last week he put me on Cymbalta beginning with 30mg for two weeks and increasing to 60mg after that. So far no side effects from the Cymbalta, but I did have some withdrawal symptoms from the Welllbutrin...more like a feeling that my blood sugar dropped overnite...this went on for about two weeks and would last thru half of the day. Finally has cleared up.

As far as the Cymbalta, it has taken away the depression and anxiety within the first week, but the tiredness and achiness are still present. My doctor said to give it a full two weeks for it to have it's full effects.

I have nothing bad to say about the Wellbutrin. After having been on it for 4 years, just like any other medication I am sure my system adjusted to it and like many antibiotics do, it became less effective. I only hope that I have as much luck with the Cymbalta as I did with Wellbutrin.

Posted by Paticia Netardus on August 27, 2007 1:07 PM | Permalink | Reply

It's been interesting reading all the comments and Wellbutrin and Cymbalta. I was on Wellbutrin for 4 years with wonderful results and no side effects...it was prescribed because I was diagnosed with major depression. Recently it just stopped working...over a period of weeks I could just feel all the old symptoms returning. First trip to the doctor, he upped it from 300mg to the full 450mg...did nothing for me after 2.5 months. Last week he put me on Cymbalta beginning with 30mg for two weeks and increasing to 60mg after that. So far no side effects from the Cymbalta, but I did have some withdrawal symptoms from the Welllbutrin...more like a feeling that my blood sugar dropped overnite...this went on for about two weeks and would last thru half of the day. Finally has cleared up.

As far as the Cymbalta, it has taken away the depression and anxiety within the first week, but the tiredness and achiness are still present. My doctor said to give it a full two weeks for it to have it's full effects.

I have nothing bad to say about the Wellbutrin. After having been on it for 4 years, just like any other medication I am sure my system adjusted to it and like many antibiotics do, it became less effective. I only hope that I have as much luck with the Cymbalta as I did with Wellbutrin.

Posted by Paticia Netardus on August 27, 2007 1:07 PM | Permalink | Reply

I am on generic XL, 300, and generic Zoloft 100, and have been for a few months. The only side effect I am having is sweating. Any time I even slightly think about sweating, it's buckets. So yucky. Thoughts about how to deal with it??

Posted by Amber on August 28, 2007 1:55 PM | Permalink | Reply

I have a question for all you WB users. I have been on WBXL 150mg for three days now. Anxiety seems to have quelled, but today I got extremely nauseated and threw up several times have been sick and shaky feeing all day (since about 11:30 am)I take it at breakfast. Is this a fluke or has anyone else had this happen.

Posted by Kent on August 29, 2007 5:29 PM | Permalink | Reply

I have also been prescribed Wellbutrin for Attention Deficit Disorder. I have only been on it for two weeks, but have noticed the impulsivity drastically reduced. I do not crave caffiene or sugar the way I used to. I do not have tons of thoughts swirling around in my head as much, so I am much better able to focus. SOcial interaction with people is better too, probably the result of less anxiety. I have not had side effects yet, except for a little dizziness one day. I was irritable yesterday, but could have been due to hormones. Thanks for the posts, I will definitely switch from generic if side effects occur. I would love to hear from others who are on Wellbutrin for ADD. Thanks!

Posted by Anna on August 30, 2007 7:29 AM | Permalink | Reply

I have gotten hives and wheals all over my body. My hands and feet swell. Has anyone else had this happen to them. I am not sure if it is the medication. I am on 150mg twice a day.

Posted by Bridgette on September 2, 2007 3:06 PM | Permalink | Reply

I have been taking wellbutrin xl for 3 months, 350 mg a day. Within the past 2 weeks I have begun to feel "scattered", having difficulty getting the words I want to say, feeling frustrated. Has anyone had this problem?

Posted by ROBERTA on September 2, 2007 5:11 PM | Permalink | Reply

I started taking 150mg of wellbutrin XL about 3 weeks ago. I has made all the difference in the world for me. I was bumped up to 300mg, filled the prescription, and took it for a week. What a difference. The brain fog returned, I'm lethargic and tired all the time.

They still don't have a generic for the 150mg, so I'm going back on that.

Please check the orange book from the FDA, It has a listing of all generic and brand name drugs available in the USA. Here is what I found. Wellbutrin is the brand name, brupropion is the generic, and then there is budeprion, a third generation of the brand name drug. Perhaps this is why it does not work like the other 2.

Posted by Rebecca Lee on September 3, 2007 5:29 AM | Permalink | Reply

So, has anyone had problems with body odor? I generally do not have a problem with smelly armpits, but since taking this medication I am repulsed by the smell of my own underarms! I am not sweating any more than usual, just smelly.

Posted by Sara on September 3, 2007 1:42 PM | Permalink | Reply

Has anyone had any withdrawal symptoms after having taken 300mg of WB for only 4 weeks? I don't think it's going to work for me & the side effects are too weird. If it helped, I could deal with the side effects. Not sure if I need to taper down to 150mg before quitting. I previously posted a comment on 8/24.

Posted by Cathy on September 4, 2007 4:55 PM | Permalink | Reply

wellbutrin xl 300mg works great take it the same time every moring and give it a chance it has worked so far for me, remember same time every morning and dont crush or chew the tablet you'll screw your self up bad

Posted by c on September 4, 2007 7:48 PM | Permalink | Reply

I'm taking WBXL 300mg a day, in the AM. I'm also having "postural hypotension," which is dizziness and lightheadedness when standing up. Has anyone had this side effect with WB? I dont know if it is related to the Wellbutrin.

Thanx in advance for any responses.


Posted by Steve on September 5, 2007 12:15 PM | Permalink | Reply

This may have been mentioned already and I apologize for not reading all the posts. I have been on 150mg for 4 days now and I am supposed to go up to 300 here in about 3 days but Im not sure if i'll be able to handle it. My most major side effect is what feels like blood rushing/surging/pulsing?? through my veins in my head and down my arms into my hands periodically throughout the day. What I find strange is that I can cause that sensation to occur without fail by moving my eyes from left to right very quickly. I was on Wellbutrin before several years ago but I don't think the dosage was this high and never had this problem. I am also switching to Wellbutrin from Effexor which I got off of specifically for the strange "buzzing" sensations it would cause.
So not sure if anyone has any similar experience with this or has any idea on how to reduce this sensation. It makes it very hard to concentrate during the day at work as I feel like I am only about 25% really "here".
Thank you

Posted by Michelle on September 7, 2007 8:59 AM | Permalink | Reply

I'm new to this board. In the past I've always gone to another forum. I was googling my issue and came across this page and related to a lot of things I read. I was wondering if anybody else experienced issues with taking painkillers (norco) with antidepressants. I've been on wellbutrin 300xl and lexapro 20mgs for over 3 years and was relieved from my anxiety and depression from them (with the exception of that time of the month) over a year ago I got in a car accident and had extensive nerve damage and sciatic pain so I've been on norco daily since then and been okay. However in the last 10 days or so I've been feelin extremely tired, anxious, dry mouth, dehydrated and depressed. I thought it was a bug but now I'm questioning whether or not its burnout from my meds. I was wondering if anybody has experienced this after so long and if anybody has had experience with pain meds counteracting the antidepressants. I also am on methatrexate for scleroderma that came out of remission after the accident so needless to say my body has a lot going on. I'm just wondering if the way I'm feeling is from my anxiety (since it seems kinda familiar) or if I have something else going on. Obviously, I will call my dr about all of this Monday morning but in the meantime I was hoping to hear some opinions. Ita always better to feel not so all alone. My dr had said before that I was already at kinda a high dose for lex and wellbutrin so I just feel stuck.

PS- sorry so long, I'm just lookin for somebody to understand

Posted by Melanie on September 7, 2007 9:41 PM | Permalink | Reply

I've been on wellbutrin XL, 300mg for almost 4 months now and I don't really like it anymore. The one thing it has helped with is that it took away my cigarrette cravings which is awesome!

However my depression and anxiety are not really any better and I think the reason for that is because the drug makes me so damn tired and logey all the time. I have feelings of being light headed and dizzy and all I want to do is sleep. Feeling like this can cause your anxiety and depression to heighten.

I am going to ask my Dr. reduce it down to 150mg and eventually stop taking it. It's just way too strong for me.

Posted by johnny on September 9, 2007 7:09 AM | Permalink | Reply

I am 35 years old, and have had Depression, anxiety, and some OCD issues my whole life. It got worse in my late twenties. I even had a 'breakdown' and lost a great job. However, I have no history of psychosis, bipolar, or mania. I have friends with bipolar and schizotypal disorders, and recognize their problems as different from my own.

Anyway, it took a long time to get back on track, but I have a good psychiatrist, and I work and go to nursing school. For a while I wasn't taking any meds at all and felt fine. But I was a smoker, and I couldn't quit. Zyban was not a high enough dosage.

So I am back on Wellbutrin XL 300mg a day. I desperately want to quit smoking, and it does the trick. But other problems are creeping up that are really distressing to me.

I am always hungry and have gained sooo much weight, which is making me depressed.

I had to rent 'Saving Private Ryan' a few weeks ago to try to make myself cry, because it is very hard to cry.

Sometimes I feel energized and really sleepy during the day, if that even makes sense.

My house is a mess. I mean like, a big mess. I can't seem to get motivated to clean it up.

I can't fall asleep until very late at night, and I am drowsy in the AM when I have to get to work.

But the most embarassing part is that I have been preoccupied and obssesing about exboyfriends. And I mean EXboyfriends. Guys I haven't seen in 6-10 years.

I am trying to look them up online, I sent two of them emails. This is not me. It is embarassing. If someone I hadn't talked in 5 years sent me an email I would think they were weird.

I know this sounds like I am really weak, but when I stopped Wellbutrin in the past, I started smoking again. I am being really honest here, and I know if I taper off I will be smoking a pack a day within 6 weeks.

Sometimes I think I would be better off being a smoker than making such a fool of myself. I just don't know what to do. I am too embarassed to tell my psychiatrist some of this stuff. And everyone (my family) thinks I'm doing so well, because I have excellent grades in school, a job, and friends (I just haven't invited them over for awhile.

I know I am going on and on, but the other thing is, why do I feel so much better at night? Every night I tell myself that I will get up and clean, and exercise (I used to run) and that I will cut back on the Wellbutrin and not smoke, and in the morning I feel awful again. And if you met me at school, or at work, you would think I was totally fine.
It is very complicated.

SS-New York

Posted by Samantha on September 9, 2007 9:58 PM | Permalink | Reply

I'm so glad some of you have posted about Wellbutrin's possible effects on your periods. I have been on Wellbutrin XL 150 for about 3 months now and was late during the first month and then early the next 2 months, even though I am on birth control pills and am very regular. I wondered what was going on, but never thought it could have anything to do with the Wellbutrin. For those of you with this effect on your periods, please keep us updated as to whether or not it continues.

Posted by Delilah on September 10, 2007 8:11 AM | Permalink | Reply

I'm on B XL 300mg/day. Came to this site looking for posts about clenching teeth problems and have read a few people have same issue. This is an unfortunate side effect which for me seems to be much worse in the evening or at least I notice it more in the evening. However it's a side effect I can live with since my mood has gotten a lot better (I'm bi-polar). I've been on the med for about 8 weeks. I also take prozac, lamictal, buspar, and seroquel.

Posted by kevin on September 11, 2007 7:04 PM | Permalink | Reply

I too have had an AWFUL experience with the generic (budeprion). After 3 great months of the brand my insurance decided to switch me to generic. I couldn't figure out why I was gaining and gaining weight despite running 4-5 days a week, I was so fatigued, irritable, and felt like I was in a fog. It also reaked havic on my menstural cycle. Along with awful PMS and I was three weeks late, then I had my period again in 2 weeks, then it skipped a month. All my depression symptoms had returned. After a little online research, I finally put two and two together and realized it was probably the generic wellbutrin. I had my doc write me a new brand necessary prescription. I'm now back on the brand 300XL. It's been about 2 weeks and despite a little dry mouth and stomach pains I'm feeling so much better. I have energy again and I feel like I'm happy again. I'm hoping it also can help reverse the awful weight gain I had from the budeprion as well.

Posted by robin on September 12, 2007 7:03 PM | Permalink | Reply

I recently started taking wellbutrin XL- 150 mg. Since I started taking it my resting heart rate went from 60 to around 80. I'm an athlete and work out 6 days a week. During my workouts my heart rate is up around 160. Is this normal? And, is this safe. Please let me know ASAP.


Posted by DMS on September 14, 2007 9:20 AM | Permalink | Reply

on 9/1/07 i suffered a grand mall seizure because of taking
wellbutrin. it has been documented by the hospital, my primary care doctor and a
neurologist. in the process of
having the seizure, i injured my left shoulder and have been in severe pain. i ca't function on my job. i think i am going to be forced to give up my job and file bankrupcy. wellbutrin raises your chance for seizure as you get older.
stay away from it.

Posted by Chris on September 19, 2007 3:39 AM | Permalink | Reply

my dr. prescribed me wellbutrin SR and the pharmacy dispensed the generic budeprion automatically. my first 3 days on it were AWFUL. i cried pretty much the whole time, had suicidal thoughts, extreme anxiety, could not stand to be alone anywhere, excessive sweating (soaked through my clothes) and tremors. i also had a lot of trouble focusing on ANYTHING, and for the first time in my life, I had trouble speaking. it was terrible.

i talked to my dr. and have been taking the brand name xl version for 6 days now (150mgs/day). i've had dry mouth, on and off. the worst side effect for me is my stomach pain and nausea. also ,when i had my usual cup of coffee in the morning with my wellbutrin - the combination left me in the bathroom every 15 minutes or so. i guess caffeine doesn't mix well with this drug.

on day 6, my stomach is still aching a little, but it's not too bad as long as i keep drinking some tea and make sure i have food in my stomach. other than that, i'm definitely feeling sharper, more aware, and able to concentrate on tasks at hand. i gave a presentation for the first time last night without having a panic attack!

i am going to stick with 150mgs for a few more weeks and see how i do. id say, generally, that the positives outweigh the negatives for now, but i hope more of the negatives will go away once this med levels out in my system.

good luck to all of you! get well soon! :)

Posted by anonymous on September 19, 2007 10:15 AM | Permalink | Reply

i've been taking effexor 150mg each day......then my doctor added 150 of wellbutrin xl......i have been feeling very hot and this is all above my neck. my hair at my neckline sweats and also my upper lip....its uncomfortable for those around me because i have to have a/c most of the time...i've only been on this combination for 4 weeks...will this go away....i haven't seen many posts about sweating

Posted by joan on September 19, 2007 6:17 PM | Permalink | Reply

Hi I've been on Wellbutrin 100sr for 3 weeks now. Dr. just increased me to 150. At 1st I felt better, then I started to have the spaced out feeling & sweats & chills. Now I have muscle aches, bone pain, headaches & still have the spaced out feeling. Also I have absolutely no appetite. I basically just eat junk food because it tastes good & I'm not hungry. I'm also congested so I'm not sure if I have a cold or if it's a side effect. I called in to work yesterday because I felt so miserable. How long for you all before the s/e went away?? I know for some of you it was about a month which gives me about another week to be miserable. Also, I am on the generic & thinking about switching to brand name since you all seem to think there is a difference. Maybe that would help lessen my side effects. A dose increase that is much higher is not an option since I am bipolar & my doc does not want me to go into mania. Thanks!


Posted by Jenny on September 22, 2007 6:57 AM | Permalink | Reply

I have been on Wellbutrin XL 300mgs for a month now. I am pleased with this medication so far. However, since switching my medication to morning time, I get more sleep but still not enough as I would like. I am still depressed most of the time but I am much better off now than when I had just started the medication.

Posted by Sara on September 24, 2007 7:34 PM | Permalink | Reply

Jenny, yes there is a difference between generic and Wellbutrin - I read that there are 3 subtypes of the drug and Wellbutrin had a mix of all of them? That could be totally bogus though! Wellbutrin is very expensive though, so if you can afford it, take it. As for your s/e's I never felt bone and muscle aches, but my appetite has been effected, which I kind of like because I have lost weight. Goo luck to you!

Posted by Kay on September 29, 2007 11:32 AM | Permalink | Reply

Kay: These symptoms sound like you may have a dose that's just a bit high for you. If they don't go away in a reasonable length of time, like a month or 2 and continue to bother you, or if they get worse, you may want to talk to your doctor to discuss an intermediate dosing schedule, such as alternating your current dose with the next one down.

Posted by Judy on October 1, 2007 7:08 PM | Permalink | Reply

Wow! thanks so much Judy for your reply - I think you're right about it being too high. I have been alternating my doses and I feel jittery and my headaches have subsided.

Posted by Kay on October 3, 2007 11:07 AM | Permalink | Reply

Wow! thanks so much Judy for your reply - I think you're right about it being too high. I have been alternating my doses and I feel less jittery and my headaches have subsided.

Posted by Kay on October 3, 2007 11:08 AM | Permalink | Reply

How long after you start taking budeprion might you lose weight?

Posted by Alaina on October 4, 2007 12:32 PM | Permalink | Reply

Hello all.

I have been on one dose or another or Wellbutrin for about 7 years for depression. At one point, I was on Effexor and Wellbutrin at the same time. I wound up having to take an entire week off from work to get off of the Effexor. The withdrawals from that were very tough for me, but I got through it and have been doing very well on just the Wellbutrin for some time.

For the last year and a half I have been on 150mg of XL and seemed to do well. I recently decided to stop taking it though b/c it didn't seem to be working anymore. I consulted my psychiatrist about the possibility of discontinuing my use of it a couple of months ago, and he told me that when I felt I was ready, that I could just stop taking it b/c he also felt that my depression was not so promiinent any longer. I decided to stop taking the Wellbutrin recently, and today makes three full weeks of no meds at all. I have been extremely fatigued and have not been able to sleep well. I have also been eating everything in sight.

Does anyone have any insight into the effects that I have been experiencing? I figure that they are pretty common "withdrawal" type symptoms and will most likely subside in another week or so, but I am curious to see if anyone else went through this.

Any insight/comments would be greatly appreciated.


Posted by Ali on October 4, 2007 12:38 PM | Permalink | Reply

OK, so I've posted a few times recently, but I have more questions. First, for those who have been taking WB for a long time, is there any risk of dependance, and have you had long term health complications like high blood pressure? My ultimate goal when begining this was to be able to control my depression without the use of medications. But the thought of not taking WB is so frightful to me, I just can't go back to the way I was. Also I have noticed that I have a lot more OCD tendancies, I've always been that way, but have been able to ignore it - or maybe I was too depressed. But either way, I find it strange. Has anyone had an increase in obssesive thoughts?

Posted by Kay on October 6, 2007 7:31 AM | Permalink | Reply

Hello Guys,
I wrote in a few weeks ago about an unbearable side effect. Sweating above the neck. It happens anytime, anywhere. It's very embarrassing. I would like to know if this side effect goes away? Should I stick it out? The other side effects aren't visible. Easier for me to deal with. Can someone help? This subject hasn't been dealt with very much.

Posted by Terri on October 7, 2007 9:11 AM | Permalink | Reply

I just started WB SR 150 mg on 2 days ago--today was 3rd dose.

I had a frightening episode of chest pain on one of the hundred times I woke up last night (sleep was fine the first night, horrible the 2nd night), and my chest is still tight this AM.

Anyone else get this? It doesn't appear to be a common side effect.

Posted by Elle on October 8, 2007 6:58 AM | Permalink | Reply

Hi...I have been reading this post for about an hour as I am switching to wellbutrin tomorrow from effexor. I was taking prozac for a couple of years but weight gain was more of an issue than depression. I was switched to effexor about 3 weeks ago and over the last week have had extreme nausea and headaches to the point where I can no longer deal with it. Hoping that wellbutrin will help!!

Posted by sara on October 12, 2007 7:42 PM | Permalink | Reply

Hello. I have been on Wellbutrin (generic 150 2xday) for over 10 years and have had no side effects. My doctor checks my liver enzymes and they have always been fine. I take milk thistle daily. Both my sister in laws take it and also my best friend. It has made a HUGE difference in my life. I have tried to quit several times and every time the feelings of uselessness, depression and crying returns. My husband begs me not to try and go without it. It made me feel wired and crazy for the first week but no problems since. Other than my head sweats like crazy!

Posted by Kim on October 16, 2007 3:19 PM | Permalink | Reply

I have just started generic welbuterin 6 days ago. I had been on paxil for last 7 years and felt it wasn't helping anymore. I did try welbuterin 3 years ago for 3 months (not generic) with good results. I am cash pay and could not afford it any longer. I went off paxil for 4 weeks and then started my new perscription of wb. My problem has been nausea with violent vomiting. I called pharmasist about generic vs name brand and they laughed at me. Any sugestions?

Posted by Kathleen Storll on October 17, 2007 11:30 AM | Permalink | Reply

Hey Elle, I may be wrong, but that sounds like a bad reaction to the wellbutrin. you may be taking too much or you are just in that 1/3 of the population that has a bad time with WB. You should talk to your doctor ASAP.

Posted by Kay on October 17, 2007 12:25 PM | Permalink | Reply

Re original WB vs WBSR, does the old non-sustained form cause highs and lows? (I'm thinking of taking non-sustained WB because of sleep issues).

Posted by R on October 18, 2007 2:20 PM | Permalink | Reply

I have been taking Wellbutrin XL for a week and tomorrow will increase from 150 to 300.

I also take 20mg of Celexa, have for several years...but recently plunged into a deep depression which has had me almost totally housebound. I tried Cymbalta for 10 days but had really bad side effects. I would like to stick this one out in the ever present hope of bringing myself out of this depression and back into life again.

I have had congestion this whole week with achiness and am wondering if that is a Wellbutrin side effect. I am also constipated and really hate that- have NEVER had that problem in 54 years! I know it is too soon to see the positive effect so basically just am wondering if these side effects generally pass after a while.

Thanks for all the thoughtful answers here.

Posted by Meg on October 19, 2007 12:28 AM | Permalink | Reply

I have been taking Wellbutrin XL 150 for about 3 weeks now. I take it early in the morning before I go to work. Lately I have been noticing that I'm having these weird "spacey" feelings with a slight headache in the evenings. I'm wondering if maybe the medication is wearing off by the evening. Has anyone experienced these feelings? I was wondering if maybe I should increase my dosage to 300mg.

Posted by Barb on October 19, 2007 8:32 PM | Permalink | Reply

I am on a combination of wellbutrin and lamictal and I feel great. I want to add a general comment to all these posts--


I think we look towards other people to make sure our reactions are 'normal'-- if we are having reactions, they are normal for US! And through any kind of healing the most important thing is that we get to know our INDIVIDUAL bodies. The more we know ourselves, and trust ourselves, the better we will feel. If a drug doesn't work for us, we should find a very good doctor who can tweak it. Listening to other people's experiences can be helpful ONLY if we are building a more clear understanding of ourselves with compassion.

I do find it helpful to talk to my parents and my sister about how they respond to different stimuli-- I understand the similarities and differences between our bodies, and so can make sense of it all.

We are all working very hard to stay healthy, and we all deserve to be happy!

But we must never forget therapy and all kinds of other insight work. Sometimes we need to sob, need to release all the pent up sadness and anger. We cannot become healhty without gently examining our delicate psyches, and we need good people to help us with that.

A trusted therapist, nice friends and family and a good psychiatrist are essential!

With love,

R in NYC

Posted by RC on October 21, 2007 9:24 AM | Permalink | Reply

I have been on Wellbutrin for 5 weeks. I had been on Celexa previously, for almost a year, but it caused me to be nauseated, so I asked for a change. BIG mistake. Although Wellbutrin does curb my appetite, I have become an emotional basket case. I cry all the time, any where I am (at Starbucks, the grocery store, work...EVERYWHERE!). I also have become an irritable and aggressive B@#$%^&. I have had several people tell me they are not sure what is wrong with me but that I am not the same person I used to be. Even my own daughter doesn't know me and tells me she would rather me be sad then to be yelling and screaming (sometimes at people I dont even know). I am sure Wellbutrin works for some, but for me it just caused me to be totally irrational and out of control.

Posted by Jackie on October 21, 2007 12:54 PM | Permalink | Reply

I have been on Wellbutrin XL for about 3 months, at 150 mg. It started to relieve my depression symptoms pretty quickly, and until recently, I felt great about it, even lost a few pounds. I do have the side effect related to taste, but different than picturegirl wrote about. I have a bad taste in my mouth all the time. I also seem to be sweatier - my old deodorant/anti depressent doesn't do the trick!

But I write now to ask how you know if you need to up your dose? For the last few weeks, I have been feeling poorly again, with crying spurts and general depression. I have been under more stress, but I am wondering if the real problem is that my body adjusted to the 150mg, and perhaps I need more? I'm also GAINING weight now - is that possibly related to the Wellbutrin? Does your body adjust after a while and you need more to achieve the same affects?

Posted by KK on October 25, 2007 4:44 AM | Permalink | Reply

I've been WXL 300mg since September and was having usual side effects like dry mouth, loss of appetite & sweating. However about 2 weeks ago the Dr upped my does to 450mg because I was going thru some personal problems and 300mg didn't seem like they were doing the job. I feel much better but the one thing that I have noticed is the bitter taste in my mouth. I mean really bad, I have to either put a mint in my mouth or chew gum all day long. Has anyone else noticed this problem?

Posted by Sandi on October 28, 2007 10:18 AM | Permalink | Reply

Hi-- I've been on Wellbutrin for a while now, and recently with an increase in dosage, I've experienced weight gain and hair loss. Any one else had those side effects?

Posted by duck on October 31, 2007 2:30 PM | Permalink | Reply

I have been taking 150 mg Wellbutrin XL (1x am) for 9 days.
It was prescribed to treat depression and to help me wake up. So far I have felt tired, weak, groggy, and disconnected. My depression has not improved either.

My question is:
Has anyone had similar effects which subsided with time? If so, how long did it take?

Thank you in advance for you help.
I understand everyone reacts differently to medication. I guess I am just looking for some hope and inspiration to keep taking my meds.

Posted by Student on November 11, 2007 11:08 AM | Permalink | Reply

I was put on Wellbutrin a number of years ago to either compensate for sleepiness cause by taking pain meds for back trouble or for possible depression. I really haven't had problems unless it caused me to be sleepy (which I don't think it did - on 400 mg/day SR) until recently. Just a little while before I was put on Wellbutrin, I had half of my thyroid out for Thyroid cancer. I was put on thyroxine and told that my "levels were normal." Recently I was diagnosed with sleep apnea and found that hypothyroidism can cause the sleep apnea. The second Thyroid doc I had also stated that "levels were normal." I did some research and asked for a T3 drug. Second Doc passed me to an endocrinologist. I was given T3 (in my terms a miracle pill) and all of the sudden I had energy again and I am appearing to sleep much better. The problem is now I have terrible problems with dry mouth. A doc told me that was just because of my sleep apnea, but that doesn't explain having the dry mouth all day long. Cytomel (T3) does not have a side effect of dry mouth and that is the only new drug I'm taking. Sorry to ramble, but had to layout the background. Here is the question. Is it possible since I was hypothyroid that I wasn't metabolizing the Wellbutrin (generic) fully, but now that I have adjusted my metabolism I am now metabolizing the drug and having terrible dry mouth?

Posted by Beau on November 11, 2007 5:16 PM | Permalink | Reply

i take wellbutrin xl 300 mg.

i've noticed my hair thining- bald spots. i used to have a really thick set of hair, but now it just looks 'lifeless.'

i heard 2500 mcg of Biotin helps.

Posted by Raymond on November 13, 2007 12:22 PM | Permalink | Reply

I miss me...WB has turned me into a zombie and I'm more depressed than before. I've only been on it for 5 days, but I don't think I want to see if it works out after reading these posts. One of my major complaints about WB are the constant hallucinations. While mild they make me anxious, agitated and a little paranoid. I don't have much in the way of visual hallucinations, mostly hearing sounds and perceiving them to be threats and smelling odd smells that don't exist. I'm also emotionally "flat", have no interest in anything and I'm shaky and feel very cold most of the time. And I've never had anger issues before, but now I don't trust myself around anyone. I just want to be alone. I was told this medication would work for Seasonal Depression and help me to quit smoking, but right now I miss how I normally feel. Has anyone else had hallucinations? Do they go away or should I quit taking WB right away? It doesn't make sense to suffer for a full month when my seasonal depression only lasts for 4 months anyway - does it make sense to hang in there and see what happens? After reading these postings, if WB doesn't work for me, I'll go back to being un-medicated. It doesn't seem so bad now.

Posted by Andrea Searcy on November 17, 2007 1:40 AM | Permalink | Reply

To add to my comment above, I'm taking generic 100mg SR twice a day. After only 5 days, do I have to worry about withdrawals if I quit?

Posted by Andrea Searcy on November 17, 2007 2:21 AM | Permalink | Reply

My dose was just increased fro 75 mg per day to 200. I'm having trouble breathing and feel like I'm having a heart attack. Bitchie as all hell. Any similiar experiences?

Posted by Kimberly on November 17, 2007 6:34 PM | Permalink | Reply

HI, I started welbutrin 2wks ago didn't experience any side effects on 150mg the first week started to take a 2nd. dose of 150mg and after 4 days I developed a ringing in my ears. I stopped for 3 days and still have it. My doctor wants me to cut back and go to 1 pill a day for a week and see if it stops. I feel better my energy level is up and it has made a difference in a short time, but I can't live with the ringing in my ears and I'm afraid it won't go away. Has anyone experienced this? thanks

Posted by stacy on November 19, 2007 8:24 PM | Permalink | Reply

I am in my 3rd week of taking Welbutrin SR. First 2 weeks, 1 tablet a day. After 2 weeks, 2 a day. I still cry a lot every day and I can't even tell if it's working or not. I am in the middle stage of a very painful divorce and I think my wife was seeing someone else because I have ED.Anyway, everytime I think of her being with someone else I begin to cry. We have a 6 yr. old and it hurts not to be able to put her to bed anymore.Thanksgiving and Christmas is coming up and I am very afraid that my depression will be more painful than now. Someone please tell me what to do. I'm so tired of crying. Can't take much more.
William C.

Posted by William Childs on November 20, 2007 5:28 AM | Permalink | Reply

Has anyone experienced muscle/joint pain? My left arm feels fine until I extend it to the left and back such as when closeing a door on your way out of a room. The pain is pretty bad but disappears as soon as I bring my aarm back. I went to a chiropractor for a number of treatments which did no good. It seems if I stretch in the direction of the pain, it gets better. Recently I have begun experiencing pain in my right hand when I make a fist, this pain feels more like it originates in my joints more than my muscles, however it radiates into the muscles as well. Help.....

Posted by Jeff on November 21, 2007 6:42 AM | Permalink | Reply

I started with 150mg of XR on the advice of my therapist & doctor about 3 weeks ago. I didn't notice any difference in how I felt. I am not clinically depressed, but I have been feeling crummy about a potential divorce. This week Dr. said to bump it up to 300mg. Within 3 days, my anxiety is up, I can't sleep, even when taking the meds in the morning. My short term memory is bad and I feel like I'm not in control of my thinking process. My mouth has a constant strange taste that brushing or mouthwash won't cure. Maybe taking it longer will change things, but I am already cutting back to 150mg/day in an attempt to re-stabilize myself. I have some very critical decisions to make in the next few weeks and I certainly cannot do that feeling like I currently do. I think I felt in more control BEFORE taking the Wellbutrin.

Posted by Jimmler on November 21, 2007 12:54 PM | Permalink | Reply

I have taken Prozac since 1987. Off during pg. one that lasted for 9 months and twins.
During this time I tried Wellbutrin once, and was very aggitated and hard to be around. I went back to prozac.
I have gained 20 plus lbs during this time. I exercise 1 hr plus weights daily and eat healthy. Wt should not be a problem. After researching prozac and wt gain I decided to try Wellburtin XL 150 again. However, 20 years ago I was bulimic, so I am a counsious of the problem with higher dosages of this drug and seizure.

I hope that I can deal with my depression with this drug and xanex if needed for anxiety.

Please give any advice, comments...

So far so good. I am using xanex for anxiety as needed. I hope that this will help me lose the

Posted by Maggie on November 21, 2007 4:03 PM | Permalink | Reply

i have been on xl for about 8 months and recently noticed that beside dizziness in the morning when i get up, i have really been losing memory....about little things and really big things too, until reminded of them. an example of my problem is: when i wake up in the morning i cannot remember what i watched on tv the night before. and often i can't seem to find the right word when i am speaking. i am on 150 mg and it really has been great for the depression, but this memory thing is really beginning to worry me. also, when i drink it seems to really affect me more. anybody else with these side effects? thanks...

Posted by leslie on November 22, 2007 8:02 AM | Permalink | Reply

William I am sorry you are going through this diffiult time. I think you need someone to talk to rather than just meds. You are grieving, and grief hurts more than anything in the world. No meds can make that easier. Try reading up about the grief process. Time will help. Try to hang in there until you get some time behind you and things will begin to improve.

Posted by Stacey on November 23, 2007 1:19 AM | Permalink | Reply


yes! I totally experienced moods that didn't feel like me. For me the anger was secondary to irrtability. It does go away. And for me it did take longer than I expected. It's frustrating but at least you're not alone.

I would say for anyone who is just starting on wellbutrin to hang in there. I found tons of side effects while getting on it and adjusting. Dizziness, dry mouth, irritability, crying MORE, clenched jaw, poor sleep, more diziness...

Ok, maybe I should just stop. My point is that, for the most part, it's not just you. And the side effects (most of them, the dizziness still gets me) will go away.

Posted by Nicole on November 23, 2007 8:22 AM | Permalink | Reply

I took myself off of it (see 11/17). It's been a week and I am returning to normal. I feel more down now then I did before going on it, but I think with time I will naturally be 100%. I will never treat depression with meds again....

Posted by Andrea Searcy on November 23, 2007 9:30 PM | Permalink | Reply

I've been on WBXL for about 8-9 weeks now and I feel like a new person. When I first started taking it, I was doing a lot of drinking. I did experience some of the side effects that some have described but didn't know if it was the WB or the combination with alcohol. I started drinking heavier off and on for the last year due to depression. It was so bad I ended up in the hospital where I was put on this med. I've read several posts where people have mentioned that it might not be for everyone. That must be the case because it has helped me tremendously! I have more energy and a better outlook on life and have had no desire to drink. I hope those who have had a bad experience and are still in need of something that will help will eventually find something that helps you as much as this has helped me.

Posted by Dee on November 28, 2007 8:27 AM | Permalink | Reply

I switched from Effexor due to restless leg syndrome, it was pure h*ll getting off of it, tapered for 6 weeks. Got put on Wellbutrin XL, now at 300 mg a day. Restless leg syndrome now wonderfully absent.

However, I have been had crying jags and angry outbursts ever since I started Wellbutrin (or quit Effexor). I wondered if it was just me; I see it is not. I'm going to taper off of Wellbutrin now and get off of it.

Posted by Leora on November 30, 2007 12:55 PM | Permalink | Reply

Experiencing severe insomia with Wellbutrin.

If you like being up 24 hrs a day take the drug.

I went back to Paxil I can sleep now.

Posted by Jim Clarke on December 1, 2007 4:32 AM | Permalink | Reply

I have been on 300 mg of Wellbutrin now for about 3 months. I've been feeling better, but I noticed that I seem to be clenching my teeth together like I am under stress, but I'm not. I catch myself doing it and then tell myself to release and relax. Then it starts all over again. I don't realize that I'm doing it. Is this this a side effect of Wellbutrin? If so, how long will it last?

Posted by Chris on December 1, 2007 2:32 PM | Permalink | Reply

Week 2, have increased from 150 mg of WB XL to 300. I am less anxious but slightly jittery. I have more hunger pangs, but when i think of actually eating food I'm completely disinterested. When I do eat, I can get down about half of my meal. Am experiencing insomnia again since the increase. I was prescribed 2 mg of lunesa but it is ineffective so far. Oh and the itchiness has subsided.

Posted by edem-enang78 on December 5, 2007 1:00 AM | Permalink | Reply

I've been on the generic (300mgs) now for a week--went straight on it. Noticed some insomnia, but have been dealing with that fine. However today I noticed that my hands are shaking just a bit---so of course I'm thinking I've got Parkinsons--but then thought about starting the Wellbutrin. Has anyone else had this particular side effect? I've heard that tremors could happen--is that what's happening to me?? Would appreciate anyone else who's had this and been fine. oh--also taking Effexor--150mgs, and have been on that for about 5 years. Seemed not to be helping as much, but doctor said I could take both with no problem. Is he right??

Posted by Whitney on December 5, 2007 5:00 PM | Permalink | Reply

i have been taking the generic 150's for around 6 months and ive noticed my mood is better, but as soon as it wears off i feel worse then ever, ive also noticed a higher level of anxiety and i feel overly emotionaly sensative to just about every thing now wich is a huge down side, any one else dealing with the sensativity thing?

Posted by P on December 7, 2007 11:18 AM | Permalink | Reply

I am so addicted to smoking and I really want to quit, but the withdrawals are so awful that I'm considering going back on Wellbutrin like I did 7 years ago. When I took this drug the first time, I felt stoned all the time, which made my job as a waitress interesting to say the least. I did quit smoking, as the cravings just seemed to go away and the cigarettes didn't make me feel any better. It was like the dopamine receptors are blocked by this drug and lighting up just doesn't activate the dopamine reward system anymore.
I don't remember having any problems upon quitting after 6 months, but these posts are scary!!
I know that I have bad reactions to SSRIs and after having what I swear was a Seratonin Syndrome episode with Zoloft, I started having panic attacks which I'm still dealing with every once in a while 2 years later!!
Addicts are stuck in a dopamine reward cycle, and the only way to remedy this is to exercise. (At least this is what I read recently) Addicts have less dopamine receptor sites, and exercise builds new ones. The Welbutrin sits on the dopamine receptor sites and constantly stimulates them, which is what made me so "doped out" when I was on it to quit smoking.
SSRIs do something altogether different. They increase your seratonin, and when you're naturally low in seratonin, your body will have more receptor sites for it (makes sense, more catchers mits up ready to catch the very few balls flying their way) So when I took Zoloft, my seratonin production went through the roof, and all of my numerous receptors were overloaded. That caused the reaction, and I believe it also caused my brain to get all out of whack, which caused the panic attacks that started shortly after the incident. Incidentally I flushed the remaining Zoloft down the toilet that day and have never looked back. I recently tried Prozac for my anxiety because I was getting really tired of dealing with it, and I had awful side effects, to the point of quitting after only 3 days. I say, listen to your body!! Anyways, I guess what I'm on here for is to offer my support to anyone dealing with panic attacks, they're AWFUL and scary, and I think they do definitely get exacerbated by all of these drugs. I'm not Tom Cruise or anything, trust me, I carry Xanax like a freaking security blanket and take half of one from time to time, but I really think that depression and anxiety are sometimes made worse by these drugs that doctors get paid by drug companies to push.
Our bodies and minds have not evolved at the same rate as our lifestyles. We literally have the same brains and bodies that our caveman ancestors had, and with our extremely stressful lifestyles, we are simply not "built" to deal!
Stress relief is key. I'm trying exercise, but as a smoker, that's kind of tough!
Hang in there everyone, you are not alone!

Posted by Jessica on December 7, 2007 5:55 PM | Permalink | Reply

Hi there,

I'm so glad you have this forum! I have been on 300 mg of Wellbutrin for about 2 months. The first few weeks were fantastic. I had tons of energy, the hopelessness disappeared- i was more focussed than i had ever been. I felt like the real me. The past month, however, has not been so great. I have a constant headache on the right side and blurred vision. I have a very hard time focusing. I just feel fuzzy all the time. How do I get back to that feeling I had the first few weeks? Thank you so much for your help!

Posted by Kim on December 8, 2007 8:49 PM | Permalink | Reply

I'm a 48 year old white male who started 150 mg Wellbutrin (WB) XL once-a-day, exactly 3 weeks ago. I stopped today, cold turkey, due to the intense insomnia, anxiety, and agitation it created (and I lost 5 lbs when I didn't want to). Words can't describe how much better I felt today, so much more relaxed. I'm hoping like heck I have a good night's sleep for the first time since I started taking it (my average time falling asleep was around 4-5 am, including some intensely uptight all-nighters). I've had mild depression about 1/4 to 1/3 of the time, for almost 20 years now, but dealing with that was nowhere near as debilitating as the above-mentioned side effects.

And I need to add that the WB greatly exacerbated my restless leg syndrome (RLS), another serious factor contributing to my insomnia. Interestingly, WB is supposedly a help for many experiencing RLS. For me, it had the opposite effect.

Reading many of the informative posts here clearly illustrates how the same medication may be one person's trash and another person's treasure. Hopefully we'll all find that pot-of-gold at the end of our painbow.

Not certain I'm going to pursue other alternatives.

Posted by Bucky on December 9, 2007 4:12 AM | Permalink | Reply

Well I am trying it again. I just have one question. After taking WB for about 4 years. At 450 mg XL it all of a sudden stopped working. I went for a good 6 months begining to expierence symptons of the past. Fatigue, sleeping all the time, "weight re-gain", very low self esteem. So I quit taking it. At 450 mg there are a lot of side affects that just were not worth going through if the meds weren't going to work anymore. Howerver, now a year later I have gained 75 lbs, no motivation to do anything, sleep all the time and my body just won't co-operate to do anything I need to do in life. So I'm going back on it. Has ANYONE EXPIERENCED THIS MED JUST STOPPING, NOT WORKING ANYMORE????? please share if you have...

Posted by Deb on December 9, 2007 4:58 AM | Permalink | Reply

I started the generic WB, 150 mg, 2x a day, a week ago. I have energy once again to do things. I am more focused, don't think about stuffing my face all the time, and of all the ones I've tried, I like this one the best (so far). Paxil gave me terrible withdrawls, Serzone, Prozac, and Lexapro made me terribly tired. It hasn't seem to kick in for the depression yet, but I'm moving from Lexapro to WB, so it may be that the Lexapro is leaving my system, and the WB hasn't built up yet. I'll keep you posted!

Posted by Tammy on December 10, 2007 11:28 AM | Permalink | Reply


I have been taking Wellbutrin XL for almost 3 weeks now. I had a little dizziness and shaky hands at first. I have noticed an increase in energy and am overall feeling better. These last few days however I have had frequent urination...I am constantly going to the bathroom. I did see this as a possible side effect on their website? Just wondering if anyone had this and if it got better. I am assuming it will but just takes time. I have not experienced any weight gain which is great...Paxil made me gain a ton of weight right away.
Thanks for any input.

Posted by Amanda on December 11, 2007 7:09 PM | Permalink | Reply

I started taking wellbutrin about 3 weeks ago now. The past two days have been absolute hell at night time. I am on a very low dosage (100mg 2x day). I take the first pill at 6am when I wake up and the second at 3pm because of sleep problems. The past few nights (around 8 or 9pm) I have been experiencing AWFUL mood swings. I went through a family tragedy back in April (main reason for the med) and with the holidays approaching I don't know whats the cause of what at this point. Has anyone else experienced mood swings that after the fact they look back at the situation and feel crazy?! If so, did you continue taking the med--and if you did, did things smooth out quickly? There are a lot of factors that play into it--grief, depression, etc so it's hard to say what might be the cause of what, but I never had mood swings like this before taking Wellbutrin. Any advice would be great. Thanks.

Posted by Kara on December 12, 2007 6:45 AM | Permalink | Reply

The info in this forum has helped me beyond measure. I've been on WB for a couple of months, and it's been a nightmare. My meds nurse increased my dosage from 75 mg two times a day to 150 mg two times a day about 2 1/2 weeks ago. I've had horrible, devastating mood swings, bad enough that I contemplated checking myself into a mental hospital last night. Reading the posts here made me feel so much better, I can't begin to tell you how much! After talking to my meds nurse, the dosage has been lowered to its original level. At least until I can see her. I was on Prozac prior to the WB and want to go back to it. Hopefully this will not be difficult, but I will fight for it if I have to. Again, thanks for all the posts! They really helped me a lot!

Posted by Kate M on December 13, 2007 10:48 AM | Permalink | Reply

I've only been taking Wellbutrin XL for two days and I've developed this weird pain in my lower back and liver area. Do you think it could be the meds?

Posted by Jenny on December 13, 2007 11:33 AM | Permalink | Reply

Week 3. I've switched to generic WBXL because of my insurance. It has been 3 days since the switch and I haven't noticed any adverse side effects as some people posted here. I eat WAY less than I used to. SO, far I've lost a total of 5 pounds in 3 weeks. It's not that I am starving myself, I just am completely apathetic when it comes to eating if that makes any sense. When I do eat, I eat until I'm satisfied. I used to eat until I felt stuffed. I continue to have more energy and am functional. I've been out of work, save temp assignments here and there, for about 6 months and would stay in bed all day before the meds. I think part of why I haven't been hired is the depression, I looked awful before. I was just miserable and it showed. I'm less anxious and shy when meeting new people. Most importantly, I don't feel so hopeless. I have experienced a couple of crying jags which are kind of embarassing. Also my neck is so stiff. I've been walking around smelling like Icy hot the last couple of days.

Posted by edem-enang78 on December 14, 2007 12:19 AM | Permalink | Reply

For Kim: posted 12/8/07

I too have experienced a miraculous boost in energy and have only been medicated a few weeks. My psychiatrist explained that its the initial abundance of serotonin (sp?) in my brain and that I may have some more down periods as I level out on the meds. Give it a little while longer and you'll probably feel better. You are still in a period of adjustment.

Posted by edem-enang78 on December 14, 2007 12:28 AM | Permalink | Reply

I have been on WBxl300 with food and without for about two weeks and early this week I started to experience flu like symptoms. Nausea, vomiting, diarea, and constant stomach pain. Does anyone know if this goes away? I feel like I can't function because I am sick. I would really appreciate some advice on this. Thanks

Posted by Rhonda on December 14, 2007 10:10 PM | Permalink | Reply

My doctor paired up Wellbutrin and Lamictal together. Has anyone else had that recommendation come their way? Any concerns I should have? Does anyone know if if either can impact Libido and/or testosterone production?

Posted by Curious on December 16, 2007 2:04 PM | Permalink | Reply


Crazymeds' domain registrar messed up, and they lost the website name. It's back up at crazymedz.org .

Posted by ith on December 19, 2007 5:16 PM | Permalink | Reply

Liane! Don't jump back on the brain chemistry altering drug train again before you try some SERIOUS mineral loading for a couple weeks. Heck, give it a month and see what happens. I know it seems hopeless sometimes, but I've dealt with anxiety and panic attacks for years, and this seems to help me way more than any drug ever has.
Before you go to bed, take:
500mg Calcium Citrate; 1,000 mg Omega-3 (wild salmon); 250mg Magnesium; and a Blood Builder tablet (by Mega Food).
I've gone back and forth for years as to whether or not this natural approach is worth a darn, but the side effects of the drugs are so awful for me that I am willing to try it again. I've been doing this for a while and feel good. Also, with anxiety, you might just have to quit running and face up to why you are experiencing the anxiety in the first place. Search and search until you find the right person, and talk!! A psychotherapist can do wonders, my panic attacks have been greatly diminished since I figured out my issues and told a few people in my life how I feel.

Posted by Jessica on December 19, 2007 9:44 PM | Permalink | Reply


I just started wellbutrin about 9 days ago. Well the side effects have really kicked in the last 3 or 4 days.

Extremely gassy, bowel movements 3 or 4 times a day, it has totally aggravated my acid reflux, as well as a tingling sensation in my head.

Has anyone else had these side effects, how long did they last? It's driving me crazy thinking its my heart or something else bad.

Posted by Tom on December 21, 2007 7:07 AM | Permalink | Reply

I have been on WBXL for a few years now. Also I have just taken up drinking. Last night i had a bad night. I usually take my pill in the morning but yesterday I forgot to take it until the night. I also went out that night and drank. Then today i couldn't eat at all and got sick a few times. I have been able to go out if i take my pill in the morning and not wake up feeling like i was in a fight the night before. I just wanna know if that happens because i took my pill that night or if i drank too much. and i knwo it says it on the bottle but this hasn't really before.

Posted by will on December 21, 2007 11:21 PM | Permalink | Reply

I know this is not cool to post a questions without reading all the other posts cus the answer may be out there, but because of what I think might be side effects of the wellbutrin, I'm having trouble reading and concentrating. My situation is complicated by the fact that I don't know if I'm experiencing paxil withdrawal or wellbutrin side effects. Does anyone else on Wellbutrin experience a "ch ch" like sound/ sensation, especially when looking a different way, or feel dizzy, lightheaded, kinda disoriented, nauseated... Anyone elses thoughts about whether this is paxil w/d or wellbutrin s/e would be so helpful!

Posted by Virginia on December 22, 2007 2:33 PM | Permalink | Reply

I was started on 150 xl then went to 300 about 3 wks ago. Have been taking it at night. I've been losing sleep then developed bad headache the past 2 days. last night I had such a bad nightmare followed by severe panic that has lasted all day off & on Now I'm sorry I took the dose again tonight I don't want to even take it tomorrow even in the day all I ask is to make it thru the night w/o feeling so scared if anyone is there please talk to me

Posted by diane on December 22, 2007 8:12 PM | Permalink | Reply

this is for tom ya I've also experienced the 3-4 bowel movements daily. have not minded cuz things r usually the other way for me

Posted by Diane on December 22, 2007 8:33 PM | Permalink | Reply

I was taking various anti-depressants for many years, and none of them seemed to help. I changed to a different Doctor and was diagnosed with bi-polar disorder. I was put on Wellbutrin XL 150 and Topomax. I take the Wellbutrin in the morning and the Topomax at night. I sometimes still have episodes of depression, but it is usually pre-menstrual related. I take prozac during those extra bad days.

Posted by michele on December 23, 2007 10:00 AM | Permalink | Reply

Hi, I just got off of Effexor 37.5mg and started Wellbrutin XL 150mg. I feel worse than ever I am walking around hating everyone X-mas with my kids I'm so sad. I hate my husband he just gave me clothes and I want to divorce him because he dosen't spend anytime or interest in me. I'm fighting and crying all the time. I don't know if I should stick it out. Effexor was great but really effected my libeato. Pls help. Lori

Posted by lori on December 25, 2007 8:11 AM | Permalink | Reply

I started taking Wellbrutin XL 150mg a couple of weeks ago to counteract my case of 'holiday blues'. It's worked fine for elevating my mood and decreasing the frequency of crying spells, however the drug has given me an awful case of cotton-mouth. My mouth is so dry I have to drink water constantly which of course, makes me go to the bathroom quite a bit. Does this annoying side effect subside with time? Thanks & Happy New Year.

Posted by Skip on December 27, 2007 10:02 PM | Permalink | Reply

I have been on the generic form of Wellbutrin XL for about 8 weeks now. I have always been one to have migraines but they seem to have gotten worse over the last few months. My most annoying side effect is the dry mouth! The nurse at my work said to be careful because severe dry mouth could lead to other mouth problems such as thrush. I have now began obsessing about this which is making it even worse! I know that it is a side effect but how bad will it get?? Any thoughts would be great!

Posted by Stacy on December 28, 2007 11:36 AM | Permalink | Reply

this is a comment back to virginia. I was on both lexapro and wellbutrin at the same time and I didn't think I needed to be on both so I quit the lexapro and now I'm on 150mg of Wellbutrin XL. I have only been taking the wellbutrin without the lexapro for about 7 days now. I have had the same symptoms so bad to the point where I was going to go to a neurologist to get my head checked. I have a very funny feeling in my head when I move it side to side or when I get up from lying down. It feels as if I'm going to pass out. I also for the past 2 days have had a problem with tingling/numbness sensations in both of my hands. I work EMS and I keep a check on everything when I feel like this, so I'm thinking that it is the medication. The bad thing for you and me is I don't know how long this lasts. If it last too much longer I'm going to be one of those that does the cold turkey way and hope that the side effects of that is not worse than they are now. If anyone knows the answer please let me know.

Posted by timberly on December 29, 2007 6:04 PM | Permalink | Reply

After freaking out about the dry mouth, I quit cold turkey on Saturday. Today (Monday) I went to the Dr to discuss the dry mouth issue and what the nurse at work told me about thrush. She assured me that the dry mouth is the most common side effect of Wellbutrin and that there is virtually no way that dry mouth alone will cause thrush. She did, however, tell me that the dry mouth will probably not subside as long as I am taking Wellbutrin. Now I have to decide if the dry mouth is worth it...I think it is. I have lost 13 pounds in the last 8 weeks. I have already noticed after not taking it for 3 days that I am eating like a pig again! So I guess I will go back on it...

Posted by Stacy on December 31, 2007 3:17 PM | Permalink | Reply

This is a response to posting 325; Virginia on December 22. I too have been on Paxil for several years and I am in the process of transitioning to Wellbutrin. I am experiencing the same side effects as you described in your posting. I'm thinking it may be a combination of effects caused by weaning off Paxil and starting Wellbutrin. I have gone without Paxil for several days in the past because I was low on pills and didn't get them filled. During those times I felt strange sensations when I bent over to pick something up or when I turned my head. Hard to dscribe the sensation but it was strange and I had an associated strange feeling in my tongue as well.

Posted by Felix on January 1, 2008 11:17 AM | Permalink | Reply

I've now been on Wellbutrin for 1 month. The dry mouth has subsided, and overall I feel pretty good. I have vivid dreams, not as hungry and I don't focus on coffee and chocolate like I used to. I sometimes feel edgy or weepy, but overall, I feel pretty good with alot more energy than ANY of the others I've been on.

Posted by Tammy on January 2, 2008 10:57 AM | Permalink | Reply

Has anyone had problems with a change in mood while on Wellbutrin? Like erratic or aggitated behavior? Thanks!

Posted by Cindy on January 3, 2008 11:52 AM | Permalink | Reply

I just wanted to say that I changed from Lexapro (for anxiety ) to welbutrin 150 twice a day about 5 months ago because i thought the lexapro was making me gain weight. Boy do I wish I had never done anything. I have become irritated by the slightest thing and I can cry if somebody looks at me wrong. I didnt realize this was a side effect until recently and I do not like the way I have started to be mean to my family and boyfriend. I am going back to lexapro pronto.

Posted by pammy on January 3, 2008 4:19 PM | Permalink | Reply

I just wanted to say that I changed from Lexapro (for anxiety ) to welbutrin 150 twice a day about 5 months ago because i thought the lexapro was making me gain weight. Boy do I wish I had never done anything. I have become irritated by the slightest thing and I can cry if somebody looks at me wrong. I didnt realize this was a side effect until recently and I do not like the way I have started to be mean to my family and boyfriend. I am going back to lexapro pronto.

Posted by pammy on January 3, 2008 4:19 PM | Permalink | Reply

I have been on wellbutrin 150 mg XL once a day for 3 weeks now... The 1st day, I felt thus burst of energy, but it went away pretty quickly. The last 2 weeks, I have felt increasingly irritated and angry.. I feel this urge of throwing things when something does not go my way, which never happened before.. My family is suffering from the present situation and I don't know whether I can hope that these effects will vanish any time soon. I also keep having these suicidal thoughts...
I tried Prozac before but had to stop because of the anxiety it was causing..

Posted by Pierre on January 4, 2008 8:21 AM | Permalink | Reply

I just started taking Wellbutrin XL 150 and have had the worst dreams and hallucinations at night I have ever experienced. I have woke up out of breath and extremely scared from some of my dreams. Has anyone ever experiened weird or scary or too real feeling dreams??

Posted by Heather on January 4, 2008 10:20 AM | Permalink | Reply

I have been taking Wellbutrin XL 150 mgl for 3 weeks now and had a very bad dream last week. I dreamed that I was taking sleeping pills from my bathroom cabinet, then went to the cellar to pick up a couple of bottle of wine. I then left home to check in a motel and started drinking a mixture of both.. At that point in my dream, I woke up in disarray..

Posted by Pierre on January 4, 2008 10:31 AM | Permalink | Reply

I've been on WBXL 300mg for a year and a half now. I've never had any side effects until the past couple of weeks. I've had a few episodes where this wave comes over me and my heart starts beating very fast. I don't know what a heart attack is like, but it feels like my heart will beat out of my chest. I've also been very drowsy and yawning all of the time. I'm concerned because I think it's odd that I've never had side effects (not even weight loss)before and now a year and a half into it, I am. Has this happened to anyone on here? I've noticed that most of you are having side effects within a few months of starting WB.

Posted by Jennifer on January 5, 2008 11:37 AM | Permalink | Reply

I forgot to mention that I started taking a low dose of oral contraceptives (Apri) 3 months ago too. I haven't read anything about these conflicting with WB though.

Posted by Jennifer on January 5, 2008 11:49 AM | Permalink | Reply

I was prescribed Prozac 40 mg and Wellbutrin SR 300. My doctor didn't tell me to start off just taking the 150 mg for a few days! So, perhaps because of that, I had some pretty scary side effects. The worse one was how my head felt. I can't even find words to describe it, but there was a very heavy, dizzy, and busy feel to it. Also my neck got really hot and I was jittery. Insomnia (which I had before anyway, but it made it worse). The worst days were 2-4, at one point I thought I was going to die my head felt so strange. By day 5 (today) I feel pretty normal, and my head is clear now. I did have constipation, just today. No dry mouth or excessive thirst as some seem to have. PS I am on the generic buproprion.

Posted by Wannabee on January 6, 2008 1:34 PM | Permalink | Reply

has anyone noticed undigested wellbutrin sr 150mg in their feces? I guess i should say i take 150 mg 3 times per day. i've taken this dose off and on for several years and have never had this problem. it worries me, plus i know things are not right. i am very emotional and want to sleep my life away. without it, i am a total *#%@ if you know what i mean. please offer any advise. thanks!

Posted by shonda on January 6, 2008 5:24 PM | Permalink | Reply

I still experience crying jags.

Posted by edem-enang78 on January 8, 2008 2:55 PM | Permalink | Reply

Wow.....good to know that I am not the only one with some of these symptoms....of late I see the anxiety and near panic following the first hour after my one a day dose of 150mg SR. It seems to subside after an hour or two, but in general I feel hyped up most of the time. I am able to focus much better at work, and don't seem to have the down moods I used to have. The flip side is that I feel nervous a good deal of the time, and OCD symptoms are increased. Wife also says that I am much more aggressive and even paranoid at times....I can see a bit of this but hard to be very objective about yourself of course. I am considering asking to be taken back to the 75 mg once a day dose to see how that works. Good luck to all of you with your challenges. It seems like a good drug, but needs to be monitored for the variations in body chemistry between people.

Posted by Bill on January 8, 2008 8:11 PM | Permalink | Reply

I am bipolar 1 and was put on Wellbutrin XL 300mg before I was diagnosed. It cured my depression but threw me into mania, I didn't sleep for 2 weeks! I wouldn't recommend it if you are bipolar.

Posted by CLM on January 9, 2008 8:44 AM | Permalink | Reply

Wow...I'm surprised to see so many negative side effects! I've been taking 300mg for 4 years now (afraid to go off just because of "life" before the drug!) with not a single problem. I was on Zoloft for a year before and gained 30 lbs. Three weeks after beginning the welbutrin, 16 lbs had melted away, and the emotional numbness from the Zoloft was also thawing. Wellbutrin makes me feel "normal", and even a so-called psychologically normal person has his or her minor ups and downs.

Posted by jodi on January 10, 2008 6:05 PM | Permalink | Reply

54 year old female, heathy and active/fit, on WB for 18 months for depression. Happy w/ results. Long term side effects have been tingling in extremities when I wake up at night. Some of the RLS sensations others have mentioned. Insomnia less than that associated with menopause, thankfully. Feeling "dizzy" around midday most days is a recent development; have not felt as if I would lose balance until today. Got to a chair. Most disconcerting, but single event so far. Anyone have this effect? Anyone ever actually lose balance? Scary to think about this occurring while driving. Some weepiness lately...does one develop a tolerance for the drug long term?

Posted by L on January 18, 2008 8:27 AM | Permalink | Reply

Has anyone had the side effect of a bad taste in your mouth. When I first started on WB, a couple of years ago, I was taking too high of a dose and it was causing a bad taste in my mouth. I read at the time that this was a possible side effect but I do not see this side effect listed anywhere now. I am again experiencing this bad taste and am wondering if it is the WB. Any comments?

Posted by Suzy on January 20, 2008 4:48 PM | Permalink | Reply

At 37.5mg I felt great but it affected my libido. I was put on Wellbutrin XL 150 mg. and that was ok but didn't "carry" me as well so it was upped to 300 mg. The side effects were terrible, and I was heading into a bad depression, so back to 150 mg plus the Dr. added Cymbalta 30 mg every other day. So far so good. I still have a sllight dry mouth frequently, and lots of gas, but no diarrhea. I take Phazyme to reduce the gas, and that helps a lot. I do have a few strange dreams but not bad.

Posted by Maddy on January 31, 2008 1:41 PM | Permalink | Reply

Has anyone experienced increased gastritis/upper abdominal pain with WBXL? I had been on Prilosec for gastritis prior to starting on it with good relief from my GI symptoms and now find that I'm having increased discomfort. Anyone else?

Posted by Patty on February 5, 2008 3:20 PM | Permalink | Reply

I'm experiencing gastritis too... it's awful and really painful :(

Posted by Sandra on April 24, 2012 8:11 AM | Permalink | Reply

I do wonder if Wellbutrin has lead to a worsening of my reflux....could be

Posted by Gregory Gauthier on February 7, 2008 6:38 AM | Permalink | Reply

Have been taking Wellbutrin (along with weaning off lexapro) for 2 weeks and am experiencing pretty bad headaches and blurred vision.
Also waking up very tired but am starting, after the 1st week, to sleep through the night.
Does anyone else experioence the headaches from the wellbutrin or perhaps it is the reduction of the lexapro.
Thanks, Paul

Posted by Paul on February 7, 2008 7:59 AM | Permalink | Reply

Have been taking Wellbutrin (along with weaning off lexapro) for 2 weeks and am experiencing pretty bad headaches and blurred vision.
Also waking up very tired but am starting, after the 1st week, to sleep through the night.
Does anyone else experioence the headaches from the wellbutrin or perhaps it is the reduction of the lexapro.
Thanks, Paul

Posted by Paul on February 7, 2008 8:00 AM | Permalink | Reply

I am on my 4th day of the generic wellbutrin... Today I noticed I was yawning all the time, and the anxiety is starting to lift...Something happenend today that would trigger my anxiety.. i would generally not be able to work, want to leave, or start crying.. I would feel so out of control.. Today (day 4) was different.. I still feel the anxiety but I can function...It's weird but good... Like I said, only Day 4.. i'll check back.. btw.. i'm on 150mg a day..

Posted by Sheila on February 8, 2008 11:51 AM | Permalink | Reply

I started taking wellbutrin sr instead of the generic that I had been on for 5 years and have had a horrible experience.
I have very bad anxiety, rash, face flushing, irritability, racing thoughts, manic behaivor, even more severe depression, and body aches. I have been in pain since taking this, and I was starting with only 75mg.
Be very cautious when starting this, and have close friends and family monitor your behavior. I am switching to something else, what I do not know yet, but I would rather have depression than depression with all of these side effects.
The generic may be better for some, it was for me.

Posted by mo on February 10, 2008 3:21 PM | Permalink | Reply

Hi i've been on celexa for 3 years for anxiety and i finally winged off it which the withdrawls were really harsh. Now i'm on wellbutrin XL I like how i feel mentally right away i felt like my old self again all happy, but my stomach has been torn up. It's been three weeks and everytime i eat i get sick and either end up puking or having extremely bad stomach cramps and diarea. It is so bad and hard to live with, specially working haha. I'm trying my best to hang in there and i self pay my doctor so I don't want to go back to just be told hang in there. Is this the best wellbutrin or is thier a lower dosage. or can anyone tell me how long the stomach issues go on for??? I feel perfect till i eat and it doesnt take long before the cramps come on ( like labor pains sometimes that strong), and i have to run to the bathroom. Someone please help me understand what i need to do and if its worth hanging in there. thanks jess

Posted by Jessica on February 16, 2008 9:54 PM | Permalink | Reply

Hello, I've been on 300mg of Wellbutrin XL for about 4 months. My dark depression has faded. I lost 15 pounds, and has helped with my IBS. My dreams have been increasingly intense, very vivid and realistic, which scares me a bit. I'm a smoker and i have quit until i drink alcohol. Which I'm not sure is such a good idea but have not had any side effects from drinking and taking WB. The side effect that i really dislike is my moodiness increased and i started crying at things i usually would not cry about. I also say things that i would usually not say. Sometimes it's a good thing because im not embarrassed anymore but when i get upset (which happens very easily now)its all downhill from there. I wanted to know if anyone has had this side effect and if so what they did to fix it. Should i higher my dose to 450mg? I really am concerned and would love someones advice. Thanks

Posted by Bonnie on February 17, 2008 10:36 AM | Permalink | Reply

Hello, I've been on 300mg of Wellbutrin XL for about 4 months. My dark depression has faded. I lost 15 pounds, and has helped with my IBS. My dreams have been increasingly intense, very vivid and realistic, which scares me a bit. I'm a smoker and i have quit until i drink alcohol. Which I'm not sure is such a good idea but have not had any side effects from drinking and taking WB. The side effect that i really dislike is my moodiness increased and i started crying at things i usually would not cry about. I also say things that i would usually not say. Sometimes it's a good thing because im not embarrassed anymore but when i get upset (which happens very easily now)its all downhill from there. I wanted to know if anyone has had this side effect and if so what they did to fix it. Should i higher my dose to 450mg? I really am concerned and would love someones advice. Thanks

Posted by Bonnie on February 17, 2008 10:37 AM | Permalink | Reply

I started WB 2 weeks ago at 150 mg. and have had major emotional outbursts, edginess and irritability along with suicidal thoughts and a decreased threshold for emotions and a spacey feeling. Will these side effects go away?

Posted by Susan on February 18, 2008 3:10 PM | Permalink | Reply

I started WB SR about a week ago, and within a few days I started feeling very intensely anxious for no good reason. Out of nowhere I would be shaking and crying and wanting to hide in bed. I thought this medication took awhile to absorb into your system? Is this a side effect? If so does it go away?

Posted by Penni on February 19, 2008 11:37 PM | Permalink | Reply

I started Wellbutrin a week ago at 150mg and am to increase to 300 (on SR). I'm afraid of increasing for fear of a seizure (I have had anorexia and bulima - not since 7 yrs. ago, but am still concerned, and my eating habits are still bad). The Dr. seems to think I'll be ok though. Any thoughts on the seizures associated with eating disorders??? Also, within the past 3 days I've been feeling VERY shakey inside/like shocks going through my body - not painful, just abnormal and am wondering if anyone else had experienced this. It feels like what I experienced when I missed my Effexor for a day - and the feeling lasts all day. Thanks for any response.

Posted by SCM on February 20, 2008 3:28 PM | Permalink | Reply

ive been on welbutrin for 4 weeks now and noticed that all ive gotton from it was feeling like a zombie and nervousness all the time. i have A.D.D and i think that once your on welbutrin all of your creativity goes away so i want to get off this stupid drug but im worried about the withdrwal sypotoms... can anyone tell me if going off it will have serious side effects

Posted by Bobby on February 21, 2008 4:45 PM | Permalink | Reply

I have been on WXL for 2 1/2 months. My weight loss has slowed down. I'm losing between 1 and 2 pounds every 2 weeks. Total weight loss so far is 27 pounds. I am genuinely happy. It is hard to believe that I was suicidal just 3 months ago. This is not to say that I didn't experience any side effects because I did. I had severe headaches and the feeling that my head was too heavy for my neck. And the insomnia. I was prescribed lunessa for that and that helped alot. I'd have stomach upset and constipation as well. For the most part all of the side effects have subsided. My appetite has returned, though I still don't eat as much as I did before. I'm less compulsive. I'm not so quick to anger. My friends have all commented on the changes in me. I just feel better. I'd be content to be on tis medication for the rest of my life........

Posted by edem-enang78 on February 23, 2008 12:33 PM | Permalink | Reply

I have been on Wellbutrin for about 4wks and Cymbalta for about 6wks. I have noticed my urine smells bad. Could this be from one of these meds?

Posted by Michele on February 23, 2008 2:06 PM | Permalink | Reply

I have been on Wellbutrin for almost 3 months now to prevent anxiety attacks and increase my libido hopefully. I was having panic attacks with no warning so things like Ativan didn't work. A month ago, when I developed extreme sadness (lots of family stress) I went back. She didn't want to increase the 150 mg so just added 12.5 mg time released Paxil. Within 3 weeks I became my normal cheerful self, much to my husband's delight. I have not had a panic attack in 3 months. My side effects seem limited to hand tremors and yes, my urine has developed an unusual odour.
I am very happy with my mixture and feel quite normal already, just keeping a Tide pen handy for the spilled coffee.

Posted by Kimberley on February 23, 2008 6:46 PM | Permalink | Reply

For Post 388 that Ashley wrote. Sorry to hear that generic didn't work for you. I started the first two weeks on WXL and then had to switch to generic for insurance purposes, but I didn't notice any adverse effects.

Posted by edem-enang78 on February 26, 2008 12:55 PM | Permalink | Reply

I'm a 44yo male and have been on 450 mg of Wellbutrin XL for about 18 months. This is the first med that I've tolerated... doc tried me on several. My lasting side effects are an occasional slight dizziness and crying. The crying can be a problem. Damn, I've cried at commercials! I should mention that I'm not what you'd the picture as the crying type - 6'2", 275lbs a former college football player and now owner of a construction company. Needless to say, this has caused some awkward situations...

Posted by Scott on February 27, 2008 4:35 PM | Permalink | Reply

3 months total on generic Wellbutrin now. Dosage taken from 100 up to 150 3 weeks ago. Last weekend hand, arm and leg tremors hit peak, but seem to have subsided this week.

Posted by Kimberley on February 28, 2008 5:22 PM | Permalink | Reply

I am so glad I found this site. I have been to the doctor twice this week and to the ER once. I started SR 150mg two weeks ago. Paranoia, hot and itchy hands and feet, electrical shocks, and extreme anxiety have been a real problem. Has anyone else experienced this?

Posted by Saya on February 29, 2008 2:08 PM | Permalink | Reply

I've been on Bupropian SR for 3 months now and of all the antidepressants I've tried, this one is the one that I can tolerate. I do have vivid dreams, but most of the side effects have diminished. The only one that hasn't that does frustrate me is short term memory lost. I can't remember a darn thing anymore!

Posted by Tammy on March 4, 2008 12:57 PM | Permalink | Reply

Anyone else have the ear ringing? I'm on 450 mg welbutrin daily since dec. ears started rining on 300mg in october. worse with the increase. At first I didn't mind it - almost felt comforting - in an odd way. but now it is very loud. I'd like to up my dose, but am very hesitant because if the rining gets louder i'm afraid i won't be able to think.... anyone else have this?

Posted by e on March 4, 2008 8:29 PM | Permalink | Reply

Anyone else have the ear ringing? I'm on 450 mg welbutrin daily since dec. ears started rining on 300mg in october. worse with the increase. At first I didn't mind it - almost felt comforting - in an odd way. but now it is very loud. I'd like to up my dose, but am very hesitant because if the rining gets louder i'm afraid i won't be able to think.... anyone else have this?

Posted by e on March 4, 2008 8:29 PM | Permalink | Reply

my doc thinks I should try wellbutrin..I am afraid to medicate but I cannot seem to feel better on my own..I am a stay at home mom and somedays I feel like just leaving..or not getting out of bed and just laying there and crying all day.I am really bitchy to everyone and often have alot of anger.my patience is gone..and I have to operate on automatic to function enough to make sure the kids are well taken care of...clean,fed, comfortable etc...I try to make everything happy for but I have no energy or desire to play with them anymore..they miss the old mommy who laughed alot intstead of crying all the time..any advice on wellbutrin anyone?I have never medicated for depression before..

Posted by elaine on March 5, 2008 7:46 AM | Permalink | Reply

my doc thinks I should try wellbutrin..I am afraid to medicate but I cannot seem to feel better on my own..I am a stay at home mom and somedays I feel like just leaving..or not getting out of bed and just laying there and crying all day.I am really bitchy to everyone and often have alot of anger.my patience is gone..and I have to operate on automatic to function enough to make sure the kids are well taken care of...clean,fed, comfortable etc...I try to make everything happy for but I have no energy or desire to play with them anymore..they miss the old mommy who laughed alot intstead of crying all the time..any advice on wellbutrin anyone?I have never medicated for depression before..

Posted by elaine on March 5, 2008 7:46 AM | Permalink | Reply

E - I had ringing in my ears at first...was worse when I drank alot of caffeine. I don't have it at all now.

Posted by Tammy on March 5, 2008 7:47 AM | Permalink | Reply

I'm in the process of weaning myself from Effexor while I start the Wellbutrin. Last week I stepped down off the Effexor in the manner that my doc prescribed, but things were a bit wonky in my physical chemistry. I took a miss on the last dose of Effexor and instead increased the Wellbutrin to the 300 mg I was going to increase to anyway-- essentially I cut four or five days out of the prescribed transition calendar.

The reason I did this is because the dizziness has really become obstructive in terms of my ability to get out of bed and proceed with normal activities. A couple of years ago I was on Lexapro and recall that I experienced the same side effect, though to a lesser degree, while ramping up the dosage. It was hell, is hell, but in the case of Lexapro was worth enduring because it helped my mindset so tremendously.

Anyway, sorry to blather on-- after reading through most of the posts on here I noticed that only a handful of people have experienced this dizziness (on top of the tearfulness, which I attribute to being off a tear-stifling sugstance), most recently Scott. Does the dizziness wane over time? Or does it just remain with you? And, in general, how long does it take for initial side effects to decrease to the level where they will remain? Anyone?



Posted by E.L. on March 6, 2008 8:18 AM | Permalink | Reply

No weight gain here, only a loss. I started out at 212 and am down to 204 after 2 months. Good side effect for me.

Posted by Tammy on March 11, 2008 12:46 PM | Permalink | Reply

I have been taking Wellbutrin SR for 4 weeks now. The first 2 weeks was 100mg SR, and the past two weeks has been 200 mg SR (100 mg twice a day). I feel like I can concentrate better on day to day things, like busy work, and talking to people, but my "big picture" thinking is very cloudy. Basically my life on wellbutrin feels like a regimented process of getting through each day. I don't think about my future anymore. I don't really have hopes anymore. I can't make decisions about things that aren't happening right this second (for instance I had the hardest time committing to a weekend trip for tomorrow). I really don't like it. I don't feel like myself. Before I went on wellbutrin I had confidence and self-esteem issues, now, I just flat out don't care about anything really. And that scares me. I want to quit taking it and do counseling with a psychologist. I'm really scared that I will never get back to the mindset that I had before wellbutrin. I wish there was something I could do to "reset" my brain back to where it was.

Posted by Mark B. on March 13, 2008 1:58 PM | Permalink | Reply

Hi i've been on WB XL for about 3 months now i went through all the side effects of stomach problems, sick, headaches,etc. Now those are gone and it should be in my system but i'm way bitchier on this stuff. My husband walks past me the wrong way and i flip out over nothing. I have no patience at all for anything. I haven't lost weight and i still feel depressed more than before. is this just a side effect before it starts working good or is 3 months to long and this wb xl just isn't going to work for me? please help me

Posted by Jess on March 13, 2008 4:10 PM | Permalink | Reply

Hi, I got the generic 150SR in the mail a few weeks ago, and it made me feel like a total zombie. By day 4, I thought my head would explode and I thought, 'this can't be right.' So I threw it in the trash and called back and asked for the brand wellbutrin, and started it today. It is completely different from the generic so far. Well, this is day one. I'll keep you posted.

Posted by mari on March 13, 2008 5:35 PM | Permalink | Reply

int he begining of WB XL I felt like eating less and felt great mentally now almost 3 months into it i'm feeling a huge appitite again and depression? what is going on? I haven't missed on pill why is it reversing on me? will i get to where i feel better again?

Posted by jess on March 13, 2008 7:12 PM | Permalink | Reply

Have been on Welbutrin SR for 11 days now (100 mg) and am having increasing problems with insomnia. I am a moderate drinker (1-3 glasses of wine a day). Is this the problem? I feel very upbeat and sociable and my anxiety and irritability has greatly reduced, but I can't sleep . Am ready to give this up and settle for some depression to avoid sleep deprivation. The instructions say no drinking - should I be giving up altogether on alcohol?

Posted by Mark on March 16, 2008 4:36 AM | Permalink | Reply

You are correct in that you should not be drinking with the Wellbutrin. Also, when are you taking it? I would highly recommend taking it as soon as possible in the morning, it can cause insomia.

Posted by Greg on March 16, 2008 9:23 AM | Permalink | Reply

reply to 353: I have had two occasions recently that I passed a large yellow jelly bean type item in my stools. It floats. I know this is gross, but when I cut it open it had the consistency of a gummy bear, and it had a white cotton like center. Last night after passing another one I did an experiment and put on of my Wellbutrin XR in a glass of water. This morning it swelled up into a white jelly like "bean". Maybe after it passes the outside turns yellow. I have searched the net and found a few other people have this exact thing, but none of them mentioned they were on Wellbutrin. I will follow it up and let you know.

Posted by pamela on March 17, 2008 9:03 AM | Permalink | Reply

Day 5 on the brand 150 sr is going very well, nothing at all like the generic, which I had to stop after day 4 because I felt HORRID.
Greg, my instructions say NOT to stop alcohol when starting wb, please read yours again. But I do agree that morning is the best time for dose.

Posted by Anonymous on March 17, 2008 7:04 PM | Permalink | Reply

Am posting same thing again because I'm new to this thread and didn't mean to post as an anonymouse...won't happen again.
Day 5 on the brand 150 sr is going very well, nothing at all like the generic, which I had to stop after day 4 because I felt HORRID.
Greg, my instructions say NOT to stop alcohol when starting wb, please read yours again. But I do agree that morning is the best time for dose.

Posted by mari on March 17, 2008 7:17 PM | Permalink | Reply

What are the side effects of Budeprion SR if you stop cold turkey .

Posted by peter bach on March 18, 2008 3:06 AM | Permalink | Reply

What are the side effects of Budeprion SR if you stop cold turkey .

Posted by peter bach on March 18, 2008 3:07 AM | Permalink | Reply

What are the side effects of Budeprion SR if you stop cold turkey .

Posted by peter bach on March 18, 2008 3:07 AM | Permalink | Reply

I quit taking the welbutrin and I am SLOWLY getting back to normal. The numbness, tingling, and electric shocks are pretty much gone. I just mentally do not feel right yet. I was wondering how long it takes for you to mentally get back to normal after quitting. I still feel extreme anxiousness and paranoia.

Posted by Saya on March 18, 2008 2:30 PM | Permalink | Reply

I've been on WBXL for 6 weeks now. In the beginning, i had the dry mouth and awful taste in my mouth. that went away after a short time. My biggest problem is sweating and body odor. i love the way the drug makes me feel, I am actually happy again but i'm still waiting for these side effects to stop. Please tell me that it will.

Posted by Kim on March 19, 2008 9:48 AM | Permalink | Reply

I've been taking brand wb 150sr for a little over a week, and it's completely different from the terrible experience I had with the generic. If you are having trouble with the generic, throw it in the trash and insist on the brand. I am getting the brand in the mail from Canada, which is the only way I could possibly afford it.

Posted by mari on March 19, 2008 9:12 PM | Permalink | Reply

I had a severe anxiety attack and blacked out at work and fell down a staircase. My Dr put me on lexapro, xanax,when he felt those weren't working he then put me on wellbutrin XL ontop of everything else. Within 2 weeks of starting the wellbutrin I started having suicidal thoughts and started cutting myself. When I went to see him to show what was happening to me and tried to tell him I felt like I was going crazy, he took me off the wellbutrin and xanax cold turkey and I crashed.It was hell for me! He really didn't seem to care what I had done to myself like he had seen this happen many times before. I do not recommend anyone taking wellbutrin XL!!!!!

Posted by Caitlin on March 20, 2008 6:25 PM | Permalink | Reply

I've been on Prozac and Lexapro and gained 18 pounds in a year, and I have a small frame. I went to a new doctor and they told me with my symptoms I shouldn't have taken those pills. ( I was very upset because the weight gain). He put me on Wellbutrin SR 150mg. Its been 4 weeks and I feel pretty good. The first week and half was so bad for me. The constant dry mouth, nauseau, not eating, still having mood swings. Then it all just stopped and I feel great, I don't get upset easily, don't make up horrible stories in my head, not losing my temper, AND STOPPED SMOKING :) O ya, I have lost 5 pounds too!!! I love it, but I think everybody has different side effects, etc. Good Luck to all, and make sure you talk to your doctor about what you should take,so you dont get screwed:)

Posted by Kathy on March 21, 2008 12:24 PM | Permalink | Reply

Late October I was prescribed Wellbutrin XL for depression. It started with a week of 150MG then went on to 300MG. 3 weeks later i started feeling drowsy all the time, after 6 weeks I could not form sentences, was confused and delusional, had tremors, and multiple other symptoms. I went to the hospital where they checked me for tumors and said to stop the WB. A week of 150mg later i was off of it.

Now it is over 3 months later, and I still have neurological issues that I have never had before. I have trouble focusing 24 hours a day, which sometimes gets really bad for long periods. Constant headaches, drowsiness no matter how much I sleep. and sometimes tremors.

no doctor has been able to help me, and these problems are greatly effecting with my life. to the point of having trouble with school and getting jobs.

Does anyone know if wellbutrin could be the problem? We have searched in every other area and no answers seem to come up.

Posted by Allie on March 21, 2008 5:20 PM | Permalink | Reply

I started taking prozac in 1987 for bulimia. It was a god sent. But after giving birth to twins(1999)I never felt ok. I had constant sucidial thoughts. I upped the prozac, felt better, then the same thing. not depressed, but very anxious, and intrusive sucidial thoughts.

I will skip a lot of attempts at medication (and a diagonis of bi polar 2 which I am not).

I stopped the prozac and started wellbutrin 150mg for 1 week and increased to 300sr (or xl) the 2nd week. Let me be honest and say that I thougt I was going to hurt someone....very aggitated and mean. I had some xanex that I took as needed....

Today, I am on Wellbutrin 300sr and doing great. However, the wellbutrin does not help with my 'worry' and I have figured out that if I take prozac 20mg 2 times a week the anxity/worry is manageable.

I can not began to tell how WELL I feel and how different my life is.

Hope this helps someone.

Contact me if needed.

Posted by cr on March 22, 2008 6:00 PM | Permalink | Reply

Hi everyone I am like sabrina I just started taking wellbutrin 150mg sr and now i am getting a little worried about the side effects. First i have to take one pill aday for three days then starting with the fourth day i have to take two pills one in the morning and one in the afternoon. This is day two for me and I have'nt had any side effects as of yet. But I plan on talking to my Doctor in more depth about the side effects. Now I have heard from a friend of mines that her doctor said that she should take it for weight loss. Is this true?


Posted by kim on March 28, 2008 8:21 AM | Permalink | Reply

Hi everyone I am like sabrina I just started taking wellbutrin 150mg sr and now i am getting a little worried about the side effects. First i have to take one pill aday for three days then starting with the fourth day i have to take two pills one in the morning and one in the afternoon. This is day two for me and I have'nt had any side effects as of yet. But I plan on talking to my Doctor in more depth about the side effects. Now I have heard from a friend of mines that her doctor said that she should take it for weight loss. Is this true?


Posted by kim on March 28, 2008 8:23 AM | Permalink | Reply

For Jess, Re Regression

I felt the same way you felt at about 6 weeks on XL. Keep taking them, you will balance out. Trust me. You are adjusted to the meds so the effect seems less intense.

Posted by edem-enang78 on March 31, 2008 12:56 AM | Permalink | Reply

elaine (Posted March 5th): Obviously, the symptoms you describe point to a depressive disorder. Please make an appointment with your family dr. and discuss your options. Your fear of medicating your depression may actually be a presentation of an anxiety disorder.

Mood and anxiety disorders frequently overlap. Both are treatable.

I don't mean to imply that experiencing anxiety indicates a disorder. Anxiety is a perfectly normal response to stress. But, be honest with yourself - if you have powerful fears that don't seem rational, please discuss with a dr.

Posted by j on April 1, 2008 12:18 PM | Permalink | Reply

I have a 15 year old son who had been on w xl 300 for for 6 years. A year and a half ago he was diagnosed with bipolar, it has been a year from hell revamping meds. Upto 2 weeks ago he was still taking 300 xl, and has been having horrible hallucinations for about the last 9 months with up and down manic swings that would make your head spin. His Dr informed me that all the chaos was caused from his w xl. Has anyone else every experienced anything like this?

A Mom

Posted by De on April 2, 2008 7:43 AM | Permalink | Reply

Hi all- I started taking wellbutrin SR 150 once a day about 5 days ago. I'm doing pretty well, have nausea for about 2 hours after I take my dose, my ears are ringing, but I can deal. My main ? is.... when do the side effects stop? I'm going on about 4 hours of sleep and feel okay, but how long do I need to give this? I'm laughing more & seem more carefree already-not excessive though- I guess I'm just wondering how long the nausea and insomnia will last? Are we talking months?

Posted by Sarah on April 2, 2008 4:41 PM | Permalink | Reply

I started taking Wellbutrin Xl 150mg two weeks ago. At first I was fine but then my doctor upped my perscription to 300mg and thats when my life turned into hell. I've been nauseous, dizzy, tired, weak, and just completely out of it. The symptoms remind me of flu like symptoms with body aches and headaces. Unfortunately, my doctor has been MIA since he upped my dosage and now I'm not sure what do to. I decided to cut the pills in half and take them every other day instead of every day but I feel even worse. I can't function and I don't know what else to do.

Posted by Jennifer Condron on April 3, 2008 5:53 PM | Permalink | Reply

I've been taking generic WB SR since last Thursday; spent the rec'd four days at 150, then increased my intake to 300 mg twice a day.

I'm currently in college and insanely busy. I work extremely hard and have trouble with insomnia for quite some time--script sleeping pills don't even phase me. Anyway, I've gotten about eight hours total sleep in the last week--which I know is scary unhealthy. Also have lots of stomach clenching, which has made it impossible for me to hold down food; the dizziness is scaring the crap out of me...just managed to fall asleep earlier and woke with the worst vertigo feeling of my life. Anyway, I was wondering how much long these symptoms will last...they're scaring the crap out of me. I've been on other meds before and completely believe that the adjustment time is well worth the effort, but I'm scared.

Posted by mimi on April 4, 2008 2:31 AM | Permalink | Reply

I have been taking 150 mg Bupropion (Welbutrin) daily for the last 2 years. Crying and sadness resulted this week in my doctor supplementing this with 30 mg of Cymbalta.This has left me tired, a feeling of being "high" and sleepy. Has anyone else been on a combined diet of these 2 drugs? and if so what are your results?

Posted by Ty on April 4, 2008 10:07 PM | Permalink | Reply

I've been on Wellbutrin 300 for about 2 years for anxiety and it has done well for me. I am concerned about any long-term use side effects. Does anyone know if it is one of the drugs that can lead to Parkinson's - I have heard that some anti-depressants can do that. Are there any things to be concerned about?

Posted by Carole on April 12, 2008 6:00 AM | Permalink | Reply

Regarding comment 443: I was like you, not sleeping at all. When I took Wellbutrin XL it got worse. My doctor prescribed 3 mg of lunessa each night. I took them for about 2 weeks. I sleep fine now. I know you said script sleeping pills didn't work. If you haven't tried Lunessa, please do.

Posted by edem-enang78 on April 12, 2008 9:22 PM | Permalink | Reply

445 comment-- Give it time, your body takes time getting used to it and after a couple weeks you will start to feel great. I've been on it for over a month and I love it. I have lost my 13 pounds that I put on taking Lexapro and Prozac, my mood is great and I always feel motivated :) Just see what happens.

Posted by Kathy on April 14, 2008 10:57 AM | Permalink | Reply

Wellbutrin does cause an increase in anxiety/irritabilty in many people. I have been on it for 5 months and it sure has increased my anxiety. I was already rather irritable.

Posted by Gregory Gauthier on April 21, 2008 12:05 PM | Permalink | Reply

I get my prescription from Canada (only way I can afford it), started off with 150, now am on brand 300 XL. I was doing a little better after a few weeks but was not great. Because I didn't reorder in time, there was going to be a small gap so my doc gave me a script for 10 which I filled at my local pharmacy. The pills look totally different, the U.S. ones are large, oval and tan, the CN ones are small, round and white. But the biggest diff was the U.S. ones DID make me feel great. Then when they ran out I went back to the Cn, after a couple days I started feeling really bad, kind of like the flu but with a very fuzzy head and confusion about the simplest things. I was wondering if any of you have gotten their drugs from Canada, or if there are any Canadians out there who would know something about this. Thank you.

Posted by Mary on April 21, 2008 5:00 PM | Permalink | Reply

response to comment 446, i found this article that talks about the link between anti-depressants and Parkinson's, i.e. there is none. Here is a link to the article:

I have been on Wlebutrin for about 6 weeks now. I notice my muscles are really really sore and stiff, and my irritability levels are the same as before I was taking an SSRI. The SSRI left me feeling tired all the time. Welbutrin has upped my energy level, I have lost some weight, and am not totally without libido. However, along with the irritability, I have also had one depression episode like those I had before seeking any medical assistance. It was only once, and seemed to be linked to not taking the pills EXACTLY 6 hrs apart (I am on three a day).

I am wondering if the anxiety tapers off at all? Too, I have not been diagnosed with bipolar. I have depression. Is anyone else who is depressive with no manic curve posting here?

Posted by Michele on April 25, 2008 2:25 PM | Permalink | Reply

I just started taking this medicine. I've had problems with premature ejaculation that I've never spoken to the doc about... I just deal with it...

However, it seems to have gotten worse with this medicine. I don't see it as a side effect, so I'm just wondering if anyone else has this problem or if I'm just imagining it. Kind of embarassing to discuss with the doctor either way though.


Posted by Anonymous on April 29, 2008 8:13 AM | Permalink | Reply

I began taking 75mg daily of Wellbutrin about 3 weeks ago.

I am noticing my Meniere's disease symptoms increasing.

Coincidence? Anybody have Meniere's that is taking Wellbutrin?

Posted by Christine on April 29, 2008 9:07 AM | Permalink | Reply

Hello Everyone,

I have been on the generic Wellbutrin 150 for almost 2 years now, and decided I am going to wean myself off. I am really scared though about side effects. I don't want to start feeling depressed again. Does anyone have any advice or stories about taking Wellbutrin for this long and then stopping? I would appreciate ANY stories or precautions. Thanks everyone!

Posted by Lexi on May 1, 2008 11:14 PM | Permalink | Reply


Posted by PAULA on May 12, 2008 1:57 PM | Permalink | Reply

I’ve been taking wellbutrin for about a month and one week. I love this medicine my doctor prescribed it to me so that I could quit smoking. The first 2-3 weeks you do suffer a lot of high levels of anxiety but after that you’re good too go. I have successfully quit smoking and its been about 3 weeks that I have not touch a cigarette, I haven’t lost weight but then again I haven’t gain either which is a plus because after you quit smoking you tend to find happiness in food LOL. I am very content with this little pill I would recommend it to anyone that lives a very hectic life style because it has given me energy and I focus better then ever.

Posted by yvette on May 15, 2008 11:04 AM | Permalink | Reply

A month ago my meds were increased to 600mg of Wellbrutin XL. I'm a senior and want to know the effects of this medication on an old system.I can't seem to find any information. I have memory lapses, seeing double, (I just had my eyes checked recently.), hungry all the time, tired, have lost interest in things I used to love. I'm tired all the time.

Is there anyone out there who have had these symptons? Joanne

Posted by Joanne on May 17, 2008 10:15 PM | Permalink | Reply

I have been taking Wellbutrin SR 150mg x 2 but just realized I should have been taking them at least 8 hours apart vs ONCE in the morning. My concern is that I have been having mild "electric" shock-like stuttering. Ironically, I have Social Anxiety so it seems to happen only when I get nervous or excited about what I am talking about. I also used to have horrible nightsweats until I stopped taking the Paxil. My main concern is that I wonder if the "electric" shock-like stuttering is a precurser to having an all-out seizure. I have other tolerable side effects as well: mild lethargy and oddly enough happy nostalgic crying spells. Hopefully, taking the 2 Wellbutrin SR TWICE instead of ONCE will help. Anyone out there had any of these experiences or have any advice for me?

Posted by Getting Better on May 21, 2008 8:38 PM | Permalink | Reply

I am dealing with severe sleep deprivation and post partum. My doc gave me W XL to take and I am such a bear to live with. I started it 6 days ago (150 mg) and have never been so agitated. Please tell me that it gets better! I feel badly for my husband and baby b/c I am not a happy person, can't sleep and don't want to be around anyone. This is not who I want to be....

Posted by New Mom on May 24, 2008 4:17 PM | Permalink | Reply

I started taking Wellbutrin for Depression about 3 years ago. I did like to Gamble, but never had a problem until taking this drug. I have lost about 500,000 in the last 3 years and just thought I was crazy and compulsive. I funally thought it might be the drug and stopped taking it. I have not gambled now in 2 weeks. I was gambling everyday. This drug also caused me to have panic attacks and I was put on Klonipin for the Panic attacks. I did not even know the drug had this side effect. Now I am trying to get off of the Klonipin, but when I try, I get really anxious. Has anyone experienced the Compulsive behavior or Panic attacks.

Posted by Kim on May 26, 2008 10:45 AM | Permalink | Reply

Post 470, I've been taking 300mg for about two months. I also was agitated in between my first and second week, but after that it seems nothing can really agitate me. It's actually quite nice :)

Posted by Drew on May 27, 2008 9:45 AM | Permalink | Reply

I have been taking WB for three weeks - 150mg for seven days then 300mg thereafter. I have an awful taste in the back of my mouth that feels hot like. Very weird but I can't explain it - it's definitely not dry mouth. I also have been VERY agitated and some slight nausea and heart palpatations. Has anyone had the mouth side-effect?

Posted by Brenna on May 27, 2008 5:51 PM | Permalink | Reply

HI there, I've just started taking WB this week - 150mgs - along with 30 mgs Prozak.

I have had the most massive headache since taking it.

But I'm nervous about taking Tylenol or Advil with this new medication.

Any thoughts?

Posted by beth on May 29, 2008 10:57 AM | Permalink | Reply

I'm new to this forum but it has been fascinating to read everyone's posts. I've been on 100mg 1x a day for 3 weeks now. I actually feel pretty good aside from the daily headache situation. I've been having horrible headaches for the past 3 days ALL DAY. I am crossing my fingers that this will subside because otherwise I feel more like my old self than I have in a long time. I'm laughing again, I have more energy and motivation to get things done, and I am starting to remember all of my old interests that I didn't know I had ceased to enjoy. It has been so strange to go through this process. It's like I am just NOW realizing that I have been depressed for about 2 years even though friends and family have known this to be true. I'm shocked at having my old self back.

Posted by Julia on May 30, 2008 4:26 PM | Permalink | Reply

Has anyone here had any experience with body/muscle aches? After having somewhat severe aches I finally researched and founf that is indeed a possible side effect. thinking I will stop taking

Posted by Chris on May 30, 2008 6:44 PM | Permalink | Reply

Hello, I have been taking Wellbutrin XL 300 for about 2 weeks now. About 2 days ago I started getting these strange "dream-like" sensations. I feel totally out of it, like I'm in a fog. Then I will just snap out of it. Does anyone else suffer from this? It is very scary, and I don't know if it's normal. It seems to be followed by a rapid heart beat, but I'm assuming that is from being scared rather than an additional side effect from the drug. Please help if you can!

Posted by Allie on June 8, 2008 5:39 PM | Permalink | Reply

Allie, I felt like that on WXL 300, it's not pleasant. After a few more weeks passed, I started getting the heebie jeebies real bad so I called my doc and he called a new prescription for XL 150, and now I'm doing much better Don't have that spacy feeling at all now. P.S., don't try cutting the 300 in half like I did, that causes another whole set of problems.

Posted by Mary on June 10, 2008 3:54 PM | Permalink | Reply

Hi I am hoping someone can answer my question. I was on Wellbutrin XL 150 for about 5 weeks. Headaches went away and was doing pretty well. My doc upped the dosage to 300 and it's been 1 week. I was fine the first few days but the last 2 days or so I am itchy. Has anyone else had this and if so does it go away? ANY help/advice would be SO helpful and appreciated. Thank You.

Posted by GM on June 11, 2008 4:23 PM | Permalink | Reply

To Joanne post 467. As far as I have read 450mg is supposed to be the maximum dosage. I had read as well that seniors metabolize most drugs at a slower rate. Please speak with your physician or get a new one being on that high of a dose is dangerous to your health

Posted by mya on June 12, 2008 12:35 AM | Permalink | Reply

I am going to start WXL 150 this weekend. I was told by my Dr. to reduce the Celexa I am on to 10 mg. for a week before starting WXL. She is taking me off the Celexa because I had a retinal hemorrhage and I guess Celaxin and simalar meds can cause increased bleeding. After reading all these posts I am afraid to start the WXL. Has anyone done well with this without all the crazy side effects? I also have acid refux, can this make that worse?

Posted by Lynda on June 12, 2008 5:49 AM | Permalink | Reply

Post 486

I experienced the same symptoms initially, but then they went away. (probably after about 6-8 weeks.)

Post 480 The itchiness happened to me but only in my vajay-jay. (Sorry, if I've grossed anyone out.) It was bad, I freaked and ran to the doctor, as I was sure I had an STD. She examined me and found nothing, no bumps, no redness and no irritation. 3 days later it went away. I had been on 300 mg of WXL for about 2 weeks at that point.

Post 448
Take 2,000 mg of Biotin vitamins per day and the hair thinness/loss you are experiencing should improve (at least mine did.)

For the senior who is taking 600 mg of WXL? Contact your doctor. I was under the impression that the max daily dosage was 450.

Finally, an update. I'd been on 300 mg of WXL (generic) for about 7 months. The first 6 months my mood and sense of well being improved greatly. Month 7, the apathy returned, then the irritability, lingering sadness, crying jags and finally I was stuck back in bed again. I freaked, as I began to have suicidal thoughts and I kept thinking, how can this be happening, when I've felt so good until now. I'd even lost 30 pounds! I was a size 13/14. Now I'm a size 9/10 and am still losing but at a slower rate.

My psychiatrist increased my doasgae to 450 mg/day 3 weeks ago. I am beginning to feel better. I was so scared as I'd just started a new job after being laid off for a year. I could hardly afford to call in sick..... Anyone else experience a relapse like this?

Posted by edem-enang78 on June 24, 2008 6:46 PM | Permalink | Reply

This is my third time on Wellbutrin and it's not going as well as it did the first two times. I have experienced fatigue and muscle weakness, which did go away after two days. Now, I am also experiencing joint and muscle pain, Chris; and the dry mouth is non-stop. I've been on 150mgs for 9 days now and I'm still hoping that the side effects will cease because the medication is making me think much more clearly and rationally. I should say, however, that my first two times on Wellbutrin was to help me quit smoking - which I did. This time I am on it for my anxiety problems...so it is possible that I experienced some of the same side effects the last two times I took the medicine, but just didn't realize it. Now, that I'm such an axious mess, I feel EVERYTHING that is happening ot my body. I'm glad for this forum...I'd probably think I was dying if I didn't see others with the same side effects.

Posted by amy on June 26, 2008 1:24 PM | Permalink | Reply

Just started generic Wellbutrin XL for the third time last week.I just had that old feeling that something was pressing on my chest and I was not the usual happy person.Side effects are insomnia (big time), ears ringing, dry mouth, sweating,but the one I am most concerned about is the short term memory loss.I am a little scared about this because I have to be sharp at work. Will this improve the longer I take it. Also, my doctor told me that I could have a glass of wine once in a while.

Posted by Georgianna on June 27, 2008 4:30 PM | Permalink | Reply

I was mistaken in my wellbutrin dosage, it is 150 mg, but I will be going on the generic bupropion when I finish my wellbutrin xl 150. Hope there won't be any differnece

Posted by Linda on June 29, 2008 4:53 PM | Permalink | Reply

This is my second post...it's now been two weeks since I started the wellbutrin xl and I have to say that I am doing much better! The fatigue and weakness only lasted a couple of days, and, even though the joint pain is still there, it's lessened and is definitely bearable. My mood is about 100% better, and I don't feel the same impending doom that I did just last week. The dry mouth continues, but I can definitely live with that. Glad I stuck with it.

Posted by amy on June 30, 2008 8:47 AM | Permalink | Reply

I have been taking generic Wellbutrin for 6 months and have noticed the metallic taste in my mouth getting worse. I wake up sick to my stomach. Short of stopping the generic for the real thing, has anyone heard of a remedy to ease the metallic taste...herbs, etc?

Posted by Bee on July 1, 2008 3:47 PM | Permalink | Reply

I thought the wellbutrin was making me feel better, but I hit an all-time low yesterday and rushed to see my doctor. I told her that I was experiencing, not only fatigue and joint pain, but was now getting very depressed (which was unusual since I started taking it for anxiety NOT depression). She stopped the wellbutrin and put me on paxil. I have to say that not taking the wellbutrin for even this one day has made me feel a million times better! Paxil is making me a little tired, but nothing like what the wellbutrin did to me. Hopefully, I will just continue to feel better and better. This pill worked for me in the past to quit smoking...I wonder if the reason you take it changes the usefulness of the drug. Just a thought...

Posted by amy on July 3, 2008 10:32 AM | Permalink | Reply

I have NOT STARTED 100MG ER Wellbutrin YET b/c the doctor and three pharmacists cannot agree on whether I can CUT the pill into quarters. I have to be very careful with new meds, so she wants me to take only 25 mg (cut the ER into 1/4's) and take ONLY the 1/4 a day in the AM. She said I would be FINE. BUT all three pharmacist are telling me NOT to do it or I could have a seizure or other bad symptoms. Help!? Has anyone else had to cut the XR and had a problem - or not?

PLEASE email me :)

Posted by Sandy on July 8, 2008 8:01 PM | Permalink | Reply

so grateful for the post that mentions finding floating orange/yellow pill in stool. I experienced the same.

Posted by t on July 12, 2008 8:58 PM | Permalink | Reply

you should all know that there is a good chance that if you apply for health insurance and they know you are taking wellbutrin, depending on the dosage, there is a good chance that you will be turned down. Just FYI.

Posted by t on July 12, 2008 9:01 PM | Permalink | Reply

Does anyone know anything about wellbutrin causing kidney stones? I have always been prone to bladder infections and recently i got a bad one that took two rounds of antibiotics to clear up. When the results of the culture came back, the doctor said he saw signs of kidney stones, which i have never had before with any of the other bladder infections. I know wellbutrin can be dehydrating, so i'm thinking maybe that leads to stones? If anyone else has had this issue, i would like to hear from you. Thanks

Posted by sheila on July 14, 2008 6:07 PM | Permalink | Reply

Hello everyone,
I just started taking WBXL 300mg about 12 days ago. I had been on Remeron for at least 5 years, and then switched over because the Remeron made me so groggy, I had a very hard time getting out of bed.
I have been having what seem to be unusual side effects, and I'd like to know if anyone else has experienced anything similar. I am wondering if it's possible these side effects might shift if I just tough it out for awhile.

My back , neck and shoulders feel hot. My throat is a bit sore, and my glands swollen. My mouth, tongue and lips feel hot, tingly, almost burning. ( But not swollen )And I am salivating more than I thought possible, all day and night.

The good part is that I'm jumping out of bed a few hours earlier than I have for so many years. My mood is good, emotions normal, energy ok.

Would love to hear any feedback.

Posted by Jennifer on July 25, 2008 6:44 PM | Permalink | Reply

My doctor increased my WB XL to 450 mg, which alleviated suicidal thoughts and my general despair. However, the apathy remained. Enter Celexa, 10 mgs for 10 days, and then 20 mg combined with XL 450 mg. How do I feel? Still apathetic, though it will be 10 days with this combo tomorrow. I know it can take weeks before I see improvement. My impulsiveness is nipped in the bud. I'm calmer, and not as quick to anger, save PMS days. My stomach is a little wrecked, gassy, and bloated some days. I sleep better. I'm not stuck in bed all day, and have not had anymore crying jags. I'm gonna ride the side effects out.....

Posted by Anonymous on August 2, 2008 12:41 PM | Permalink | Reply

I've been on Wellbutrin since March and at first I had trouble sleeping and would have really weird dreams. I still have some weird dreams sometimes but my sleeping is better. But I noticed since I have been on this drug my concentration level is poor. When talking with someone sometimes I lose my trane of thought many times throughout the conversation. And I know this is a side affect. I'm taking 150mg each day in the morning. I use to be on effexor but that just made me psycho and want to hurt myself. This drug has helped me alot in many ways I dont have thoughts of suicide that often which is good. They are less frequent now. I wanted to ween myself off this drug because i feel better than I use to but my doctor has said no I need to do the usual time 6 months - 1yr so I dont have a relapse but i'm hoping im off them soon!

Posted by Lisa on August 6, 2008 10:05 AM | Permalink | Reply

Oh yes I forgot to mention that since i've been on this drug I cannot cry anymore! And believe me sometimes I wish I could! Has this happened to anyone else?

Posted by Lisa on August 6, 2008 10:18 AM | Permalink | Reply

Just a thought? When u ween urself off welbutrin do u still get these electric shocks I hear people talk about?

Posted by Lisa on August 6, 2008 10:33 AM | Permalink | Reply

Ok, so I just started taking WXL 150. Mostly for anxiety, but also for a few odd obsessive tendencies lately. It has been one week exactly and up until today I was feeling fine. This morning, I started feeling majorly depressed with absolutely zero energy...and add to that muscle aches. How long before this passes??

Posted by Daniel on August 9, 2008 10:46 AM | Permalink | Reply

Hi all, Just wanted to share a few thoughts. I am diagnosed with Obsessive Compulsive Disorder and extreme depression and anxiety disorder. I have tried several meds to for about 8 years now. For the crying I finally found out that Cymbalta is a life saver!! Xanex for the anxiety. The Dr. put me on Wellbutrin 150 once a day and people around me kept asking me if I was ok. I felt fine inside but a bit as if I was drunk. Light headedness when I stood and real dopey feeling. Just wanted to forewarn that these 3 meds to not mix well together. At least in my experience. =)

Posted by Il in Georgia on August 10, 2008 5:50 PM | Permalink | Reply

I have read all the posts from 1-512. What gets me is that all of the symptoms (except itching) I have lived with for 3 years...not due to any medication. Last week I finally went to a endocrinologist to have everything checked out. I wasn't planning on this, but he put me on Buprion 75 mg (twice a day) for being overweight and smoking problems. I had gone in for physical problems and was put on an anti-depressant. The blood test results came back and im NORMAL. Well, I don't feel normal! Ends up..I probably have been depressed for a few years and didn't want to admit it. I just kept pulling through, fighting against each day. So I am happy to be put on this. It will be a week on Thursday that I have been on it. Waiting to see what happens. But if I experience any of those side effects...it will be like how I feel normally anyway. I am hoping that it will help me quit smoking, and help me have motivation to excercise my weight off, and help me look at life positively instead of just a 24/hr sucky job.

Posted by Cris on August 12, 2008 2:44 PM | Permalink | Reply

Its 3 am .. and I am wide awake... Thank you Welbutrin .. ha ha... well I have been on welbutrin for about 3 weeks now... the doctor started me out on 100 mg twice a day. My thoughts are torn with this medication.

Pros: more energy, not starving all the time. I am a mountain dew addict and as soon as I started taking it I didn't want the dew anymore.

Cons: im awake at 3 am, I had to stop taking the morning dose of Welbutrin because about mid morning i would feel drunk and could not focus on anything. I could cry over every little thing and my kids think i've turned into some b**** from he** that they just met. where did my mommy go.

Prior to this I was on Zoloft for 6 years. I love my Zoloft because it takes the edge off my anxiety, however it made me not give a flip about anything ha ha... i didn't care if my house was clean or what anyone else thought about anything.. Now I'm a woman obsessed. My house can't get clean enough. I sit and think about what else needs to be done before I lose my mind. I love a clean house and the energy I have, but which is better or worse. I can't decide if I should continued taking it and get no sleep and have lots of energy. or go back to the zoloft when i was such a nice laid back person.

it is all so confusing

Posted by Barbara on August 13, 2008 1:10 AM | Permalink | Reply

okay, i know it's terrible, but i took Wellbutrin XL a few years ago and realized I probably needed it again so started taking the pills without a doctors say-so at 300 mg. I've been on it for a few days, and yesterday I was extremely fearful for no reason at things that didn't make sense to be afraid of. I also got all of 2 hours of sleep last night, and I have that terrible cotton mouth. I was wondering, should I just stop taking it? Or could I cut it in half, or is that dangerous? OR will the side effects go away on their own? Please help!

Posted by Ikin on August 14, 2008 7:55 AM | Permalink | Reply

Trileptal was given to me. It made me forget things. Also, it took me a month to stop being nauseous. I sometimes wonder if trileptsall caused me to get irate quicker. Lamictal is much better. I never got sick from taking it. I'm wondering if the generic from Dr Teddy is causing me to be really tired. Or if it's the generic Wellbutrin SR I'm taking. I wasn't like that when I was taking the generic by Zydus.

Posted by Karen on June 4, 2012 5:44 PM | Permalink | Reply

Those are not pills persay. The XL's are actually a patented delivery system and are not to be cut or sectioned.

Posted by Gregory Gauthier on August 14, 2008 3:00 PM | Permalink | Reply

Well I've decided to wheen myself off wellbutrin the memory thing is happening alot! And I dont like it I need my memory for my job! I've been having sleeping problems so I've been taking a sleeping pill at night to sleep. I started last thursday every other day been feeling tired and cranky this week.Also been depressed and friends are giving me grief about this but my choice! Just not feeling myself this week.

Posted by Lisa on August 17, 2008 4:42 PM | Permalink | Reply

ok, i have read comment after comment and it looks like there is more bad comments made for this drug.
My doctor has put me on this drug as post pardum relief. im going to be taking 150 a day 75 in the morning and the other in the evening.. now im scared.. what i think is going to help me may actually make life hell..
right now im argumentative sad depressed and angry.. aggitated and want relief from that..
did this help ANYONE! i want my family to love me again.. not get even more frustrated with me!

Posted by missy on August 18, 2008 10:29 PM | Permalink | Reply

ok...please somebody help me. I have been on wellbutrin for over a month and I am in complete hell/ My life has been turned upside down. please does anyone experiance this weird feeling in ur head...kinda like lightheadedness. I can feel my pulse through out my body and these feelings are pulling me down so bad. I go around like im not myself, and like i have no brain in my head. It scares and it feels like i am going to never be rid of this. Does anyone knowexactly what im talking about. I just wanna know that im not alone in this????

Posted by Kalee on August 19, 2008 6:47 PM | Permalink | Reply

ok...please somebody help me. I have been on wellbutrin for over a month and I am in complete hell/ My life has been turned upside down. please does anyone experiance this weird feeling in ur head...kinda like lightheadedness. I can feel my pulse through out my body and these feelings are pulling me down so bad. I go around like im not myself, and like i have no brain in my head. It scares and it feels like i am going to never be rid of this. Does anyone knowexactly what im talking about. I just wanna know that im not alone in this????

Posted by Kalee on August 19, 2008 6:48 PM | Permalink | Reply

WXL 450 mg and Celexa 20 mg has proven to be helpful. Save a dull headache that occurs every few days, and constant yawning from the morning to late afternoon. It mysteriously disappears at night. My sleep is better. Initially I'd wake up 2 or 3 times through out the night. I'm able to get to the gym atleast 3 days a week (major improvement, before I'd only think about going) I'm continuing to lose weight. I'm between a size 8 and 10 now. Size 10 is too big, but I'm not able to fit comfortably in a size 8 yet. Again, if you can ride the side effects out, WXL could work for you.

Posted by Anonymous on August 19, 2008 8:04 PM | Permalink | Reply

I just posted 526. I forgot to mention that I can talk myself into going to do things I wouldn't normally do, like go to a party where I only know one person. Usually I avoid situations like that.

Posted by Anonymous on August 19, 2008 8:11 PM | Permalink | Reply

I am a 33 year old female and I have been taking WB XL 300mg a day for 3.5 months for depression and irrability. At first I could not sleep or stay asleep. This went away. It seemed to be working, but now I am obessing over death - not killing myself, but overcome with this realization. It is something that is always on my mind. Is this the drug doing this?

Posted by SC on August 22, 2008 6:37 PM | Permalink | Reply

I have been taking WBXL for well over 6 years now. I don't find that it makes a huge difference in my mood. However, I SWEAR by this drug when it comes to quitting smoking. Don't get me wrong, you still have to have the willpower, but it makes it sooooo much easier. Also, it is great if you want to loose weight, but you have to work at that too. Better diet and exercise, but it is a great boost to your weight loss goals. I have had to stop taking a few times over the past few years for one reason or another. Although I don't remember any withdraws, I will say that when I began taking again, I was very irritable for the first few weeks. BTW, I'm on XL 300 ml. Also, beware fo the generic form of this. I have had to take the generic at times for pricing reasons. The pharmacy will tell you that generic are no different, don't take their word for it. I mentioned to my Pharmacist that I didn't think they did anything and she didn't beleive me. Not to my suprise I saw a study that they televised saying that Welbutrin XL generic has been proven to not work as effectivly as brand name. So if you have a choice, with this one, go brand name.

Posted by Rebekah on August 26, 2008 6:20 AM | Permalink | Reply

I also have an overwhelming thought of death and I'm taking Wellbutrin 300 XL. I've been taking Wellbutrin for 8 years now and I think my depression and anxiety is breaking through. My MD wants to add Luvox because she says the Wellbutrin really isn't for anxiety but I am hesitant in taking 2 drugs.

Posted by JR on August 26, 2008 5:01 PM | Permalink | Reply

I was on Wellbutrin for 9 years and finally just realized that it was that causing my anxiety. I quit cold turkey a month ago and I feel awesome. My husband can't believe how calm and happy I am and I don't think I'm dying of every disease out there anymore! I went to a naturalpath and she put me on a hyperglycemic diet. I stay away from sugar, pasta and rice and eat alot of protein and my mood swings and depression isn't controlling my life anymore. This won't work for everybody so I don't reccomend anyone doing it without talking to their dr. My dr still doesn't believe that I'm ultra sensitive to sugar...he just wants to keep pumping me full of pills!! good luck to everyone out there!

Posted by HK on August 26, 2008 5:28 PM | Permalink | Reply

Thank you 531 for your comments! That's exactly how I am; thinking I am dying of every disease. I am seeing my doctor on Friday and I am going to tell her I would like to wean off. I'm very sure this medicine is not helping me anymore. I would like change my diet also. I think that would help. Thanks again!

Posted by JR on August 26, 2008 6:23 PM | Permalink | Reply

I have read some of these posts yet am in the middle of Wellbutrin HELL and not knowing what to do. I have been taking wellbutrin for a month after a terrible withhdrawal from Effexor (it seemed to stop working) Since being on the Wellbutrin I feel like crap. I have 2 kids 4 and 7 and have found myself so short with them, I have made them cry and they both really dislike me right now. I have a dizzy??/foggy?? feeling all the time. Occassional head spins. I am sweaty and shakey most of the day. I thought at first it was just adjusment to the drug - now I am worried. My husband and mom think I am nuts and are done with me not being able to deal with the children. My husband makes his own hours but does need to attend to his clients. A call to my Dr. today out of sheer panic that I was going crazy resulted in him prescribing an anti-anexity on top of it. I am nervous about taking that too now. I am thinking about stopping it cold turkey myself and hoping for the best till he is back from vacation. Any thoughts or has anyone else gone through this. I am worried for my kids that I will snap and just walk out! (it has been a thought) - sorry so long....I am deperate for answers!

Posted by Kris on August 28, 2008 2:39 PM | Permalink | Reply

Kris- I am in the SAME boat you are in..sweaty, crabby, short tempered. I have been on it for about 5 days now...it is progressively getting better...how long have you been on it?? I heard that it will taper off.

Posted by Misti on August 28, 2008 2:57 PM | Permalink | Reply

Hi Misti - I am going on a month and a half now. My symptoms seem to be getting worse as the days progress. I know that every drug is different for every person so if your symptoms are decreasing it sounds like folks here would tell you to stick with it. A friend of mine Loves wellbutrin with no side effects.

So I hope you are feeling better soon. I am still looking for answers. :(


Posted by Kris on August 29, 2008 12:35 PM | Permalink | Reply

Hi Misti - I am going on a month and a half now. My symptoms seem to be getting worse as the days progress. I know that every drug is different for every person so if your symptoms are decreasing it sounds like folks here would tell you to stick with it. A friend of mine Loves wellbutrin with no side effects.

So I hope you are feeling better soon. I am still looking for answers. :(


Posted by Kris on August 29, 2008 12:35 PM | Permalink | Reply

Hi, I'm a noob to this post. I've been reading the posts and found it to be very interesting. I recently survived a blot clot to my leg that spread to my lungs. I'm 37 male and was a smoker, my job is high stress and marriage of 23 years is on thin ice. I have 3 awesome kids, very supportive they are. I quit smoking after being hospitalized for dvt/pe and was put on budeprion sr 150mg at first daily now twice daily. I've been on it for 5wks and urge to smoke is almost gone still think about it though, but the will to live for my kids is stronger. I'm a big guy and had a very good appetite which is now under control and am losing weight. The problem I would like to talk about is the mood swings and the emotional crying. I'm also exp. shaky hands, migrain head aches, muscle soreness especially the arms and neck and also mild chest pain, kinda like if my chest is heavy sometimes pounding then goes away, I guess I'm having difficulty handling stress at the moment which is my thing, I'm usually the guy that in the moment can get it done. At first I thought maybe its the PE(pulmonary embolism) and I'm going to have a heart attack or stroke or just die, in fact I have been to the ER a few times, only to be sent home because the vital signs are good. I feel good about quitting smoking, but I'm really concerned about these other problems its getting hard to keep things together. I'm currently on disability for 90 days and the job wants me back sooner than that or I think they will replace me, oh I'll have a job but not the same position, I don't think I can handle the job right now. I'm still feeling like I'm in trouble and will have sudden death at any time, but now I thinking about it all the time. Almost everything I feel is tripled physically and emotionally. I think I need therapy. The marriage is sinking and the the wife is not being supportive. She is afraid of me and the mood swings, like I said I'm a big dude and I can be very intimidating, even if I'm trying not to. It feels good to write this out, but I still have not talked to anyone about this. My doctor says that this will pass and tells me to stick with it. I'm trying to maintain a good face to everyone, they are still counting on me. Need a friend to listen.

Posted by Chief on September 5, 2008 11:45 AM | Permalink | Reply

Ok, this might be a weird one,,, I wouldn't call it insomnia exactly, just over stimulation.

Sometimes when I try to go to sleep if I'm feeling a little energetic when I close my eyes my eye balls roll back up and start twitching. You can tell because if there is enough light in your room the blackness behind your eye lids gets a little less dark and also it strains your eyes and makes them feel uncomfortable.

I am on 300 mg of XL and I am 2 days shy of 2 weeks. Most of my side effects have worn off but for the last 2 or 3 days I have been I bit fidgety to a degree that is uncomfortable to me and I have the ringing in my head. I also have a bit of pain in my joints, I think that is causing the fidgets because it is so uncomfortable. But only when I watch TV in the living room, if I lay down in bed I am fine, I don't feel a thing, but I still hear it...

I think I am going to call my Dr tomm and see if she thinks I should cut down to 150 or if should just wait it off...

Posted by October on September 9, 2008 1:00 AM | Permalink | Reply


And anyone else with this problem... if you are worrying more than before and thinking about death that sounds more like anxiety to me. My Dr asked me if I had it and I didn't think so but she said that if I did that she would give me something different because WB can cause anxiety. So if that is the case I would think surely there has to be a better solution than taking a drug that causes another disorder that I have read some people on here take a separate med to cancel out the side effect of the first one....

Posted by October on September 9, 2008 1:10 AM | Permalink | Reply

check out
#538 blog she posted
and other answers here.

Posted by jan on September 10, 2008 10:20 AM | Permalink | Reply

SEE POST 538, 542, 543 and 546 on your drug.

you will get worse!

Posted by antidepressants harm you on September 13, 2008 9:54 AM | Permalink | Reply

I've been having numbness in my legs and I'm taking Wellbutrin 300mg. Is anyone else having these symptoms?

Posted by JR on September 13, 2008 4:58 PM | Permalink | Reply

I've been on the generic SR for the past 2 weeks. My side effects seem to be getting worse. I have a horribly loud ringing in my ears, I can't sleep properly, but worst of all, today I feel like I'm going absolutely crazy. I can't stop crying, my mind is racing, my legs feel restless, I can't seem to think properly because my mind feels scattered, I can't sit still, I feel more depressed and sad than ever, and I feel very paranoid and scared....Has this happened to anyone? I don't even feel like myself :(

Posted by Jay on September 16, 2008 9:24 PM | Permalink | Reply

I've been taking WBXL 300mg for a week and feel absolutely GREAT! However, I do have one tiny little side effect, I know this is going to sound halarious but my back and my butt cheek will not stop itching...stop laughing, it's horrible, I know right...well anyway I kinda figured it's a small price to pay to feel good again. Hopefully it will stop in time. I noticed some people wanted to know what to expect when they go off of it cold turkey. Well, I don't advise it unless your into seeing crazy things. My friend did just that and while she was taking her final to get her principals certificate her dead father all of a sudden appeared and was sitting right beside her...yeah she freaked! She called me from the test facility totally losing it. Then a couple days later she was doing her dishes and looked out the window and saw and I quote, "a purple ape run across her yard"....I told her right then and there to get back on the medicine because she was having way too many crazy hallucinations and I've heard that does happen. Anyway hope this helps someone.

Posted by Shannon on September 18, 2008 3:43 PM | Permalink | Reply

Yes, I feel depressed and paranoid and scared in response to comment 551. My doctor still thinks I'll be more depressed by stopping the Wellbutrin 300 XL. I want to change medications or not take anything for a while and see how I am. I've been on Wellbutrin for 8 years.

Posted by JR on September 19, 2008 11:24 PM | Permalink | Reply

I've been taking the generic form of WB SR 150 twice a day for several months. I recently stopped because of my mind feeling very fuzzy. I've found it hard to concentrate. I also forget words while I'm talking including people's names. This has me worried and I'm hoping to find out soon that it was the medicine and not something bigger. If my mind returns to normal soon I do plan on trying the actual WB SR because otherwise it made me feel better. If anyone else has had similiar experiences I would love to hear about them. I read all of the threads above and did see a couple mention memory loss.

Posted by CN on September 20, 2008 9:06 AM | Permalink | Reply

ALL - SEE POST 542 AND 543 !

Get off this horrible drug and don't go back on any of them. You don't need them. Check out this blog posted on #538:
Please view this blog and share with your friends. Jena

Posted by jan on September 22, 2008 12:06 PM | Permalink | Reply

Im using it for stop smoking aid and I'm on the 300 mg and I havnt noticed any side effects from it

Posted by Justin on February 25, 2012 8:46 AM | Permalink | Reply

I have been taking bupropion 300mg once daily for 10 days. I have the worst gas pains, bloating and constipaion but the meds were starting to do their job. Dr cut me back to 150 mg once daily and now my mental state is bad again. Does anyone have any experience or ideas how to take the full dosage and counteract the side effects. Would appreciate any help.

Posted by Ruby on March 9, 2012 11:57 AM | Permalink | Reply

This happened to me when I first started taking Wellbutrin. My Dr told me to get Miralax. It is over the counter but if you get an rx your insurance may pay for it. It helps with bloating, gas and constipation. I mixed about half a regular dose of the Miralax in a glass of juice every morning and was back to normal within a few days. I kept with the half dose every morning for 2 months or so and then gradually stopped taking it and never had to again. NOTHING like a normal laxative. It's great!

Posted by Lynn on March 21, 2012 6:04 PM | Permalink | Reply

Hoping for some help! I have been reading through all of the many comments hoping to find that others have also experienced extreme sweating for no reason!! I can be doing absolutely nothing and start sweating profusely, mostly from the chest on up! I have been taking the med for about 6 weeks. In the beginning it was to help me stop my nasty smoking habit, but once I was on it for about 2 weeks I noticed I was very level, and that things that previously made me angry or annoyed just didn't bother me anymore. I had more patience with everything and felt a general sense of overall happiness. I always felt I was a very emotionally stable individual, but once I started on wellbutron I realized I really was not all that stable!! Unfortunately in the last few weeks I have begun the horrid sweating, my house became messy, I wanted to just stay home all day, and dreaded having to go anywhere, and felt as if I was "sick". I stopped taking the med for two days and feel better, but I am torn as to what to do seeing that i loved it in the beginning. Will these things level out and go away, or I am i doomed with the negative side affects if I continue with the meds?? Any helpful info or shared experiences would be greatly appreciated!

Posted by nancy on March 14, 2012 12:01 PM | Permalink | Reply

I experienced insane night sweats with Wellbutrin. I got to where I'd sleep on and under a towel and had some by the bed to switch out in the middle of the night. I felt awful with the sweating. Luckily it didn't happen during the day. It took a long time for the sweating to stop, but the annoyance of washing towels every day was a fair price to pay for the good that Wellbutrin did for me.

Posted by Lynn on March 21, 2012 6:08 PM | Permalink | Reply

My doctor perscribed wellbutrin for me as an add on to my regular SSRI 7 weeks ago. I was just starting to feel some good results with a more stable, mellow mood. Until last tuesday when, while having an important meeting with some colleagues, I had a grand mal seizure lasting from one to two minutes. I have never had a seizure before. After going to the hospital and having a complete work-up it has been decided that it was the wellbutrin that caused the seizure. I smashed my face up, bit my tounge so hard that I cannot speak! It was a terrifying experience and I have since learned that it is not all that uncommon especially with people taking the generic extended release.

I was happy with the results I was getting with wellbutrin until the seizure of corse. I would like to hear from others who have had seizures from this drug. How long were you on it before you had a seizure and did you ever have another seizure after the first one?

Posted by L. Mathews on March 29, 2012 6:08 PM | Permalink | Reply

I was on Lexapro and gained 30lbs it did keep me from having panic attacks. I switched six mo ago to pristiq half of min dose I lost seven lbs right away which was great. BUT I started having these waves of a physical feeling like I was so thirsty then right into a feeling of being totally weighted down. I would get these randomly and I would have to take a xanex to stop myself from going into panic mode. The dr said to up my dose to the min dosage. And within two weeks my husband was carrying me off a public bathroom floor to the ER. Nothing wrong they said. So my dr took me off the p and put me on 150 XL Well and the episodes started again but also with blurred vision and I also got bad chest pain. I stopped them cold two days ago, because of them I have paid $2000 for ER and $1500 for the cardiologist. Only to find out it was the meds. My advice to all is do not let an OBGYN or Primary give you any Antidepressant. Only a psychiatrist should be giving this stuff out. I am hoping through massive diet changes any everyday I exersize and meditate I can stay off it all. Has anyone had the feeling of being tied to bricks and like an instant surge and almost delirious feeling on W?

Posted by Chris on April 4, 2012 6:56 PM | Permalink | Reply

I have been on Bupropion for like a month...I can't sleep at all I feel like A zombie.I get like 3 hours of sleep in the morning sometimes none at all. Anyone else having problems not sleeping?

Posted by Deanna on April 9, 2012 10:06 AM | Permalink | Reply

I have had a terrific experience with Wellbutrin SR and in recent years, Wellbutrin XL.

The one warning I would offer is to not stop its use abruptly without medical supervision. I say this because on a few occasions, my daily routine became severely disrupted and it became difficult to remember taking my once per day dose of 450mg XL. On each of these occasions, I developed in about 5 to 7 days of non-use moderate dizziness, difficulty concentrating at work that bordered on confusion, and long, long periods of sleep (up to 30 hours).

Returning to my daily dose corrected all within a week but the side effects of abruptly stopping are so pronounced for me that they underscore the need to keep routines as faithfully as possible, including my morning dosing.

Posted by Tom on April 15, 2012 7:29 PM | Permalink | Reply

Started 100 mg 2x's a day of Wellbutrin (no generic) about 3 1/2 weeks ago. My side effects are migraines, sensitivity to light, extreme irritability, this "weird" feeling in my head, extreme ringing in my ears, and just terrible anxiety. Question is, will these side effects go away, should I up the dose, should I switch to XL??? I'm nervous that this my be hurting my brain. Taken for depression. HELP PLEASE!

Posted by Breeze on May 6, 2012 5:12 AM | Permalink | Reply

I have been taking this medication in the am for 150 mg for 4 days. My psychiatrist also increased my trileptal to 300mg a day. As far as far as side effects, the wellbutrin makes me tired during the day and makes me yawn all the time. I cant focus or concentrate like I used to (even though Ive been told it helps with ADHD). I am having a tough time making out sentences to people. I have become a bit more irritable at times for the littlest things. I get real bad blurry vision in the mornings, and upset stomach. It hasnt helped with depression at all so far. Are these side effects normal? How long till they go away? How long till I start seeing results? I am a student and I will be going back to school in two weeks. I dont want to keep dealing with these side effects cause it will disrupt me in school. I noticed blurry vision is not a common side effect, should I contact my doctor asap? Any advice would help! thanks!

Posted by Anonymous on May 20, 2012 8:43 AM | Permalink | Reply

My friend just started getting depressed due to some life situations. His dr. prescribed Wellbutrin and now he's committed suicide. This is a person who had everything and just needed help getting thru a tough time. Be very careful. He was not a person that would have ever committed suicide. Ever. Please, if you feel anxious or panic or depressed, please know that you are loved and there are tons of people out there to support you. Please don't end your life. It's really not the answer. The pain you leave behind is just not fair. Remember...you are LOVED!

Posted by Diane on May 25, 2012 8:59 AM | Permalink | Reply

Diane, I know what your friend was going through. I, too, felt such extreme suicidal thoughts that I attempted suicide a few years ago. I was hospitalized and diagnosed as bipolar. I hate to say it, but your friend was living a hellish life. There were times when I truly believed I was such a burden to everyone around me that I was "doing them a favor" by ending my life. My thoughts were "in time, they will forget me". Please remember that mental issues are a disease, just like diabetes or heart problems. Those too require meds to control the symptoms and no one blames that person of being "wrong" when they die of the disease. Your friend died of the disease, not selfishness or wanting to hurt anyone; and, you're right, the pain is just not fair for all parties.

Posted by Shelby on June 1, 2012 5:59 AM | Permalink | Reply

hello. I have been suffering from depression for the past12 years or so. I have been on several different meds. The dr. (a new one that listens!) put me on Wellbutrin about 5 weeks ago- 300mg. I was on Lexapro. Before I felt like I was in a deep dark hole, for the past couple of weeks I feel happier and I have crawled out of the hole and the sun is shining! I have energy, I am getting things done and am very motivated. However, my marriage is suffering. My husband has been dealing with depression for a couple of years and finally went in to see the dr. he put him on citalopram. He starting having ejaculation issues, and I was chipper on the wellbutrin- not a good match. The dr switched him to wellbutrin- 200mg about a week ago. This is my dilema- I am so needy, I want to spend every minute with my husband, I want to make love all the time, etc... Well, he does not feel that way. I have never been one to want to be intimate and would fall asleep first etc... He would wish that I wanted it more. I am overly sensitive as well. I am trying to figure out if the wellbutrin's pros out way the cons or if it is the other way around. I can not continue to feel this way, but I am scared to death that I will end up back in the hole. Any insights would be helpful. I wonder if lowering my dose would help?? thank you

Posted by ekrista on June 13, 2012 6:53 AM | Permalink | Reply

My doctor just increased my dosage of Wellbutrin xl to 300mg about 6 weeks ago and so far I have lost 14 pounds....is that normal? Should I be concerned?

Posted by Cai on June 24, 2012 10:00 PM | Permalink | Reply

I have been on Bupropion XI 300 mg once per day for three years, for mild depression and feelings of hopelessness. I love it. The first two weeks I had trouble sleeping, but that went away. My quality of life is much improved and I would like to take it for the rest of my life.

I would like to hear from anyone who may know about possible long term side effects. I am 61 years old and wonder if I can take this stuff for 20 or 30 more years without some awful, unforseen side effect that only occurs with long term use.

Posted by Andrea on June 27, 2012 5:19 AM | Permalink | Reply

Hi...I have been on 150mg W XL now since Feb 23 2012. It was rough I’m not going to lie. I didn’t think it was working at all....I doubled it on March 22 2012 (1 mth later). I must add I was hesitant to start anti depressants because I felt somehow like I failed myself...does that make sense? Like I thought maybe I was taking the easy way out etc. Was also scared of all the things I’ve heard that they are addictive etc. Anyway...I was so fed up with being sad I felt I had to do something. I am 34 and I "think" I have had ups and downs all my life but starting November 2011 I just couldn’t shake it and it got worse. Constant cloud of sadness over me is the only way I can describe it. I’ve been through, what I think, is a lot. 7 years with a semi emotionally abusive boyfriend. Then on to another man for 2 yrs that I think was no better. Ended up getting a illness called sarcoidosis...he dumped me because I was "milking" it. And said I should call my mom because he was not supposed to help me etc. Anyway...I got through all that and it was horribly depressing but I did it. It wasn’t until a year later the really bad depression hit. I have been fighting to get myself back. I feel I really have. Trying to research depression, reading books, CBT books...searching for a psychiatrist (covered by OHIP) which was so so so so so hard. Something is wrong with our health care system there. Anyways....When I doubled the meds I was so out of it. Foggy and depressed. Very scary. I was to the point I started to panic being alone and had to call my mom and sister to come over. I felt like Id lost it. I was encouraged to stay on the 300mg and that it would get better so I did. About a week later I thought I was feeling better symptom wise then BOMB I think I had a anxiety attack out of no where. Never had one before. And it hit me in the middle of a movie night with good friends and my new boyfriend. I ended up on the bathroom floor calling my mom again to come over. I lied to my new boyfriend and told him it was food poisoning. I was too embarrassed. The next day I went back to 150mg. I stayed there feeling very discouraged because I was still down. Then suddenly on April 7 I started to feel better. I was happy to feel this. Thought the meds were finally working. It lasted a few weeks but I started to have dips again. Great days then bad days. I am back to where I am at the verge of tears all the time. I am thinking negative thoughts about everything and I cant get myself out of it. Do anti depressants even work???? I’ve even been seeing a psychiatrist...which I may add I found with no help of my Dr. What is a psychiatrist supposed to do? I don’t get it. We just talk. I thought wed get down to some answers about why I’m feeling like this. I don’t know what to do at this point. I want so much to be happy and enjoy my life. What can I do? I feel this happy person inside but I can’t seem to get her to come out and stay out.

Posted by Denise on June 29, 2012 6:19 AM | Permalink | Reply

I have the same problem after just 2 weeks. Feels like I am getting early dementia. It is awful. I also feel like I don't know who I am any more.

Posted by Lj on July 2, 2012 8:03 PM | Permalink | Reply

Dear Ones, I have been on antidepressants since they invented Prozac. Been on and off most. First - I have found that you need a psychiatrist who (whether good bed side manners or not) KNOWS their drugs. - go to that Dr just for the drugs. For therapy find a psychologist or trained therapist for talking out issues. Your GP, internist or regular doc may care but the reality is they can not keep up with the volume of drugs being introduced out there and they deal with every field not just depression. Second - they have found that for a number of us the straight antidepressant DOES QUIT working, but upping the dose or changing to a new one will not solve the problem but adding a very small dose of Abilify, litium, Wb or Nerontin etc often does the trick. Although I think they are starting to address that issue with some of the new ones. Third- if one does not work another may do wonders! It just amazes me! Fourth - some you can taper doses and then stop. But NEVER try that with Paxil,Effexor or any of that generation of drug - withdrawal it is absolutely awful and does not stop however adding on and then switching to earlier generations like Prozac or Zoloft will ease it and once stable on those you can be tapered down. Fifth - let that frustration push you into pushing to find the right choice for you. There is not a magic pill that makes it all OK but there are pills that will help you smile and cope and not hurt inside. I want you to know there is hope !! Been there, done that!

Posted by Charlotte on July 4, 2012 5:28 AM | Permalink | Reply

As best

Posted by mike on July 11, 2012 4:06 PM | Permalink | Reply

First of all I am amazed that this conversation has been going on for 6 years.

I had a tummy tuck in 2009. My doctor, of course, put me on heavy pain meds which I became addicted to. When I realized I was addicted I sought help to get off the pain meds and started on suboxone, which is a miracle drug for people addicted to pain meds (no matter how much you take). It was the doctor that prescribed the Suboxone that diagnosed me with depression. I went to her crying my eyes out about how much I loved my children and was spending all my time with them and didn't want to do anything else. (Long story but I lost 70lbs working out plus I had a circle of about 4 friends that I would do stuff with regularly). I didn't want to work out, I didn't want to see my friends, and everything my husband and I did included the kids. I was seeing a therapist (maybe I should just write a book, lol) and he said I needed some adult time but still, when I my hubby brought home 4 tickets to see the Tigers, I took the kids. Anyway, back to the doctor that diagnosed me. She said I had all the classic signs and my other doctor had been overlooking them. She prescribed Wellbutrin 150 XL. I have only been taking them for about 10 days. I don't have much feelings at all. We are currently on vacation and yesterday we were at an amusement park and I didn't feel excitement about anything. I am however having crying spells everyday but remember, I was crying the day the doctor diagnosed me so I can't blame that on the medicine. After reading all the posts above, and even going back and reading the missing posts that someone posted for Cheryl, I am looking forward to what this medicine can do. I am not convinced I am depressed but I have been having these feelings for a couple years. I think they could be caused by circumstances but I'll be open-minded for now. Thanks to everyone who has posted. Keep sharing, it helped me and I'm sure it helps other people too!

Posted by Inandout on July 16, 2012 6:55 AM | Permalink | Reply

Hi everyone,

I started on Bupropion 5 weeks ago to help me with depression and severe fatigue - more like physical exhaustion. For the first 2 weeks, I took 150 mg and my doc upped the dose to 300 mg that I've been taking for the last 3 weeks.

At first, I had NO side effects except for a couple of nights where I woke up at 2am with heartburn and was able to get back to sleep after sipping a glass of water. After the first 2 weeks, my doc asked me if I was feeling 'astoundingly' better. I said that I wasn't as fatigued but certainly not astoundingly better.So the doc upped my dosage. Over the last 3 weeks, I've had SEVERE heartburn at night (not every night but frequent enough), and nothing I took (like extra strength Zantac) was/is helping. The other thing I just started noticing is my anxiety level is through the roof...I'm wondering if I should drop back down to the 150 mg or just wait it out some more...Thoughts anyone?

Posted by Lisa on August 8, 2012 7:13 PM | Permalink | Reply

I was on wb for 1 month,,i have ms with extreme fatigue so my dr said this would give me energy,wweellll, i got everything but energy! I had to stop cold turkey! Couldn't deal with anxiety ,painic feeling, can't breath, paranoid, suicidle thoughts , which is absolutely crazy that this pill can do that with your thoughts!! It's been hell and just want this night mare to stop!! It will be one month this week that I have been off it and afraid now that since I've entered the depths of hell,,,,that I can get out?!?! Any thoughts???

Posted by Roma on August 18, 2012 3:01 PM | Permalink | Reply

I hve been on WXL for about a year now, I was on Zolft for 3 month before that which I hated as I felt like a zombie! Love WXL, but now my blood pressure has gone fom 110/70 to 155/95, doctor gave me a script or 150mg (I'm on 300mg at present) told me to see If that lower dose lowers my BP. She told me to take 150mg for 2 weeks and also try 2 weeks not takin anything, keepin track of BP. I'm hoping it gets lower on the lower dose as I suffer frm SAD and winter is coming! Apparently it's fine to just stop taking WXL.

Posted by Sue on August 19, 2012 8:07 AM | Permalink | Reply

I took Wellbutrin xl 300 for 8 months, I had absolutely no side effects on the drug, and I stoped cold turkey a few months ago! I was not depressed, I just took it to lose a few extra lbs and to help quit my smoking addiction.....It did not work! I actually thought maybe the puls were sugar tablets, just bizarre!! A friend took the 150xl and lost nearly 60 lbs! So, who is to say there is a right or wrong drug! You gotta take it to see results, or no results... In my case. I was never depressed and I pray that I never am as I deal with it on a daily basis with my husband, my child, and half of my family... It's a shame that anyone has to live with this disease! I bow to you all for having to deal with it!!

Posted by Just a woman on September 12, 2012 10:55 PM | Permalink | Reply

I have been on welbutrin for about twelve years due to severe depression brought on by an autoimmune thyroid desease [hashimotos syndrome].
I was on 150ml twice a day which eventually seemed to help...although the side effects, nervousness, dissiness, dry mouth, irritability, sleeplessness, anxiety, even delusional thinking were quite strange to me. However...either I got used to them or they subsided somewhat and I kept taking my WB. With steady bloodtests testing synthroid medicine levels, my thyroid eventually stabilzed...although I initially lost around 30 lbs in the process.
Because I was then feeling better, my Doctor lowered my WB dose to 150ml.XL once a day...which I continued on for several years. I stopped taking WB for around two years...because I felt better at that time...but still had mild dysthymia most of the time. I decided to go back on a daily dose of 150ml and kept it up till last spring, when I had another severe depressive episode. I immediately went back to my endocronologist and discovered that I was hyperthyroid and my sythroid dose had to be lowered. The higher dose of sythnthroid was also causing rather severe Atrial-Fibralation...so when Dr. lowered the dose that also subsided.
The real issue occured when I was put on a higher dose of WB [150ml twice a day] that I took in generic form...to save money. It seemed I immediately felt different and reactions were my feeling very manic, anxiety ridden, agitation, dizziness along with bouts of paranoia and delusional thoughts.When I told the Pharmicist of this, she told me that basically it was the same ingredients...so she didn't think it would affect me as such. It is now Oct. and I have just now lowered my dose, with Doctors approval, to 150ml. a day and am hoping to see a difference...we'll see. My question is; knowing that many generics are manufactured in 'other countries' to save cost...could they still be made as correct as the 'real' meds? Who supercedes this to make certain? As I am still experiencing some sort of reaction now and then...shouild I just go back on the regular Welbutrin and stick to that?
Also...as a long time WB user, how do you ever get off this medicine without experiencing worsened depression...etc..? As a 'first generation WB user', am I really just a test subject for all of this?
I would also advise those who are just getting diagnosed with depression to take a simple blood test to determine that your thyroid is functioning correctly. If it is not...most depression meds will NOT work until the thyroid level is back or close to normal again...and that can take several months.

Posted by Dan on September 28, 2012 7:34 AM | Permalink | Reply

I'm on wellbutrin & am not sure if it's right for me. I've noted more hostility but I've a new found confidence so who knows. As for everyone arquing why not be positive and help one another. I have bipolar & with out my medicine I cannot function like the majority of most people. I'm a perfect example of why medication can actually help. If anyone has a positive response for me I'd love to hear it. And for those who are arguing, you are entitled to say what you want, but on this forum it's not productive and it's extremely insenstive. These can be very difficult situations and if you haven't been there pleae don't get on your high horse, all any of us need is support. We all are fighting are own battles, why add to others? Thank you and I hope more positive responses take up this page.

Posted by natalie on October 13, 2012 9:21 PM | Permalink | Reply

Taking wb since 2006. 300 mg a day. Changed my life! Was a little shaky at first taking 350, but after reducing to 300, no problems. Best decision I ever made!

Posted by JG on October 16, 2012 7:18 PM | Permalink | Reply

I took this when I was in the hospital for 3 days they thought I was depressed but misdiagnosed me. I came home to a house that didn't feel like mine, ate different foods I used to love hot tea haven't been able to look at it since, quit smoking cigarettes for 5 years and had to re-learn to love my husband and animals they all felt like strangers to me. I only took this for three days.

Posted by kathy miller on November 20, 2012 8:15 AM | Permalink | Reply

Wow I read all this and am relieved. My husband and I started taking Bupropion 150 mg twice a day. I had already been taking Klonopin for panic attacks for two weeks. We seemed ok for the first two weeks. Over the last 3 weeks I have experienced anxiety so severe I am on the edge of a panic attack at all times but never actually go into one, I am paranoid and don't know why, I cry all the time for no reason and in school too which is embarrassing,over the last week my chest hurts, I feel like I am not getting enough air or too much air don't even know which, I am scared to go to sleep at night in my bed because I think my brain is associating my bed with anxiety and breathing problems and now go out and sleep upright on the couch with the TV to relieve the paranoid feelings I have. I have had the feeling of something in my throat and the yawning too. I read this and I started reading all these to my husband and it was like I have decribed these feelings to my husband over the last two weeks. This past Sunday I had a meltdown..crying, gasping for breath, feeling like I couldn't swallow and something was in my throat. I have stopped taking it cold turkey on my second day and feeling a little better and hope all this goes away.

Posted by Priscilla on November 23, 2012 9:21 AM | Permalink | Reply

Oh we were taking the Bupropion for quitting smoking.

Posted by Priscilla on November 23, 2012 9:22 AM | Permalink | Reply

I have been on Wellbutrin for 2 weeks and now know what anxiety is all about. If this keeps up I am going to lose my job. I have near panic attacks even when the phone rings! It is not waning and I dread the 6 hours after my second daily dose. So not only do I have depression, but now anxiety. Crying often and feeling like throwing up the rest.

Posted by Jennifer on February 21, 2013 4:14 PM | Permalink | Reply

I read all these bad reactions and side effects, and I feel like the luckiest person in the world. I just started Bupropion SR (the Wellbutrin generic) at 150mg two times a day (300 total) and I'm almost through week 2. I'm actually happy to report that I'm tolerating it really well. Which is surprising because I've tried EVERYTHING from SNRIs, SSRIs, MAOis, Tricylics, Antipsychotics, mood stabilizers, etc and typically 70% of the time have to come off them within 2-3 weeks due to being unable to tolerate how I react to the drugs.
On the Wellbutrin though I experienced dry mouth the first 2 days that went away right quick, and currently am only dealing with loss of appetite, mild insomnia (which is improving) and slight mania (In that I feel more energetic, really focused, I talk a LOT to the point of sometimes annoying others, and in turn have issues sleeping). There were some issues early on with irritability, but that went away somewhat quickly as well.
I'm REALLY hoping this is something that will help me (with or without combination) because my body is handling it really well.
I'm sorry so many of you have issues with the drug. I've had my share of bad reactions too (Some were just absolutely horrendous), but that's the dice roll with these kinds of meds. Some people don't tolerate them, others do. You just have to find what fits you. Best of luck to everyone on finding what works for them.

Posted by Karen on March 4, 2013 3:22 AM | Permalink | Reply

I have had terriable side effects taking Bupropion XL 150mg. dizziness,jitters lost concentration, hearing music and other sounds in my head they play over and over,driving me crazy also headaches How long does it stay in your system. I stopped taking it today. How long before the side effects go away

Posted by Anonymous on April 13, 2013 2:01 PM | Permalink | Reply

I have had terriable side effects taking Bupropion XL 150mg. dizziness,jitters lost concentration, hearing music and other sounds in my head they play over and over,driving me crazy also headaches How long does it stay in your system. I stopped taking it today. How long before the side effects go away

Posted by Alice Dartt on April 13, 2013 2:02 PM | Permalink | Reply

I have been on WB for maybe 2 weeks. Switched anxiety meds hoping this one wouldn't make me pee all the time! I now get nauseous a lot! Am starting to come off of the drug because I can't stand feeling like I wanna puke all the time..

Posted by Anonymous on April 14, 2013 4:24 PM | Permalink | Reply

I am on Day 4 of Wellbrutin after being in the darkest most anxious place these last few months. One of the things I was concerned with when I talked to my doctor about getting put on an anti depressant was the weight gain. I am overweight as it is and my low self esteem and warped sense of body image is one of the factors that keeps me from getting out of bed everyday. She reccomended Wellbutrin as it helps with anxiety, depression, and appetite suppressant for most of the people that take it. The first three days were rough. I was anxious and tearful. I had a lot of energy and little appetite and was overall sad. Now I am on Day 4 and I feel energized and hopeful. I just cleaned my entire house on a Friday night because I had the energy and want to do so. That's just me when I'm depressed! So I'm going to give this drug a shot and see where itt takes me. Even if its only a quarter of the time I can feel "normal", I will take it!

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