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Paxil Side Effects


Paxil (paroxetine hydrochloride) is a selective serotonin reuptake inhibitor (SSRI) antidepressant marketed by GlaxoSmithKline.

Paxil is approved to treat depression, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), generalized anxiety disorder, social anxiety disorder, panic disorder, and premenstrual dysphoric disorder (PMDD).

It has been used off-label to treat bipolar disorder, chronic headache, hot flashes, compulsive gambling, and diabetic neuropathy.

Paxil CR is the controlled release verson of Paxil, meaning it is released slowly into the body for continuous effect.

According to the official Paxil website, common side effects may include nausea, infection, diarrhea, dry mouth, injury, constipation, sleepiness, increased appetite, sexual side effects, tremor, nervousness, yawning, sweating, weakness, abnormal vision, or insomnia.

More serious side effects may include suicidal thoughts, worsening depression, or severe changes in mood or behavior.

This space is provided for you to share your side effects (or lack thereof) and experiences with Paxil and Paxil CR by posting a comment below.

Filed under Drug Side Effects, GlaxoSmithKline, Paxil

Comments (4) | Leave a comment

I took Paxil for six months for depression.

It made orgasm impossible and caused spontaneous defecation. I wasn't depressed anymore, but I kept crapping my pants.

I switched to another SSRI (Luvox) and had a lot more luck with it.

Posted by Moose on April 17, 2007 11:05 AM | Permalink | Reply

Yikes, Moose--sorry to hear about that! Good you've found something that works better for you. Other than difficulty reaching orgasm and night sweats, I tolerate Paxil pretty well. However, for those just starting it, beware that the adjustment period can be quite awful with lots of physical and mental discomfort. For me, I just kept telling myself to hang in there, and after 3 weeks or so, the side effects started to subside. I do think it's important to combine the meds with other positive changes for best results (e.g., exercise, personal growth, pursuing healthy relationships and getting rid of unhealthy ones, etc.). Good luck, everyone!

Posted by Todd on May 30, 2007 11:15 PM | Permalink | Reply

The suicidal thoughts is the one thing that would make me rethink taking Paxil. There are so many people under stress from the economy that the thought of desperation mixed with a drug that has this side effect may be a really bad combination.

Posted by Ajlouny on July 13, 2009 6:10 PM | Permalink | Reply

started paxil over a month ago. It did take three weeks to get in my system. I think it is great i am on a low dose. I do not get annoyed as often and have a lot more patience with everyone. I also find it helps with my eating I have been able to maintain a healthier weight.

Posted by sarah on December 12, 2009 4:07 AM | Permalink | Reply

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