Health Diaries > Prescription Drug Watch
Paxil Side Effects
Paxil (paroxetine hydrochloride) is a selective serotonin reuptake inhibitor (SSRI) antidepressant marketed by GlaxoSmithKline.
Paxil is approved to treat depression, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), generalized anxiety disorder, social anxiety disorder, panic disorder, and premenstrual dysphoric disorder (PMDD).
It has been used off-label to treat bipolar disorder, chronic headache, hot flashes, compulsive gambling, and diabetic neuropathy.
Paxil CR is the controlled release verson of Paxil, meaning it is released slowly into the body for continuous effect.
According to the official Paxil website, common side effects may include nausea, infection, diarrhea, dry mouth, injury, constipation, sleepiness, increased appetite, sexual side effects, tremor, nervousness, yawning, sweating, weakness, abnormal vision, or insomnia.
More serious side effects may include suicidal thoughts, worsening depression, or severe changes in mood or behavior.
This space is provided for you to share your side effects (or lack thereof) and experiences with Paxil and Paxil CR by posting a comment below.
Filed under Drug Side Effects, GlaxoSmithKline, Paxil
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I took Paxil for six months for depression.
It made orgasm impossible and caused spontaneous defecation. I wasn't depressed anymore, but I kept crapping my pants.
I switched to another SSRI (Luvox) and had a lot more luck with it.
Yikes, Moose--sorry to hear about that! Good you've found something that works better for you. Other than difficulty reaching orgasm and night sweats, I tolerate Paxil pretty well. However, for those just starting it, beware that the adjustment period can be quite awful with lots of physical and mental discomfort. For me, I just kept telling myself to hang in there, and after 3 weeks or so, the side effects started to subside. I do think it's important to combine the meds with other positive changes for best results (e.g., exercise, personal growth, pursuing healthy relationships and getting rid of unhealthy ones, etc.). Good luck, everyone!
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The suicidal thoughts is the one thing that would make me rethink taking Paxil. There are so many people under stress from the economy that the thought of desperation mixed with a drug that has this side effect may be a really bad combination.

As with other anti-depressant meds, I experienced less interest in sex. It was also more difficult to have an orgasm.
On a positive note, in dealing with people that were difficult or unreasonable, I found it no longer bothered me.
"Better living through chemicals!"